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Discover 6,654 Texas Medical Center hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

InterContinental Houston, an IHG Hotel
International cuisine
InterContinental Houston, an IHG Hotel
4.0 star property
9.4 out of 10, Exceptional, (1002)
"The staff was excellent! "
The price is $161
$203 total
includes taxes & fees
May 11 - May 12
InterContinental Houston, an IHG Hotel
Best Western Plus Downtown Inn & Suites
Sports facility
Best Western Plus Downtown Inn & Suites
3.0 star property
9.4 out of 10, Exceptional, (1006)
"It was amazing I loved it "
The price is $126
$148 total
includes taxes & fees
May 14 - May 15
Best Western Plus Downtown Inn & Suites
Home2 Suites by Hilton Houston Medical Center, TX
Terrace/patio
Home2 Suites by Hilton Houston Medical Center, TX
3.0 star property
9.4 out of 10, Exceptional, (268)
"I loved every aspect"
The price is $135
$158 total
includes taxes & fees
May 23 - May 24
Home2 Suites by Hilton Houston Medical Center, TX
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Locale Medical Center - Houston
Outdoor pool
Locale Medical Center - Houston
4.0 star property
9.4 out of 10, Exceptional, (194)
"Great place to stay. Communication to get into property upon arrival was difficult. Everything else was wonderful. "
Locale Medical Center - Houston
Hyatt Place Houston Medical Center
Lobby
Hyatt Place Houston Medical Center
3.0 star property
9.2 out of 10, Wonderful, (619)
"A great place."
The price is $125
$146 total
includes taxes & fees
May 12 - May 13
Hyatt Place Houston Medical Center
JW Marriott Houston Downtown
Exterior
JW Marriott Houston Downtown
5.0 star property
9.2 out of 10, Wonderful, (1002)
"The 6 day stay was amazing. It started immediately, as when I checked in I was upgraded to a suite. The staff in all areas functioned at the pinnacle of professionalism. From the spa to thevredtsurantvto the front desk and door staff, I couldn't have hoped for a better experience."
The price is $254
$311 total
includes taxes & fees
May 19 - May 20
JW Marriott Houston Downtown
Four Seasons Hotel Houston
Outdoor pool, cabanas (surcharge), pool umbrellas
Four Seasons Hotel Houston
5.0 star property
9.2 out of 10, Wonderful, (1020)
"Really lovely, fancy hotel. The staff were nice and agreeable but lacked follow through. We were missing a couple of items in our rooms, requested them from staff, and then they were never delivered. I was told they would accommodate our request for quiet rooms, and we were placed by an ice machine, a door where staff were coming and going, and above the pool where they play music evenings and weekend. Also a lack of fast casual dining. I was there with teens, but the dining in the hotel was...
The price is $480
$565 total
includes taxes & fees
May 6 - May 7
Four Seasons Hotel Houston
The Westin Houston Downtown
Premium bedding, pillowtop beds, in-room safe, desk
The Westin Houston Downtown
4.0 star property
9.2 out of 10, Wonderful, (1001)
"Loved it. I remember hanging out and staying there when it was Inn at the Ballpark. Loved it. Bar area closes a little early for a weekend. 12 would have been better, so many people and they shut ya down. Worked for our family purpose for the weekend. The remodel is awesome. "
The price is $178
$208 total
includes taxes & fees
May 19 - May 20
The Westin Houston Downtown
Homewood Suites Houston Downtown
Lobby lounge
Homewood Suites Houston Downtown
3.0 star property
9.2 out of 10, Wonderful, (745)
"Everything was wonderful. The area was a little concerning as far as safety, at night."
The price is $152
$180 total
includes taxes & fees
May 10 - May 11
Homewood Suites Houston Downtown
La Colombe d'Or Hotel
Front of property
La Colombe d'Or Hotel
5.0 star property
9.0 out of 10, Wonderful, (63)
"Exceeded our expectations - we were upgraded to stay in a mansion suite vs a room in the tower, which felt too good to be true but we said okay - the suite was amazing, felt luxurious and we loved it BUT directly outside the Van Gogh suite there must be a staff hallway or closet immediately outside the door and you can hear it open and close fairly loudly because of course it’s an old mansion - my husband and I didn’t mind it, totally worth the noise but other people who are more sensitive to...
The price is $428
$500 total
includes taxes & fees
May 25 - May 26
La Colombe d'Or Hotel
The Westin Oaks Houston at the Galleria
Meeting facility
The Westin Oaks Houston at the Galleria
4.0 star property
8.8 out of 10, Excellent, (1005)
"Nice property. Would stay again"
The price is $215
$255 total
includes taxes & fees
May 10 - May 11
The Westin Oaks Houston at the Galleria
Staybridge Suites Houston - Medical Center, an IHG Hotel
Exterior
Staybridge Suites Houston - Medical Center, an IHG Hotel
3.0 star property
8.8 out of 10, Excellent, (588)
"The environment was wonderful. Amazing staff, there to help and answer questions. Breakfast was fantastic with kind staff as well. We will be back!!"
The price is $125
$146 total
includes taxes & fees
May 12 - May 13
Staybridge Suites Houston - Medical Center, an IHG Hotel
Courtyard by Marriott Houston Medical Center/NRG Park
Outdoor pool, pool umbrellas
Courtyard by Marriott Houston Medical Center/NRG Park
3.0 star property
8.6 out of 10, Excellent, (1005)
"The stay was very comfortable, and attendants were courteous. "
The price is $101
$119 total
includes taxes & fees
May 26 - May 27
Courtyard by Marriott Houston Medical Center/NRG Park
Residence Inn by Marriott Houston Downtown/Convention Center
Exterior
Residence Inn by Marriott Houston Downtown/Convention Center
3.0 star property
8.6 out of 10, Excellent, (649)
"What a brilliant hotel!!! The staff were outstanding! My room was huge and extremely well-equipped (“full kitchen” literally means a full kitchen…!). The included breakfast was plentiful and the breakfast room was big enough to accommodate many people. I loved everything about this hotel! Being downtown, homelessness in the area is evident, but the hotel is secure. The area is walkable. I wouldn’t stay anywhere else in Houston. As I said, the staff were amazing and are a true asset to the hotel....
The price is $118
$140 total
includes taxes & fees
May 27 - May 28
Residence Inn by Marriott Houston Downtown/Convention Center
Comfort Suites near Texas Medical Center - NRG Stadium
Lobby
Comfort Suites near Texas Medical Center - NRG Stadium
2.5 star property
8.6 out of 10, Excellent, (494)
"Very clean quiet. Easy to get to medical facility. If we need to go back to hospital this is the hotel I will stay at "
The price is $92
$107 total
includes taxes & fees
May 27 - May 28
Comfort Suites near Texas Medical Center - NRG Stadium
Springhill Suites by Marriott Houston Dwntn/Convention Cntr
Exterior
Springhill Suites by Marriott Houston Dwntn/Convention Cntr
2.5 star property
8.4 out of 10, Very Good, (1001)
"Great location "
The price is $116
$137 total
includes taxes & fees
May 12 - May 13
Springhill Suites by Marriott Houston Dwntn/Convention Cntr
Sonder The Hogg Palace
Full-size fridge, microwave, oven, stovetop
Sonder The Hogg Palace
3.5 star property
8.4 out of 10, Very Good, (596)
"All good"
The price is $174
$204 total
includes taxes & fees
May 31 - Jun 1
Sonder The Hogg Palace
Homewood Suites by Hilton Houston Near the Galleria
37-inch LCD TV with digital channels, TV, pay movies
Homewood Suites by Hilton Houston Near the Galleria
3.0 star property
8.4 out of 10, Very Good, (1003)
"Nice property in a good location. Staff was friendly and accommodating. "
The price is $110
$129 total
includes taxes & fees
Jun 2 - Jun 3
Homewood Suites by Hilton Houston Near the Galleria
Hampton Inn & Suites Houston Medical Center NRG Park
Property entrance
Hampton Inn & Suites Houston Medical Center NRG Park
2.5 star property
8.4 out of 10, Very Good, (1001)
"Loved the upgraded look. Loved the option to park in a secured gated parking area. Would have loved to have had time for the breakfast but was limited on time - it looked wonderful. Wish the trash in the bathroom would have been taken out (wasn’t much but still should have been removed). The fridge needed to be leveled and possibly replaced - it was stained and had too much moisture inside. Adjusting the temp didn’t really help. For the Hampton, the in room coffee “pot” was subpar. The least...
The price is $88
$104 total
includes taxes & fees
May 10 - May 11
Hampton Inn & Suites Houston Medical Center NRG Park
The Whitehall Houston
City view from property
The Whitehall Houston
4.0 star property
8.2 out of 10, Very Good, (1006)
"Great location. We was close to everything and the highway. The only issue we had was the power going off and there was no back up generator, we had to wait until the problem was fixed.."
The price is $143
$167 total
includes taxes & fees
May 10 - May 11
The Whitehall Houston
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Other neighborhoods around Texas Medical Center

Hotels in top Houston neighborhoods Learn more about Texas Medical Center
Discovery Green which includes a city, central business district and a high rise building

Downtown Houston

3 out of top 10 points of interest in this area
4.5/5(2,300 area reviews)

Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.

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Texas Medical Center Travel Info

Number of reviews
14,774
Location
Houston, United States of America
Similar neighborhoods
Southeast Houston, Houston Central Business District and The Galleria
Accommodation
6,654 hotels
Known landmarks
Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston
Hotels with family-friendly amenities
Motel 6 Houston, TX - Medical Center/NRG Stadium, Americas Best Value Inn NRG Park Medical Center and Scottish Inns & Suites at NRG Park
Lowest price
$88
Highest price
$480

Frequently asked questions

What is Texas Medical Center like?

Texas Medical Center is a neighborhood that travelers like for its museums, shopping, and zoo. Looking for sights you might find in a travel guide about Texas Medical Center? Consider a visit to Houston Zoo while you're in the neighborhood.

What's a favorite hotel to stay in Texas Medical Center?

Based on Expedia customer reviews, Hilton Garden Inn Houston Medical Center, TX is the highest ranked property in Texas Medical Center. This hotel offers a restaurant and an outdoor pool. Other favorite options in the area include Home2 Suites by Hilton Houston Medical Center, TX and Blossom Hotel Houston.

How many hotels will I find in the Texas Medical Center area?

Expedia has 260 hotels and other accommodations in Texas Medical Center to choose from, making this an ideal home base for exploring the greater Houston area.

If I need to cancel my hotel reservation in Texas Medical Center, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might still have the option to cancel and be given a refund within 24 hours of your booking. Put your dates in and click on "Search", then use the "fully refundable" filter to review the top deals on offer in Texas Medical Center.

Where can I learn more about changing or cancelling my trip to Texas Medical Center?

For more information about picking new dates or cancelling your trip to Texas Medical Center, go to https://www.expedia.com/service/.

What can I see and do in this Houston neighborhood?

Popular attractions in Texas Medical Center include Houston Zoo. A visit to Hermann Park is also worth the trip while you're discovering the neighborhood. A few places to visit in the area around Texas Medical Center include NRG Stadium, Reckling Park, and Tudor Fieldhouse. When you're sightseeing in Houston, Rice Stadium and Miller Outdoor Theater are also worth a stop.

How can I get around Texas Medical Center and the greater Houston area?

For a quick way to explore the city, catch a ride on metro transit at TMC Transit Center, Dryden/TMC Station, or Smith Lands Station.

Recent reviews of Texas Medical Center hotels

Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

5/5 Excellent
"The hotel staff was very friendly , the place was very well kept and very clean. I would recommend this stay anyone. Also loved the the cafe they had food was so good. "
A verified traveler stayed at Club Quarters Hotel Downtown, Houston
Posted 21 hours ago
Club Quarters Hotel Downtown, Houston