Find hotels in Santee, SC from $56

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Compare 228 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Lobby
Quality Inn & Suites
2.5 star property
6.6 out of 10, (225)
"Very friendly and courteous"
The price is $59
$70 total
includes taxes & fees
Jun 5 - Jun 6
Quality Inn & Suites
Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi
Baymont by Wyndham Santee
2.5 star property
7.8 out of 10, Good, (1322)
"Excellent stop off of l95 . "
The price is $75
$83 total
includes taxes & fees
Jun 4 - Jun 5
Baymont by Wyndham Santee
Property amenity
Fairfield Inn & Suites by Marriott Santee
2.5 star property
9.8 out of 10, Exceptional, (998)
"The hotel was very clean, the employees were friendly and helpful and the rooms were comfortable with everything you need. They even provided an antibacterial wipe next to the telephone to make you feel a little better about using it!"
The price is $142
$158 total
includes taxes & fees
Jun 3 - Jun 4
Fairfield Inn & Suites by Marriott Santee
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Premium bedding, desk, laptop workspace, iron/ironing board
Days Inn by Wyndham St George
2.5 star property
7.2 out of 10, Good, (1008)
"Very nice for one night "
The price is $56
$62 total
includes taxes & fees
May 28 - May 29
Days Inn by Wyndham St George
Exterior
Holiday Inn Santee, an IHG Hotel
3.0 star property
8.2 out of 10, Very Good, (743)
"Needs reconditioning"
The price is $159
$176 total
includes taxes & fees
Jun 3 - Jun 4
Holiday Inn Santee, an IHG Hotel
Exterior
Best Western Plus Santee Inn
2.5 star property
8.6 out of 10, Excellent, (1001)
"Great stay again"
The price is $122
$136 total
includes taxes & fees
Jun 4 - Jun 5
Best Western Plus Santee Inn
Lobby
Comfort Inn & Suites Santee
2.5 star property
8.0 out of 10, Very Good, (841)
"Solid no-frills property. Rooms are clean and decent sized. Staff was very friendly"
The price is $124
$138 total
includes taxes & fees
Jun 4 - Jun 5
Comfort Inn & Suites Santee
Exterior
Hampton Inn Santee-I-95
2.5 star property
9.6 out of 10, Exceptional, (1004)
"The front desk young lady was friendly and polite even at midnight. The room was clean. The kitchen staff were nice and came out to speak to the guest. This was a refreshing experience and we have saved the location for our next trip."
The price is $153
$170 total
includes taxes & fees
Jun 23 - Jun 24
Hampton Inn Santee-I-95
Exterior
Travelodge by Wyndham Santee
2.0 star property
7.0 out of 10, Good, (493)
"Clean and quiet. Affordable. I would stay again "
The price is $60
$67 total
includes taxes & fees
May 28 - May 29
Travelodge by Wyndham Santee
Lobby lounge
Red Roof Inn St George, SC
2.5 star property
7.8 out of 10, Good, (494)
"My initial room smelled of smoke and had moldy grout in the bathroom. I requested a room change and the other room on the 2bd floor was cleaner."
The price is $63
$70 total
includes taxes & fees
May 28 - May 29
Red Roof Inn St George, SC
Front of property
Peach Tree Inn
2.5 star property
6.8 out of 10, (1000)
"Did like it "
The price is $70
$76 total
includes taxes & fees
May 28 - May 29
Peach Tree Inn
Lobby
Rodeway Inn Santee I-95
2.0 star property
6.2 out of 10, (498)
"Room #1 - was a little disappointing as it was not totally smoke free. Cigarette smoke could be smelled as soon as you entered. Once the bathroom exhaust fan & A/C fan came on the smoke was stronger. There were also items that were broken or hanging off the wall. Then came a group of people associating near the room, smoking. I then requested to be moved. Room # 2 was excellent no odors, very clean and comfortable. I was very pleased. Staff was professional and helpful. "
The price is $90
$100 total
includes taxes & fees
May 30 - May 31
Rodeway Inn Santee I-95
Exterior
Red Roof Inn Santee
2.0 star property
6.4 out of 10, (558)
"Overall it was a great nights stay. Clean and quiet. Will stay there again when I pass through Santee. The other hotels have gone crazy with there rates."
The price is $70
$78 total
includes taxes & fees
May 28 - May 29
Red Roof Inn Santee
Exterior
Econo Lodge
2.0 star property
6.4 out of 10, (302)
"It was great"
Econo Lodge
Lobby
Super 8 by Wyndham Santee
2.0 star property
6.6 out of 10, (391)
"Size of the room"
The price is $75
$83 total
includes taxes & fees
May 28 - May 29
Super 8 by Wyndham Santee
Lobby
Econo Lodge St George
2.0 star property
6.2 out of 10, (203)
"Clean room, excellent staff, accomodating, great bed, stayed many times over the years, highly recommend"
The price is $64
$69 total
includes taxes & fees
Jun 9 - Jun 10
Econo Lodge St George
Outdoor pool
Wyndham Vacation Resorts Lake Marion
4.0 star property
9.4 out of 10, Exceptional, (15)
"I enjoy my stay, customer service was exceptional. Will book again. "
Wyndham Vacation Resorts Lake Marion
Room, 2 Double Beds | Desk, free WiFi, bed sheets
Knights Inn Saint George
1.5 star property
6.0 out of 10, (132)
"Nice clean room"
The price is $60
$67 total
includes taxes & fees
May 28 - May 29
Knights Inn Saint George
Fridge, oven, stovetop, coffee/tea maker
Cozy home. 15 minutes from the lake and 30 minutes from the beach!
10.0 out of 10, Exceptional, (2)
"Awesome host and place"
The price is $105
$227 total
includes taxes & fees
May 28 - May 29
Cozy home. 15 minutes from the lake and 30 minutes from the beach!
Outdoor pool
Executive 2 BR/2 BA Lakefront Corner Suite Condo
9.4 out of 10, Exceptional, (21)
"My stay was amazing. It made me felt as if I was at home. The unit was very clean and well organized. I will definitely be booking this condo again in the near future."
Executive 2 BR/2 BA Lakefront Corner Suite Condo
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See all available properties in Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More cheap stays in Santee

Stay near popular Santee attractions

Santee Travel Info

Number of reviews
4,886
Accommodation
228 hotels
Highest price
$159
Lowest price
$56
Reasons to visit
Santee State Park, Santee Cooper Country Club and Santee National Golf Club
Hotels with golf
8
Hotels with family-friendly amenities
3

Frequently asked questions

Where is the best place for a stay in Santee?

Fairfield Inn & Suites by Marriott Santee is a favorite property for Expedia customers. This hotel offers free breakfast and an outdoor pool. Other top choices based on traveler reviews include Hampton Inn Santee-I-95 and Tru By Hilton Santee. See all available top hotels, or vacation rentals in Santee.

What are some of the best vacation rentals in Santee?

Mary's Place​ -A waterfront retreat on Beautiful Lake Marion : Visitors like this Santee vacation home rental. It is located on a lake and has a fireplace, a patio, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. It offers a garden, a selection of games, and a spa tub so you can immerse yourself in your vacation. See all vacation rentals in Santee.

If I need to cancel my hotel reservation in Santee, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santee.

Where can I learn more about changing or cancelling my trip to Santee?

For more information about updating your trip to Santee or cancelling it, click here.

What's the best budget-friendly hotel in Santee?

Based on reviews, Baymont by Wyndham Santee is a popular hotel for our travelers who want a more economical choice, and features free breakfast and free WiFi. View all budget hotels in Santee.

What's the best hotel for a family vacation in Santee?

Comfort Inn & Suites Santee is a hotel with free parking and free buffet breakfast, and it's a top choice on Expedia for families. Fairfield Inn & Suites by Marriott Santee is another choice for your family trip. Find more child-friendly accommodations in Santee.

What is the top LGBTQ-friendly accommodation in Santee?

Fairfield Inn & Suites by Marriott Santee is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Hampton Inn Santee-I-95 and Holiday Inn Santee, an IHG Hotel are other good options for your stay. See all available hotels listed as LGBTQ-friendly in Santee.

What's the best pet-friendly accommodation in Santee?

Baymont by Wyndham Santee is a top hotel for people traveling with their pets, and offers concierge services and free WiFi for its human guests. Other good choices for you and your pet's trip include Quality Inn & Suites and Tru By Hilton Santee. See more pet-friendly hotel accommodations in Santee.

Where is the best place to stay near Santee State Park?

Baymont by Wyndham Santee is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. It's located 3 mi (4.8 km) from Santee State Park. Other good choices within 5 miles include Best Western Plus Santee Inn and Holiday Inn Santee, an IHG Hotel.

What about the best place to stay close to Santee Outlets?

One of the top choices for your stay is Baymont by Wyndham Santee, located a short 0.4 mi (0.6 km) from Santee Outlets, and this hotel offers free breakfast and free parking. Best Western Plus Santee Inn and Fairfield Inn & Suites by Marriott Santee are two other good choices in the immediate area.

What's the best golf hotel in Santee?

Holiday Inn Santee, an IHG Hotel is a top hotel that has an adjacent golf course and features free WiFi. Another good choice is Super 8 by Wyndham Santee if you'd like to be close to a golf course while in town. Visit Santee Cooper Country Club or Santee National Golf Club to perfect your golf swing. See more golf hotels in Santee.

What are some accommodations with pools in Santee?

Comfort Inn & Suites Santee is a top hotel with a seasonal outdoor pool, free buffet breakfast, and free WiFi. A couple of other options that offer an onsite pool include Fairfield Inn & Suites by Marriott Santee and Hampton Inn Santee-I-95. View all hotels with pools in Santee.

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