Find luxury hotels in Santee, SC

Pick from 5 Santee Luxury Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.

Comfort Inn & Suites Santee
Lobby
Comfort Inn & Suites Santee
2.5 star property
8.0 out of 10, Very Good, 843 reviews
"Solid no-frills property. Rooms are clean and decent sized. Staff was very friendly"
The price is $125
$139 total
includes taxes & fees
Jun 16 - Jun 17
Comfort Inn & Suites Santee
Baymont by Wyndham Santee
Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi
Baymont by Wyndham Santee
2.5 star property
7.8 out of 10, Good, 1,327 reviews
"I enjoyed my stay at Baymont by Wyndham Santee. The room was nice and clean, the front desk staff were pleasant, easy parking, and quiet. I would definitely recommend this hotel to friends and family."
The price is $80
$89 total
includes taxes & fees
Jun 9 - Jun 10
Baymont by Wyndham Santee
Red Roof Inn Santee
Exterior
Red Roof Inn Santee
2.0 star property
6.4 out of 10, 559 reviews
"Overall it was a great nights stay. Clean and quiet. Will stay there again when I pass through Santee. The other hotels have gone crazy with there rates."
The price is $66
$74 total
includes taxes & fees
Jun 20 - Jun 21
Red Roof Inn Santee
Econo Lodge
Exterior
Econo Lodge
2.0 star property
6.4 out of 10, 302 reviews
"It was great"
The price is $67
$75 total
includes taxes & fees
Jul 8 - Jul 9
Econo Lodge
Rodeway Inn Santee I-95
Lobby
Rodeway Inn Santee I-95
2.0 star property
6.2 out of 10, 498 reviews
"Room #1 - was a little disappointing as it was not totally smoke free. Cigarette smoke could be smelled as soon as you entered. Once the bathroom exhaust fan & A/C fan came on the smoke was stronger. There were also items that were broken or hanging off the wall. Then came a group of people associating near the room, smoking. I then requested to be moved. Room # 2 was excellent no odors, very clean and comfortable. I was very pleased. Staff was professional and helpful. "
The price is $81
$90 total
includes taxes & fees
Jun 20 - Jun 21
Rodeway Inn Santee I-95
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Santee Luxury Hotels information

 

Luxury Hotels in Santee

5

Highest price
$125
Cheapest price
$66
Number of guest reviews
3,527
Total number of hotels in Santee
228

 

Frequently asked questions

Are you looking for a luxury hotel for your stay in Santee?
Let Expedia help you arrange your flight to Columbia Metropolitan Airport (CAE) airport, and then choose from some places to stay that will deliver the luxury you seek. Amenities are important when you plan a trip, so we make it easy to find what you’d like to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can help you find the best luxury hotel experience that Santee has to offer. During your visit, you might want to enjoy the restaurants and coffee shops which Santee is known for.
How many luxury hotels will I be able to find in Santee?
Lie in the lap of luxury during your getaway to Santee in one of Expedia’s 8 luxury hotels.
When can I expect good weather in Santee?
Planning for the weather is an important factor for making your trip to Santee a success, especially when you’re splurging. The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 52°F. Average annual precipitation for Santee is 55 inches.
What's there to see and do in Santee?
Enjoy all that Santee has to offer and visit Santee Cooper Country Club, Santee Outlets, and Santee State Park. If you have a little extra time during your trip, you might want to make a stop at Lake Marion and Santee National Golf Club.

Recent reviews of Santee hotels
Expedia verified reviews

Baymont by Wyndham Santee

Baymont by Wyndham Santee

5/5 Excellent
Good place to spend night
"Nice clean room. It looks like it was recently upgraded. Convenient location for traveling from and to Florida."
A verified traveler stayed at Baymont by Wyndham Santee
Posted 3 days ago
Baymont by Wyndham Santee