Find hotels in Lower Keys, FL from $130

Most hotels are fully refundable. Because flexibility matters.

Save 10% or more on over 100,000 hotels worldwide as a One Key member.

Search over 2.9 million properties and 550 airlines worldwide.

Find properties with these dates

This weekend
Next weekend

Filter by

Popular filters
Popular filters
Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility
Traveler experience
Traveler experience

Compare 769 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Southernmost Beach Resort
4.0 star property
8.2 out of 10, Very Good, (1824)
"Close to southernmost point "
The price is $374
$484 total
includes taxes & fees
May 27 - May 28
Southernmost Beach Resort
Beachside Resort & Residences
4.0 star property
8.4 out of 10, Very Good, (1003)
"well appointed rooms, great staff, great view, great pool, and super laid back !! "
The price is $309
$471 total
includes taxes & fees
May 21 - May 22
Beachside Resort & Residences
NYAH Key West - Adults Only
3.0 star property
7.8 out of 10, Good, (1000)
"Quiet, really close to Duval st and dinning in old town."
The price is $130
$192 total
includes taxes & fees
May 9 - May 10
NYAH Key West - Adults Only
Save an average of 15% on thousands of hotels when you're signed in
The Southernmost Inn - Adults Only
3.0 star property
7.8 out of 10, Good, (1003)
"Great location "
The price is $246
$322 total
includes taxes & fees
May 27 - May 28
The Southernmost Inn - Adults Only
Ocean Key Resort - A Noble House Resort
4.0 star property
9.2 out of 10, Wonderful, (1005)
"Great Place to see it all and the Staff was awesome. "
The price is $419
$534 total
includes taxes & fees
Jun 2 - Jun 3
Ocean Key Resort - A Noble House Resort
Hampton Inn Key West FL
2.5 star property
8.8 out of 10, Excellent, (1088)
"Everything is great"
The price is $259
$325 total
includes taxes & fees
May 5 - May 6
Hampton Inn Key West FL
Silver Palms Inn
3.5 star property
9.2 out of 10, Wonderful, (1007)
"Good location and easy parking. Breakfast omelette is a major bonus. "
The price is $206
$288 total
includes taxes & fees
May 28 - May 29
Silver Palms Inn
The Marker Key West Harbor Resort
4.0 star property
8.8 out of 10, Excellent, (1000)
"Very nice place to stay, conveniently located "
The price is $365
$469 total
includes taxes & fees
May 27 - May 28
The Marker Key West Harbor Resort
Caribbean House
3.0 star property
9.0 out of 10, Wonderful, (76)
"Was close to everything very cute"
The price is $241
$296 total
includes taxes & fees
May 5 - May 6
Caribbean House
Santa Maria Suites
4.0 star property
9.6 out of 10, Exceptional, (1001)
"It was very clean and spacious. Staff were very nice and helpful. "
The price is $479
$584 total
includes taxes & fees
May 28 - May 29
Santa Maria Suites
Paradise Inn Key West - Adults Only
3.5 star property
9.2 out of 10, Wonderful, (1001)
"Cute and spacious. A little older but has a lot of charm! "
The price is $242
$317 total
includes taxes & fees
May 29 - May 30
Paradise Inn Key West - Adults Only
34’ Catamaran Sailboat
9.4 out of 10, Exceptional, (22)
"So glad we stayed here! It is exactly what I was looking for. A unique way to visit Key West. It was nice to open the hatches and have a nice breeze and great view of the stars. He has a nice bathroom with shower in the car port. The host was great with communication and was really cool. Definitely recommend"
34’ Catamaran Sailboat
The Galleria by Brightwild
3.0 star property
7.6 out of 10, Good, (16)
"It was easy very clean comfortable . Small but worth it"
The price is $198
$223 total
includes taxes & fees
May 7 - May 8
The Galleria by Brightwild
The Guesthouses at Southernmost Beach Resort - Adults only
4.0 star property
9.2 out of 10, Wonderful, (876)
"Wonderful daily breakfast and lunch snacks included in resort fee. Lounge chairs and umbrellas included in resort fee. "
The price is $359
$489 total
includes taxes & fees
May 27 - May 28
The Guesthouses at Southernmost Beach Resort - Adults only
The Grand Guesthouse
2.5 star property
9.6 out of 10, Exceptional, (891)
"Nice clean accommodations. Very friendly staff."
The price is $312
$377 total
includes taxes & fees
May 7 - May 8
The Grand Guesthouse
Ridley House - Key West Historic Inns
3.5 star property
9.2 out of 10, Wonderful, (636)
"I had a wonderful stay at the Ridley. My room was a couple of doors down from the main house, in the back of another old house with a deck. I loved doing yoga on the deck in the mornings! A quiet and peaceful way to begin each day. The breakfasts were absolutely incredible! Eggs made to order, banana coconut pancakes, overnight oats, exotic fruits, smoked salmon, etc. They serve iced sangria every afternoon by the pool. I can’t wait to return! "
The price is $390
$480 total
includes taxes & fees
May 13 - May 14
Ridley House - Key West Historic Inns
La Pensione Inn
3.5 star property
8.8 out of 10, Excellent, (1001)
"Our rom was massive with beautiful big bath Old Victorian updated Walkable to Duvall street Excellent breakfast It is on a busy street but wasn’t loud at night Slept well Our room was on second floor. No elevator. Fine for us"
The price is $199
$280 total
includes taxes & fees
May 6 - May 7
La Pensione Inn
Suite Dreams Inn by the Beach
4.0 star property
8.4 out of 10, Very Good, (46)
"The property was off the beaten path, but with easy access to the beach, and walkable to all the interesting sites and experiences of Key West. Nice, private spaces to enjoy your morning coffee or a glass of wine in the evening. Oh, and the delicious Florida oranges were great too!"
Suite Dreams Inn by the Beach
The Inn on Fleming
3.5 star property
9.2 out of 10, Wonderful, (568)
"Charming room. Clean and walking distance away from restaurants and Duval St. "
The price is $289
$325 total
includes taxes & fees
May 5 - May 6
The Inn on Fleming
Hyatt Vacation Club at Sunset Harbor, Key West
3.5 star property
8.4 out of 10, Very Good, (226)
"Great location, will visit again! "
The price is $309
$370 total
includes taxes & fees
May 20 - May 21
Hyatt Vacation Club at Sunset Harbor, Key West
Don't see what you're looking for?
See all available properties in Lower Keys
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Lower Keys

Find the best Lower Keys areas and neighborhoods for the activities you enjoy most. Learn more about Lower Keys

More cheap stays in Lower Keys

Stay near popular Lower Keys attractions

Recent reviews of Lower Keys hotels
Expedia verified reviews