Find 4 Star Hotels in Lower Florida Keys, FL from $159
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Compare Lower Florida Keys 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
Tranquility by Avantstay Close to Duval St w/ BBQ & Shared Pool
Little Palm Island Resort & Spa - A Noble House Resort
Santa Maria Suites
The Gardens Hotel
The Porch on Frances Inn
The Perry Hotel & Marina Key West
Ocean Key Resort - A Noble House Resort
The Guesthouses at Southernmost Beach Resort - Adults only
Oceans Edge Key West Resort, Hotel & Marina
Opal Key Resort & Marina, Key West
Hyatt Centric Key West Resort and Spa
Havana Cabana at Key West
Winslow's Bungalows - Key West Historic Inns
Parrot Key Hotel & Villas
Pier House Resort & Spa
The Marker Key West Harbor Resort
Margaritaville Beach House Key West
The Reach Key West, Curio Collection by Hilton
Beachside Resort & Residences
Suite Dreams Inn by the Beach
Explore similar 5-star hotels
Casa Marina Key West, Curio Collection by Hilton
Lower Florida Keys Four Star Hotel Information
When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Lower Florida Keys, Florida are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Lower Florida Keys 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.
Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Lower Florida Keys. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Lower Florida Keys, Florida, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.
Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Lower Florida Keys hotels offer everything your heart desires.
Lower Florida Keys Hotels by Star Rating
Stay near popular Lower Florida Keys attractions
- Duval Street
- Mallory Square
- Smathers Beach
- Southernmost Point
- South Beach
- Ernest Hemingway Home and Museum
- Fort Zachary Taylor Historic State Park
- Key West Golf Club
- Clarence S. Higgs Memorial Beach Park
- Stock Island Yacht Club & Marina
- Boca Chica Nude Beach
- Harry S. Truman Little White House
- Key West Butterfly and Nature Conservatory
- Key West Lighthouse and Keeper's Quarters Museum
- Florida Keys National Marine Sanctuary
- Calusa Beach
- Mel Fisher Maritime Museum
- Audubon House and Tropical Gardens
- Key West Shipwreck Museum
- Key West Tropical Forest and Botanical Garden
More Accommodation Types in Lower Florida Keys
- Vacation Homes in Lower Florida Keys (697)
- Condo Rentals in Lower Florida Keys (338)
- Apartments in Lower Florida Keys (128)
- Cottages in Lower Florida Keys (76)
- Guest Houses in Lower Florida Keys (24)
- Houseboats in Lower Florida Keys (21)
- Villas in Lower Florida Keys (21)
- B&B in Lower Florida Keys (20)
- Resorts in Lower Florida Keys (12)
- RV Parks in Lower Florida Keys (5)
- Cabin Rentals in Lower Florida Keys (3)
- Motels in Lower Florida Keys (2)
- Aparthotels in Lower Florida Keys (1)
- Hostels in Lower Florida Keys (1)
- Inns in Lower Florida Keys (1)
Explore more hotels
- Cozy, Perfect Conch Cottage!
- Just 20 miles from Key West! Oceanfront, dockage, swimming pool
- Oceanside Paradise: Kayaks, Free WiFi, A/C, Grill, Elevated Deck, 24hr Security
- Old Florida Style, wrap around porch, boat basin for dockage, open water
- THE NEW HIDDEN HAMMOCK RESORT - Pink Cottage Unit #3 Sleeps 4
- Oceanside Paradise in the FL Keys Free Kayaks Bikes Wifi Outdoor BBQ Grill
- Comfortable Waterfront Vacation Rental
- WATERFRONT fresh & cozy 2 bedroom 35 sea wall New UV light air purification
- Canal front, dockage, 2 bedroom, 2 bath
- 3 night minimum! Spectacular Ocean Views!
- Tropical Getaway in Paradise.
- WATERFRONT PARADISE AT VENTURE OUT+4 BIKES & 2-2 SEAT KAYAKS! KING & QUEEN BEDS
- Gulf-front house near Key West with private beach & pool - snowbird-friendly
- Enjoy Caribbean weather. Last minute opening beginning 5/2/24! Enjoy the Keys!
- FL Keys Cottage with Ocean Views - Venture Out Unit 395
- Waterfront Home
- Dock, Htd 80' Pool, Deep Channel, 15 Min To Key West
- SEA SHELL COTTAGE UNIT #2
- Walk to Beach, Open Water View from porch , dock, bikes, kayaks & snorkel gear