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Compare 815 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Courtyard view
Buffalo Airport Hotel
3.0 star property
8.0 out of 10, Very Good, (1980)
"I liked the updated outlets on the wall "
The price is $104
$119 total
includes taxes & fees
May 20 - May 21
Buffalo Airport Hotel
Indoor pool
M Hotel Buffalo
3.5 star property
7.0 out of 10, Good, (681)
"The hotel is accessible to shopping, highways and the airport."
The price is $91
$104 total
includes taxes & fees
May 19 - May 20
M Hotel Buffalo
Terrace/patio
Hyatt Regency Buffalo / Hotel and Conference Center
3.5 star property
7.6 out of 10, Good, (1106)
"Personal parking was right across an unbusy street and didn't need to pay for it through the hotel. The lobby was beautiful, rooms were simple and well appointed. A vent in the bathroom would have been nice, but not a deal breaker. Overall, a very nice stay."
The price is $164
$187 total
includes taxes & fees
May 27 - May 28
Hyatt Regency Buffalo / Hotel and Conference Center
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Exterior detail
Hilton Garden Inn Buffalo Downtown
3.0 star property
8.6 out of 10, Excellent, (1001)
"Facility clean and updated. However, windows need heavy drapes as only sheer lightweight ones in place. Not an issue if you are getting up at daybreak. Just don't plan on sleeping in. Staff very good. Location very convenient to courts/government/banks/library/offices. Very little retail left in DT Buffalo anymore. "
The price is $156
$180 total
includes taxes & fees
May 28 - May 29
Hilton Garden Inn Buffalo Downtown
Lobby
Wyndham Garden Buffalo Downtown
3.0 star property
9.0 out of 10, Wonderful, (1002)
"Not in a great area. If not for the hospital I would say the area is rather bad section of Buffalo "
The price is $132
$150 total
includes taxes & fees
May 28 - May 29
Wyndham Garden Buffalo Downtown
Terrace/patio
Home2 Suites by Hilton Amherst Buffalo
3.0 star property
8.8 out of 10, Excellent, (1001)
"The breakfast options could have been more appetizing."
The price is $143
$163 total
includes taxes & fees
Jun 2 - Jun 3
Home2 Suites by Hilton Amherst Buffalo
Reception
Garden Place Hotel
3.5 star property
7.6 out of 10, Good, (1385)
"Nice hotel, big rooms. Really enjoy my time there. "
The price is $91
$104 total
includes taxes & fees
May 28 - May 29
Garden Place Hotel
Indoor pool
Sleep Inn
2.5 star property
8.6 out of 10, Excellent, (1000)
"everything was perfect, i will come back"
The price is $102
$116 total
includes taxes & fees
Jun 2 - Jun 3
Sleep Inn
Interior entrance
Quality Inn Near Walden Galleria Mall
2.5 star property
8.2 out of 10, Very Good, (1000)
"stayed there for one night, good location"
The price is $103
$267 total
includes taxes & fees
May 20 - May 21
Quality Inn Near Walden Galleria Mall
Exterior
Hyatt Place Buffalo/Amherst
3.0 star property
9.2 out of 10, Wonderful, (1005)
"The property was well kept. The pool was clean and the towels were well stocked. The hotel was well situated in a beautiful area. "
The price is $127
$144 total
includes taxes & fees
May 20 - May 21
Hyatt Place Buffalo/Amherst
Free daily continental breakfast
Hampton Inn Buffalo - Amherst, NY
2.5 star property
9.4 out of 10, Exceptional, (1320)
"Nice clean hotel in quiet area"
The price is $118
$134 total
includes taxes & fees
May 29 - May 30
Hampton Inn Buffalo - Amherst, NY
Aerial view
Fairbridge Inn Express Buffalo Airport Williamsville
2.0 star property
5.2 out of 10, (1001)
"The front desk clerk Melissa was a nice woman and helped my brother and his friend check in smoothly. The room wasn't the best in terms of cleanliness, but hey u get what u pay for right. The customer service here was very good and we will come again anytime we upstate. The area has alot of food spots also so no wasting money on Uber eats"
The price is $46
$52 total
includes taxes & fees
May 19 - May 20
Fairbridge Inn Express Buffalo Airport Williamsville
Lobby
La Quinta Inn & Suites by Wyndham Buffalo Amherst
2.5 star property
8.2 out of 10, Very Good, (1381)
"Th hotel was very clean and comfortable. "
The price is $101
$115 total
includes taxes & fees
May 20 - May 21
La Quinta Inn & Suites by Wyndham Buffalo Amherst
Exterior
Sleep Inn & Suites Buffalo Airport
2.5 star property
8.2 out of 10, Very Good, (1115)
"I was in the hotel for a great deal of my stay. Lovely staff, wonderful stay."
The price is $103
$117 total
includes taxes & fees
May 20 - May 21
Sleep Inn & Suites Buffalo Airport
Indoor pool
Hilton Garden Inn Buffalo Airport
3.0 star property
8.8 out of 10, Excellent, (1001)
"Staff are very nice and helpful. Used the restaurant once it was okay, but nothing special And on the expensive side but convenient after i returned my rental car The drivers to and from from the airport was so nice and friendly and helpful The carpets are really dirty in the bedroom and the grab handle in the shower/Bath tub Is located right next to the toilet. So it was really hard to use it to get In&Out. It's poorly placed and I felt it was a safety issue. I have some balance issues Due to...
The price is $152
$173 total
includes taxes & fees
May 26 - May 27
Hilton Garden Inn Buffalo Airport
Interior entrance
Motel 6 Amherst, NY - Buffalo
2.0 star property
6.6 out of 10, (1000)
"The room was great"
The price is $66
$76 total
includes taxes & fees
Jun 2 - Jun 3
Motel 6 Amherst, NY - Buffalo
2 bars/lounges
Curtiss Hotel, Ascend Hotel Collection
5.0 star property
9.2 out of 10, Wonderful, (1002)
"Excellent service from the minute I drove into the parking lot. Check in, food service etc. clean gorgeous room"
The price is $219
$249 total
includes taxes & fees
May 19 - May 20
Curtiss Hotel, Ascend Hotel Collection
Exterior
Hampton Inn & Suites Buffalo Downtown
2.5 star property
8.8 out of 10, Excellent, (1003)
"The suites are spectacular with beautiful views of the downtown Buffalo architecture and Lake Erie. The bathroom was huge and luxurious!"
The price is $169
$192 total
includes taxes & fees
May 28 - May 29
Hampton Inn & Suites Buffalo Downtown
Terrace/patio
Buffalo Marriott Niagara
3.5 star property
8.0 out of 10, Very Good, (1004)
"Amazing staff."
The price is $118
$134 total
includes taxes & fees
May 20 - May 21
Buffalo Marriott Niagara
Lobby lounge
Red Roof Inn Buffalo - Niagara Airport
2.0 star property
8.0 out of 10, Very Good, (998)
"It was wonderful and we were serviced to the utmost. The only thing I would recommend is if you have scent allergies please phone ahead to make sure they do not spray the room with any cleaners, as they were pretty strong to breathe."
The price is $80
$91 total
includes taxes & fees
May 28 - May 29
Red Roof Inn Buffalo - Niagara Airport
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See all available properties in Depew
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Depew Travel Info

Number of reviews
6,441
Accommodation
815 hotels
Highest price
$219
Lowest price
$46
Reasons to visit
Buffalo Zoo, Buffalo Museum of Science and Albright - Knox Art Gallery
Hotels with dining
16
Hotels with family-friendly amenities
14

Frequently asked questions

What's the best place for a stay in Depew?

Located 2.6 mi (4.2 km) from the heart of Depew, Sleep Inn & Suites Buffalo Airport is a top choice for your stay based on our traveler data. Two other choices for your visit to the area are Niagara Riverside Resort, BW Premier Collection and Hampton Inn Buffalo - Amherst, NY. See all available top hotels, or vacation rentals in Depew.

What's the top vacation rental in Depew?

4 bedrooms & 3 bathrooms | Entire Home For Families 🏠: This vacation home rental outside of Depew has air-conditioning and a Smart TV to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. See all vacation rentals in Depew.

If I need to cancel my hotel reservation in Depew, will I receive a refund?

Yes! Most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Depew.

Where can I learn more about changing or cancelling my trip to Depew?

For more information about picking new dates or cancelling your trip to Depew, click here.

What's the best budget-friendly hotel in Depew?

Based on our traveler reviews, Pink Fountain Motor Inn is a top choice for a less expensive stay. View all budget hotels in Depew.

What's the best hotel for a couple going to Depew?

Pink Fountain Motor Inn is a favorite property for couples, and features cable TV and free WiFi. See all romantic hotels in Depew.

What are some accommodations with pools in Depew?

Niagara Riverside Resort, BW Premier Collection: Hotel located near Fashion Outlets of Niagara Falls. Offers a health club, an indoor pool, and complimentary wireless internet access. Hampton Inn Buffalo - Amherst, NY and Holiday Inn Express Grand Island - Niagara Falls, an IHG Hotel are a couple of other choices that feature an onsite pool. View all hotels with pools in Depew.

What is the best spa hotel in Depew?

Pink Fountain Motor Inn is a top spa hotel with 14 rooms, free WiFi, and free self parking. Kick back and relax in the spa tub.

What's the best place to stay near Buffalo Niagara International Airport (BUF)?

Days Hotel by Wyndham Buffalo Airport is a popular 3-star hotel featuring free breakfast and a restaurant. It's located a short 0.3 mi (0.5 km) from Buffalo Niagara Intl. Airport. Other places to stay within close proximity to the airport include Hilton Garden Inn Buffalo Airport and Courtyard Buffalo Airport.

What is staying in Depew like?

Visitors can enjoy all that Depew has to offer including the shopping, restaurants, and sporting events. Tourists can also enjoy so much more including its waterfalls. In Depew, there are 11 hotels and other accommodations to choose from. Find out more about Depew.

What are the top places to visit in Depew?

Places to visit in the wider area include Walden Galleria Mall, Samuel’s Grande Manor, and Glen Falls. You'll also find Eastern Hills Mall and Broadway Market in the area. Check out what more to see and do in Expedia's Depew guide.

How should I get around Depew?

To see more of the larger area, ride aboard one of the trains from Buffalo-Depew Station. If you want to venture out around the area, you may want a rental car in Depew for your journey.

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