Find all hotels by Independent in Clayton, MO from $57
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Compare rooms and suites by Independent in Clayton with rates, reviews, and availability. Most hotels are fully refundable.
The Charles F. Knight Center
The Charles F. Knight Center
9.2 out of 10, Wonderful, (135)
The price is $179
$206 total
includes taxes & fees
May 19 - May 20
Moonrise Hotel
Moonrise Hotel
9.0 out of 10, Wonderful, (1358)
The price is $159
$189 total
includes taxes & fees
May 27 - May 28
Clayton Plaza Hotel & Extended Stay
Clayton Plaza Hotel & Extended Stay
8.8 out of 10, Excellent, (2860)
The price is $114
$133 total
includes taxes & fees
Jun 9 - Jun 10
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Angad Arts Hotel
Angad Arts Hotel
8.8 out of 10, Excellent, (1027)
The price is $135
$159 total
includes taxes & fees
Jun 3 - Jun 4
The Wildwood Hotel
The Wildwood Hotel
8.8 out of 10, Excellent, (1281)
The price is $94
$114 total
includes taxes & fees
May 28 - May 29
Missouri Athletic Club
Missouri Athletic Club
8.6 out of 10, Excellent, (1000)
The price is $128
$150 total
includes taxes & fees
May 23 - May 24
The Last Hotel
The Last Hotel
8.4 out of 10, Very Good, (1003)
The price is $152
$178 total
includes taxes & fees
May 23 - May 24
The Cheshire
The Cheshire
8.4 out of 10, Very Good, (1001)
The price is $161
$191 total
includes taxes & fees
May 20 - May 21
Casino Queen Hotel
Casino Queen Hotel
8.0 out of 10, Very Good, (1431)
The price is $99
$115 total
includes taxes & fees
May 28 - May 29
Forest Park Hotel by MDR
Forest Park Hotel by MDR
7.2 out of 10, Good, (405)
The price is $108
$128 total
includes taxes & fees
May 19 - May 20
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent reviews of Clayton hotelsExpedia verified reviews
5/5 Excellent
"Such a lovely, art-filled establishment with impressive top-notch dining options for breakfast, lunch, & dinner. Cozy quaint living space with an incredible selection of aromatic toiletries. Convenient valet service with competitive rates for city-street parking and delightful staff! I will definitely be staying at the 21c hotels in the future! "
A verified traveler from Pleasant Valley stayed at 21C Museum Hotel St Louis
Posted 17 hours ago
Hotels in Clayton Neighborhoods
Hotels near popular St. Louis Attractions
- Hotels near Chapel of St. Timothy And St. Titus
- Hotels near St. Louis Union Station
- Hotels near Busch Stadium
- Hotels near Gateway Arch
- Hotels near St. Louis Zoo
- Hotels near Enterprise Center
- Hotels near Washington University in St. Louis
- Hotels near Forest Park
- Hotels near Hollywood Casino Amphitheatre
- Hotels near City Museum
More Hotel Options in Clayton
- Boutique Hotels (3)
- Business Hotels (5)
- Cheap Hotels (3)
- Family Hotels (5)
- Golf Hotels (5)
- Historic Hotels (5)
- Hotel Wedding Venues (4)
- Hotel with a Concierge (4)
- Hotels & Resorts for Couples (5)
- Hotels with Air Conditioning (5)
- Hotels with Balconies (3)
- Hotels with Bars (5)
- Hotels with Connecting Rooms (5)
- Hotels with Free Airport Shuttle (1)
- Hotels with Free Breakfast (4)
- Hotels with Free Parking (2)
- Hotels with Free Wifi (4)
- Hotels with Hot Tubs (4)
- Hotels with Laundry Facilities (4)
- Hotels with Restaurants (5)
- Hotels with Room Service (4)
- Hotels with a Gym (4)
- Hotels with a Pool (4)
- Hotels with a View (4)
- Hotels with an Indoor Pool (3)
- Hotels with an Outdoor Pool (4)
- Luxury Hotels (4)
- Non-Smoking Hotels (3)
- Pet-friendly Hotels (3)
- Quiet Resorts & Hotels (1)
- Resorts & Hotels with Spas (3)
- Romantic Hotels (4)
Explore more hotels
- Best Western St. Louis-Kirkwood Route 66
- Days Inn and Suites by Wyndham St. Louis/Westport Plaza
- Hampton Inn St. Louis-Downtown (At the Gateway Arch)
- Sonesta ES Suites St. Louis - Chesterfield
- Hilton St. Louis at the Ballpark
- Casino Queen Hotel
- 21C Museum Hotel St Louis
- Moonrise Hotel
- Angad Arts Hotel
- Hilton St. Louis Airport
- La Quinta Inn & Suites by Wyndham St. Louis Westport
- Live by Loews - St.Louis
- Wingate by Wyndham St. Louis Airport
- Forest Park Hotel by MDR
- Drury Inn & Suites St. Louis Union Station
- Renaissance St. Louis Airport Hotel
- River City Casino & Hotel
- The Wildwood Hotel
- Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
- Aviator Hotel & Suites South I-55, BW Signature Collection
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