Find all hotels by Hilton Hotels in Clayton, MO from $121
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Compare rooms and suites by Hilton Hotels in Clayton with rates, reviews, and availability. Most hotels are fully refundable.
The Pennywell St.Louis Downtown, a Hilton Hotel
The Pennywell St.Louis Downtown, a Hilton Hotel
8.8 out of 10, Excellent, (359)
The price is $131
$154 total
includes taxes & fees
May 27 - May 28
Hilton St. Louis Frontenac
Hilton St. Louis Frontenac
8.6 out of 10, Excellent, (1001)
The price is $135
$157 total
includes taxes & fees
May 26 - May 27
Hilton St. Louis Airport
Hilton St. Louis Airport
7.6 out of 10, Good, (1001)
The price is $121
$142 total
includes taxes & fees
May 20 - May 21
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Hilton St. Louis at the Ballpark
Hilton St. Louis at the Ballpark
7.6 out of 10, Good, (1011)
The price is $178
$213 total
includes taxes & fees
May 28 - May 29
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent reviews of Clayton hotelsExpedia verified reviews
5/5 Excellent
"Such a lovely, art-filled establishment with impressive top-notch dining options for breakfast, lunch, & dinner. Cozy quaint living space with an incredible selection of aromatic toiletries. Convenient valet service with competitive rates for city-street parking and delightful staff! I will definitely be staying at the 21c hotels in the future! "
A verified traveler from Pleasant Valley stayed at 21C Museum Hotel St Louis
Posted 18 hours ago
Hotels in Clayton Neighborhoods
Hotels near popular St. Louis Attractions
- Hotels near Chapel of St. Timothy And St. Titus
- Hotels near St. Louis Union Station
- Hotels near Busch Stadium
- Hotels near Gateway Arch
- Hotels near St. Louis Zoo
- Hotels near Enterprise Center
- Hotels near Washington University in St. Louis
- Hotels near Forest Park
- Hotels near Hollywood Casino Amphitheatre
- Hotels near City Museum
More Hotel Options in Clayton
- Boutique Hotels (3)
- Business Hotels (5)
- Cheap Hotels (3)
- Family Hotels (5)
- Golf Hotels (5)
- Historic Hotels (5)
- Hotel Wedding Venues (4)
- Hotel with a Concierge (4)
- Hotels & Resorts for Couples (5)
- Hotels with Air Conditioning (5)
- Hotels with Balconies (3)
- Hotels with Bars (5)
- Hotels with Connecting Rooms (5)
- Hotels with Free Airport Shuttle (1)
- Hotels with Free Breakfast (4)
- Hotels with Free Parking (2)
- Hotels with Free Wifi (4)
- Hotels with Hot Tubs (4)
- Hotels with Laundry Facilities (4)
- Hotels with Restaurants (5)
- Hotels with Room Service (4)
- Hotels with a Gym (4)
- Hotels with a Pool (4)
- Hotels with a View (4)
- Hotels with an Indoor Pool (3)
- Hotels with an Outdoor Pool (4)
- Luxury Hotels (4)
- Non-Smoking Hotels (3)
- Pet-friendly Hotels (3)
- Quiet Resorts & Hotels (1)
- Resorts & Hotels with Spas (3)
- Romantic Hotels (4)
Explore more hotels
- Best Western St. Louis-Kirkwood Route 66
- Days Inn and Suites by Wyndham St. Louis/Westport Plaza
- Hampton Inn St. Louis-Downtown (At the Gateway Arch)
- Sonesta ES Suites St. Louis - Chesterfield
- Hilton St. Louis at the Ballpark
- Casino Queen Hotel
- 21C Museum Hotel St Louis
- Moonrise Hotel
- Angad Arts Hotel
- Hilton St. Louis Airport
- La Quinta Inn & Suites by Wyndham St. Louis Westport
- Live by Loews - St.Louis
- Wingate by Wyndham St. Louis Airport
- Forest Park Hotel by MDR
- Drury Inn & Suites St. Louis Union Station
- Renaissance St. Louis Airport Hotel
- River City Casino & Hotel
- The Wildwood Hotel
- Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
- Aviator Hotel & Suites South I-55, BW Signature Collection