Sicily Luxury Vacations

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Top Luxury vacation packages in Sicily

Price found within the past 48 hours. Click for updated prices.
NH Collection Taormina
Atlantis Bay - VRetreats
La Plage Resort
Eurostars Centrale Palace
Grand Hotel et Des Palmes
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5* Luxury vacations in Sicily

Price found within the past 48 hours. Click for updated prices.
Grand Hotel et Des Palmes
Atlantis Bay - VRetreats
The Ashbee Hotel
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3 Night Luxury vacations in Sicily

Price found within the past 48 hours. Click for updated prices.
Almar Giardino di Costanza Resort & Spa
Atlantis Bay - VRetreats
Therasia Resort Sea & Spa - The Leading Hotels of the World
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4 Night Luxury vacations in Sicily

Price found within the past 48 hours. Click for updated prices.
Palazzo Brunaccini
Grand Hotel et Des Palmes
The Ashbee Hotel
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All you need to know about luxury vacations in Sicily

What can I expect from a luxury Sicily vacation?

Luxury means the very finest of the things you enjoy most. Indulge your every waking moment—and restful night—with a luxury Sicily vacation. Sip handcrafted cocktails by an infinity pool, sink into bliss at a full-service spa with a massage cabana on the beach, and chat, cheers, and laugh through exquisite breakfasts, lunches, and dinners with spectacular views. 

How can I find all-inclusive luxury vacation packages in Sicily?

By refining your filters, the most opulent all-inclusive vacation packages will appear before your eyes. Check the 5* filter to find truly sensational stays. You barely need to lift a finger. 

Can I book a cheap Sicily luxury vacation?

Affordable luxury is only ever a few clicks away. Enter your travel dates and sort the grandiose getaways on offer by price to see the most fiscally friendly retreats first. Filter by budget, too, to find your perfect balance of luxury. Right now, luxury vacations start at $765. Prices and availability are subject to change. Additional terms may apply.

How can I book a luxury family vacation in Sicily?

Tailor your luxury family escape by checking the filters that set the whole family’s hearts a-flutter. Whether that’s wet and wild water parks, heavenly hot tubs, or the kid-quieting magic of free Wi-Fi. 

Can I book a package in Sicily with a luxury vacation home?

A private paradise is true luxury! Filter by property type for houses, villas, and apartments. For an amazingly affordable all-in-one luxury experience, book your accommodation, airfare, and car rental as a package.   

How can I find the best luxury vacation deals in Sicily?

Find absolute delight in the dropdown! Simply sort your tempting search results by deals to find that lean-budget luxury. For a budget conscious stay, consider booking a stay away from big cities or outside the peak months.

Can I book a luxury holiday in Sicily with free cancellation and/or flexible dates?

Freedom and flexibility are the greatest luxuries of all. Get both when you filter by payment option and book a trip with free cancellation or on a buy now, pay later plan. 

Why should I book my luxury trip to Sicily with Expedia?

A luxurious trip follows a stress-free booking experience. Find, build, and book the most glorious of getaways in seconds—with ATOL protection for added peace of mind.

Top Luxury Sicily Hotels

San Domenico Palace, Taormina, A Four Seasons Hotel
San Domenico Palace, Taormina, A Four Seasons Hotel
5 out of 5
PIAZZA SAN DOMENICO, 5, Taormina, ME
  • 5 hours drive from Mondello Beach
The price is $2,805 per night from Apr 29 to Apr 30
$2,805
includes taxes & fees
$2,540 per night
Apr 29 - Apr 30
Choose luxury at San Domenico Palace, Taormina, A Four Seasons Hotel, where you can enjoy amenities like Champagne service, massage services, and more. Deluxe ...
9.2/10 Wonderful! (264 reviews)
Dream long weekend
"Everything was perfect. The service could not be faulted and the property is incredible. Dont think about it and just book here"

Reviewed on Apr 21, 2025

San Domenico Palace, Taormina, A Four Seasons Hotel
Grand Hotel Des Ètrangers
Grand Hotel Des Ètrangers
5 out of 5
Passeggio Adorno 10/12, Syracuse, SR
  • 6 hours drive from Mondello Beach
The price is $552 per night from May 27 to May 28
$552
includes taxes & fees
$491 per night
May 27 - May 28
Grand Hotel Des Ètrangers delivers luxe lodging where you'll enjoy designer toiletries and more. The spa, outdoor pool, and poolside bar are just some of the ...
9.4/10 Exceptional! (39 reviews)
"X"

Reviewed on Apr 19, 2025

Grand Hotel Des Ètrangers
Grand Hotel Ortigia Siracusa
Grand Hotel Ortigia Siracusa
5 out of 5
Viale Mazzini, 12, Syracuse, SR
  • 6 hours drive from Mondello Beach
The price is $323 per night from Apr 30 to May 1
$323
includes taxes & fees
$283 per night
Apr 30 - May 1
Grand Hotel Ortigia Siracusa is one of the Syracuse luxury 5-star beach properties where you can treat yourself to Champagne service, plush bedding, and more. ...
8.8/10 Excellent! (534 reviews)
"What a beautiful property transporting you back in time. Excellent hotel staff kindly arranged a breakfast box to go as we were leaving early. We did not even ask for it. How generous and kind. We shall return."

Reviewed on Apr 14, 2025

Grand Hotel Ortigia Siracusa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More vacations you might like

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.