$271 Cheap Flights from Santa Cruz (VVI) to Santiago (SCL)

View $271 flight on Tue, Aug 26, 2025Opens in a new window

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Find available prices by choosing your travel dates.

Cheap Flights from Santa Cruz to Santiago (VVI-SCL)

Prices were available within the past 7 days and start at $271 for one-way flights and $467 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aerolineas Argentinas
Sat, Jun 14 - Mon, Jun 30
VVI
Santa Cruz
SCL
Santiago
$467 Roundtrip, found 12 hours ago
$467
Roundtrip
found 12 hours ago
Select Aerolineas Argentinas flight, departing Sat, Jun 14 from Santa Cruz to Santiago, returning Mon, Jun 30, priced at $467 found 12 hours ago
Aerolineas Argentinas
Tue, Dec 2 - Thu, Dec 25
VVI
Santa Cruz
SCL
Santiago
$469 Roundtrip, found 11 hours ago
$469
Roundtrip
found 11 hours ago
Select Aerolineas Argentinas flight, departing Tue, Dec 2 from Santa Cruz to Santiago, returning Thu, Dec 25, priced at $469 found 11 hours ago
Aerolineas Argentinas
Sat, May 3 - Mon, May 19
VVI
Santa Cruz
SCL
Santiago
$470 Roundtrip, found 6 hours ago
$470
Roundtrip
found 6 hours ago
Select Aerolineas Argentinas flight, departing Sat, May 3 from Santa Cruz to Santiago, returning Mon, May 19, priced at $470 found 6 hours ago
Aerolineas Argentinas
Sat, May 24 - Mon, May 26
VVI
Santa Cruz
SCL
Santiago
$477 Roundtrip, found 12 hours ago
$477
Roundtrip
found 12 hours ago
Select Aerolineas Argentinas flight, departing Sat, May 24 from Santa Cruz to Santiago, returning Mon, May 26, priced at $477 found 12 hours ago
Aerolineas Argentinas
Tue, Jun 24 - Sun, Jul 13
VVI
Santa Cruz
SCL
Santiago
$478 Roundtrip, found 2 days ago
$478
Roundtrip
found 2 days ago
Select Aerolineas Argentinas flight, departing Tue, Jun 24 from Santa Cruz to Santiago, returning Sun, Jul 13, priced at $478 found 2 days ago
Aerolineas Argentinas
Sat, May 3 - Fri, May 16
VVI
Santa Cruz
SCL
Santiago
$480 Roundtrip, found 6 hours ago
$480
Roundtrip
found 6 hours ago
Select Aerolineas Argentinas flight, departing Sat, May 3 from Santa Cruz to Santiago, returning Fri, May 16, priced at $480 found 6 hours ago
Aerolineas Argentinas
Sat, Jun 14 - Thu, Jul 3
VVI
Santa Cruz
SCL
Santiago
$480 Roundtrip, found 6 days ago
$480
Roundtrip
found 6 days ago
Select Aerolineas Argentinas flight, departing Sat, Jun 14 from Santa Cruz to Santiago, returning Thu, Jul 3, priced at $480 found 6 days ago
LATAM Airlines Group
Wed, Dec 3 - Fri, Dec 26
VVI
Santa Cruz
SCL
Santiago
$486 Roundtrip, found 11 hours ago
$486
Roundtrip
found 11 hours ago
Select LATAM Airlines Group flight, departing Wed, Dec 3 from Santa Cruz to Santiago, returning Fri, Dec 26, priced at $486 found 11 hours ago
avianca
Thu, Jun 12 - Sat, Jun 14
VVI
Santa Cruz
SCL
Santiago
$1,301 Roundtrip, found 12 hours ago
$1,301
Roundtrip
found 12 hours ago
Select avianca flight, departing Thu, Jun 12 from Santa Cruz to Santiago, returning Sat, Jun 14, priced at $1,301 found 12 hours ago
Copa
Thu, Jun 12 - Sat, Jun 28
VVI
Santa Cruz
SCL
Santiago
$1,359 Roundtrip, found 2 days ago
$1,359
Roundtrip
found 2 days ago
Select Copa flight, departing Thu, Jun 12 from Santa Cruz to Santiago, returning Sat, Jun 28, priced at $1,359 found 2 days ago
Flights from Santa Cruz (VVI) to Santiago (SCL)
Origin airport
Viru Viru Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
Aerolineas Argentinas, Copa, LATAM Airlines Group, avianca
Roundtrip price
$467
Distance
1187 mi

Santa Cruz to Santiago Flights

The cheapest times to fly from Santa Cruz to Santiago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santa Cruz to Santiago are during the month of June. You can find some of the cheapest flights from Santa Cruz to Santiago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santa Cruz to Santiago

Sunday is one of the best days to book for cheap flights from Santa Cruz to Santiago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santa Cruz to Santiago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santa Cruz to Santiago in 2025. You can also book with separate airlines for your outbound and return journeys, from $271 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santa Cruz to Santiago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santa Cruz to Santiago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Viru Viru Intl. Airport (VVI) to Arturo Merino Benitez Airport (SCL) cost?
Cheap round-trip fares from Viru Viru Intl. Airport (VVI) to Arturo Merino Benitez Airport (SCL) start at $593. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a LATAM Airlines Group flight leaving VVI on May 21 2025 and touching down at SCL. The price was last updated on April 26 2025 and has not changed since.
What is the cheapest month to fly from VVI to SCL?
The cheapest flights from VVI to SCL are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Viru Viru Intl. Airport (VVI) to Arturo Merino Benitez Airport (SCL)?
Take a nonstop flight with LATAM Airlines and travel straight from Viru Viru Intl. Airport (VVI) to Arturo Merino Benitez Airport (SCL).
What is the cheapest airline that flies from VVI to SCL?
Fly from VVI to SCL with LATAM Airlines Group. This airline currently offers the cheapest one-way ticket for this route, starting from $333. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from VVI on June 1 2025. Prices were last updated on April 26 2025 and have not changed since.
How many flights per day from Viru Viru Intl. Airport (VVI) to Arturo Merino Benitez Airport (SCL)?
On average, you can pick from 4 direct flights each week from Viru Viru Intl. Airport (VVI) to Arturo Merino Benitez Airport (SCL). For greater flexibility, consider taking a flight with a layover. Simply enter your dates on Expedia and then set the filters to include one or two stops.
What are the most popular departure times for flights from Viru Viru Intl. Airport (VVI) to Arturo Merino Benitez Airport (SCL)?
More travelers fly between VVI and SCL at 11 AM than at any other time. Looking to skip the crowds? Try choosing a quieter departure window and you could save on your fare as well.
What day of the week has the most flights from VVI to SCL?
Jet off on a Friday if you’re searching for the best choice of flights from Viru Viru Intl. Airport (VVI) to Arturo Merino Benitez Airport (SCL).
What is the earliest flight from Viru Viru Intl. Airport (VVI) to Arturo Merino Benitez Airport (SCL)?
The first flight of the day taking off from Viru Viru Intl. Airport (VVI) is at around 7:26AM UTC-4. Board this flight and you’ll arrive at Arturo Merino Benitez Airport (SCL) at approximately 11:32AM UTC-3. The total travel time is 3h 6m.
How long does it take to fly from Viru Viru Intl. Airport (VVI) to Arturo Merino Benitez Airport (SCL)?
The average flight duration from VVI to SCL is 3 hours and 6 minutes, covering a distance of 1,200 mi.
What is the best time to fly from Viru Viru Intl. Airport (VVI) to Arturo Merino Benitez Airport (SCL)?
To reach Arturo Merino Benitez Airport (SCL) on schedule, opt for a flight that leaves Viru Viru Intl. Airport (VVI) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
What airports do you fly into for Santiago from Viru Viru Intl. Airport (VVI)?
Arturo Merino Benitez Airport (SCL) is the only airport in Santiago with direct flights from Viru Viru Intl. Airport (VVI). Consider your options and find cheap fares on Expedia.
Is it cheaper to buy a plane ticket from Viru Viru Intl. Airport (VVI) to Arturo Merino Benitez Airport (SCL) last-minute?
Holding off until right before your break to book a ticket from VVI to SCL generally means paying more. While you may find some last-minute discounts, they aren’t always guaranteed. Be flexible with your itinerary for a better chance of landing a bargain.
Is it cheaper to book a VVI to SCL flight and hotel package?
Opting for a VVI to SCL flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip all in one place. Pick from our extensive range of stays and then add flights, car rentals and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Viru Viru Intl. Airport (VVI) to Arturo Merino Benitez Airport (SCL)?
In most instances, you’re able to reschedule or cancel your VVI to SCL flight. However, there may be additional charges, especially if you made your booking more than 24 hours ago. Check your itinerary for the airline’s guidelines and fees on flight changes, or if you need further information, go to our Customer Service portal.

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*Available to One Key members.