$104 Cheap Flights from Knoxville (TYS) to Phoenix (PHX)

View $104 flight on Thu, May 29, 2025Opens in a new window
Find available prices by choosing your travel dates.

Cheap Flights from Knoxville to Phoenix (TYS-PHX)

Prices were available within the past 7 days and start at $104 for one-way flights and $218 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Sun, Jun 8 - Wed, Jun 11
TYS
Knoxville
PHX
Phoenix
$218 Roundtrip, found 12 hours ago
$218
Roundtrip
found 12 hours ago
Select Frontier Airlines flight, departing Sun, Jun 8 from Knoxville to Phoenix, returning Wed, Jun 11, priced at $218 found 12 hours ago
Frontier Airlines
Thu, May 29 - Thu, Jun 5
TYS
Knoxville
PHX
Phoenix
$228 Roundtrip, found 6 hours ago
$228
Roundtrip
found 6 hours ago
Select Frontier Airlines flight, departing Thu, May 29 from Knoxville to Phoenix, returning Thu, Jun 5, priced at $228 found 6 hours ago
American Airlines
Sat, May 24 - Wed, May 28
TYS
Knoxville
PHX
Phoenix
$229 Roundtrip, found 1 hour ago
$229
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Sat, May 24 from Knoxville to Phoenix, returning Wed, May 28, priced at $229 found 1 hour ago
American Airlines
Sat, May 24 - Wed, May 28
TYS
Knoxville
PHX
Phoenix
$232 Roundtrip, found 1 hour ago
$232
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Sat, May 24 from Knoxville to Phoenix, returning Wed, May 28, priced at $232 found 1 hour ago
Frontier Airlines
Sun, Jun 8 - Wed, Jun 11
TYS
Knoxville
PHX
Phoenix
$238 Roundtrip, found 5 hours ago
$238
Roundtrip
found 5 hours ago
Select Frontier Airlines flight, departing Sun, Jun 8 from Knoxville to Phoenix, returning Wed, Jun 11, priced at $238 found 5 hours ago
American Airlines
Wed, May 21 - Sun, May 25
TYS
Knoxville
PHX
Phoenix
$240 Roundtrip, found 1 day ago
$240
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, May 21 from Knoxville to Phoenix, returning Sun, May 25, priced at $240 found 1 day ago
American Airlines
Sat, May 24 - Tue, May 27
TYS
Knoxville
PHX
Phoenix
$243 Roundtrip, found 20 hours ago
$243
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Sat, May 24 from Knoxville to Phoenix, returning Tue, May 27, priced at $243 found 20 hours ago
Delta
Wed, May 21 - Sun, May 25
TYS
Knoxville
PHX
Phoenix
$246 Roundtrip, found 1 day ago
$246
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, May 21 from Knoxville to Phoenix, returning Sun, May 25, priced at $246 found 1 day ago
United
Wed, Oct 1 - Wed, Oct 8
TYS
Knoxville
PHX
Phoenix
$251 Roundtrip, found 1 hour ago
$251
Roundtrip
found 1 hour ago
Select United flight, departing Wed, Oct 1 from Knoxville to Phoenix, returning Wed, Oct 8, priced at $251 found 1 hour ago
Alaska Airlines
Tue, Sep 9 - Sat, Sep 13
TYS
Knoxville
PHX
Phoenix
$351 Roundtrip, found 5 days ago
$351
Roundtrip
found 5 days ago
Select Alaska Airlines flight, departing Tue, Sep 9 from Knoxville to Phoenix, returning Sat, Sep 13, priced at $351 found 5 days ago
Flights from Knoxville (TYS) to Phoenix (PHX)
Origin airport
McGhee Tyson
Destination airport
Sky Harbor Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, Frontier Airlines, United
Roundtrip price
$218
Distance
1596 mi

Knoxville to Phoenix Flights

The cheapest times to fly from Knoxville to Phoenix

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Knoxville to Phoenix are during the month of June. You can find some of the cheapest flights from Knoxville to Phoenix with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Knoxville to Phoenix

Sunday is one of the best days to book for cheap flights from Knoxville to Phoenix: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Knoxville to Phoenix

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Knoxville to Phoenix in 2025. You can also book with separate airlines for your outbound and return journeys, from $104 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Knoxville to Phoenix flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Knoxville to Phoenix airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from McGhee Tyson Airport (TYS) to Sky Harbor Intl. Airport (PHX) cost?
Discover the latest flight deals from TYS to PHX by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from TYS to PHX?
The cheapest flights from TYS to PHX are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from TYS to PHX?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from TYS to PHX. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from McGhee Tyson Airport (TYS) to Sky Harbor Intl. Airport (PHX)?
On average, McGhee Tyson Airport (TYS) offers 2 direct flights to Sky Harbor Intl. Airport (PHX) weekly. For more choice, take advantage of Expedia’s filter tool to search for flights with a layover. Fit in a quick visit to another location or simply break up your travels.
What are the most popular departure times for flights from McGhee Tyson Airport (TYS) to Sky Harbor Intl. Airport (PHX)?
The 12 PM departures from TYS to PHX are the top choice for many travelers. Prices can be higher for these popular slots. If you want to save on your trip, book during off-peak hours.
What day of the week has the most flights from TYS to PHX?
Fly on a Thursday if you’re looking for the best choice of flights from McGhee Tyson Airport (TYS) to Sky Harbor Intl. Airport (PHX).
What is the earliest flight from McGhee Tyson Airport (TYS) to Sky Harbor Intl. Airport (PHX)?
McGhee Tyson Airport (TYS)’s earliest flight to Sky Harbor Intl. Airport (PHX) departs at approximately 12:33PM UTC-5. With a travel time of 4h 31m, you’ll touch down at around 3:04PM UTC-7.
How long does it take to fly from McGhee Tyson Airport (TYS) to Sky Harbor Intl. Airport (PHX)?
The average flight time from TYS to PHX is 4 hours and 31 minutes, covering a total distance of 1,600 mi.
What is the best time to fly from McGhee Tyson Airport (TYS) to Sky Harbor Intl. Airport (PHX)?
To avoid possible delays on the McGhee Tyson Airport (TYS) to Sky Harbor Intl. Airport (PHX) route, travel before 3 PM. Departures after this time are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
What airports do you fly into for Phoenix from McGhee Tyson Airport (TYS)?
Sky Harbor Intl. Airport (PHX) is the only airport in Phoenix with direct flights from McGhee Tyson Airport (TYS). Check out the options and find affordable fares on Expedia.
Is it cheaper to buy a plane ticket from McGhee Tyson Airport (TYS) to Sky Harbor Intl. Airport (PHX) last-minute?
Last-minute fares from TYS to PHX are usually more expensive. For the lowest rates, start looking for flights ahead of time. That said, if you can play around with your travel dates, you may find a cheap ticket right before your trip.
Is it cheaper to book a TYS to PHX flight and hotel package?
Compared with arranging hotels and flights separately, booking a TYS to PHX flight and hotel package with Expedia could lead to significant savings. Better yet, having everything in one easy place will take the stress out of planning your trip. Just pick your flights and select from our wide range of stays, then customize your trip with extras like tours and car rentals.
Can I cancel or change the date of my flight from McGhee Tyson Airport (TYS) to Sky Harbor Intl. Airport (PHX)?
Usually, it’s possible to reschedule or cancel your TYS to PHX flight. However, if it’s been more than 24 hours since booking, additional charges may apply. Refer to your airline’s policies in your itinerary to see what changes are allowed and if any costs are involved. You’ll also find more information on our Customer Service portal.

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*Available to One Key members.