
Featured airlines
- Plan, book, fly with confidence
- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 30% on select hotels after you book a flight*
Cheap Flights from Knoxville to Minneapolis (TYS-MSP)
Prices were available within the past 7 days and start at $104 for one-way flights and $228 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.










Origin airport | McGhee Tyson |
Destination airport | Minneapolis - St. Paul Intl. |
Airlines serving | American Airlines, Delta, Frontier Airlines, United |
Roundtrip price | $228 |
Distance | 792 mi |
Knoxville to Minneapolis Flights
The cheapest times to fly from Knoxville to Minneapolis
On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Knoxville to Minneapolis are during the month of May. You can find some of the cheapest flights from Knoxville to Minneapolis with Expedia's search tool and vast selection of airlines.
The best time to book a flight from Knoxville to Minneapolis
Sunday is one of the best days to book for cheap flights from Knoxville to Minneapolis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.
How to find cheap round-trip tickets from Knoxville to Minneapolis
Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Knoxville to Minneapolis in 2025. You can also book with separate airlines for your outbound and return journeys, from $104 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.
Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Knoxville to Minneapolis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.
You could also save big by booking one of Expedia's vacation packages. Bundling together your Knoxville to Minneapolis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.
*Terms apply.
Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.
Frequently asked questions
Explore a world of travel with Expedia
Flights
- Flights to Pigeon Forge
- Flights to Boston
- Flights to Nashville
- Flights to San Francisco
- Flights to Orlando
- Flights to Miami
- Flights to San Antonio
- Flights to Las Vegas
- Flights to New York
- Flights to San Diego
- Flights to Fort Lauderdale
- Flights to Key West
- Flights to Houston
- Flights to Los Angeles
- Flights to Honolulu
- Flights to New Orleans
- Flights to Atlanta
- Flights to Chicago
- Flights to Washington
- Flights to Gatlinburg
- Aer Lingus
- Virgin Atlantic
- British Airways
- United
- Frontier Airlines
- Lufthansa
- Brussels Airlines
- Alaska Airlines
- Air Canada
- Delta
- KLM
- Qatar Airways
- Finnair
- Aeromexico
- Air France
- American Airlines
- Flights from DeKalb-Peachtree
- Flights from Greenville-Spartanburg Intl.
- Flights from Pike County - Hatcher Field
- Flights from Asheville Regional
- Flights from Fulton County
- Flights from Virginia Highlands
- Flights from Chattanooga Metropolitan
- Flights from Nashville Intl.
- Flights from Smyrna
- Flights from Tri-Cities Regional
- Flights from Knoxville (TYS) to Denver (DEN)
- Flights from Minneapolis (MSP) to Denver (DEN)
- Flights from Minneapolis (MSP) to New York (NYC)
- Flights from Nashville (BNA) to Los Angeles (LAX)
- Flights from Knoxville (TYS) to Los Angeles (LAX)
- Flights from Minneapolis (MSP) to Los Angeles (LAX)
- Flights from Knoxville (TYS) to Seattle (SEA)
- Flights from Minneapolis (MSP) to Seattle (SEA)
- Flights from Knoxville (TYS) to Boston (BOS)
- Flights from Minneapolis (MSP) to Tampa (TPA)
- Flights from Knoxville (TYS) to Chicago (ORD)
- Flights from Minneapolis (MSP) to Chicago (ORD)
- Flights from Minneapolis (MSP) to Dallas (DFW)
- Flights from Nashville (BNA) to Las Vegas (LAS)
- Flights from Minneapolis (MSP) to Las Vegas (LAS)
- Flights from Memphis (MEM) to Las Vegas (LAS)
- Flights from Knoxville (TYS) to New York (JFK)
- Flights from Nashville (BNA) to Orlando (MCO)
- Flights from Minneapolis (MSP) to Orlando (MCO)
- Flights from Knoxville (TYS) to San Diego (SAN)
- Flights from Knoxville (TYS) to Newark Liberty Intl. Airport (EWR)
- Flights from Minneapolis (MSP) to Honolulu (HNL)
- Flights from Miami (MIA) to Minneapolis (MSP)
- Flights from Fort Lauderdale (FLL) to Minneapolis (MSP)
- Flights from New York (LGA) to Minneapolis (MSP)
- Flights from Boston (BOS) to Minneapolis (MSP)
- Flights from Tampa (TPA) to Minneapolis (MSP)
- Flights from Portland (PDX) to Minneapolis (MSP)
- Flights from Denver (DEN) to Minneapolis (MSP)
- Flights from Seattle (SEA) to Minneapolis (MSP)
- Flights from Phoenix (PHX) to Minneapolis (MSP)
- Flights from Newark Liberty Intl. Airport (EWR) to Minneapolis (MSP)
- Flights from Detroit (DTW) to Minneapolis (MSP)
- Flights from Chicago (ORD) to Minneapolis (MSP)
- Flights from Los Angeles (LAX) to Minneapolis (MSP)
- Flights from Knoxville (TYS) to Fort Lauderdale (FLL)
- Flights from Minneapolis (MSP) to Phoenix (PHX)
- Flights from New York (LGA) to Nashville (BNA)
- Flights from Newark Liberty Intl. Airport (EWR) to Nashville (BNA)
- Flights from Chicago (ORD) to Nashville (BNA)
- Flights from Los Angeles (LAX) to Nashville (BNA)
- Flights from Philadelphia (PHL) to Nashville (BNA)
- Flights from Orlando (MCO) to Nashville (BNA)
- Flights from Boston (BOS) to Nashville (BNA)
- Flights from Dallas (DFW) to Nashville (BNA)
- Flights from Knoxville (TYS) to Miami (MIA)
- Flights from Minneapolis (MSP) to Miami (MIA)
- Flights from Knoxville (TYS) to Orange County (SNA)
- Flights from Knoxville (TYS) to New York (LGA)
- Flights from Minneapolis (MSP) to Fort Myers (RSW)
- Delta Knoxville (TYS) to Denver (DEN) flights
- United Knoxville (TYS) to Los Angeles (LAX) flights
- American Airlines Knoxville (TYS) to Boston (BOS) flights
- Delta Knoxville (TYS) to Chicago (ORD) flights
- Alaska Airlines Knoxville (TYS) to San Diego (SAN) flights
- American Airlines Knoxville (TYS) to Newark Liberty Intl. Airport (EWR) flights
- Alaska Airlines Portland (PDX) to Minneapolis (MSP) flights
- Delta New York (LGA) to Minneapolis (MSP) flights
- Spirit Airlines Detroit (DTW) to Minneapolis (MSP) flights
- Sun Country Airlines Tampa (TPA) to Minneapolis (MSP) flights
- Sun Country Airlines Los Angeles (LAX) to Minneapolis (MSP) flights
- Delta Miami (MIA) to Minneapolis (MSP) flights
- United Newark Liberty Intl. Airport (EWR) to Minneapolis (MSP) flights
- Sun Country Airlines Phoenix (PHX) to Minneapolis (MSP) flights
- American Airlines Chicago (ORD) to Minneapolis (MSP) flights
- Spirit Airlines Fort Lauderdale (FLL) to Minneapolis (MSP) flights
- American Airlines Knoxville (TYS) to Fort Lauderdale (FLL) flights
- American Airlines Knoxville (TYS) to Miami (MIA) flights
- American Airlines Knoxville (TYS) to New York (LGA) flights