$100 Cheap Flights from Knoxville (TYS) to Cleveland (CLE)

Popular airlines from McGhee Tyson Airport (TYS) to Cleveland Hopkins International Airport (CLE)

Find available prices by choosing your travel dates.

Cheap Flights from Knoxville to Cleveland (TYS-CLE)

Prices were available within the past 7 days and start at $100 for one-way flights and $199 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Delta
United
Delta
United
United
United
Delta
American Airlines
Frontier Airlines
Flights from Knoxville (TYS) to Cleveland (CLE)
Origin airport
McGhee Tyson
Destination airport
Hopkins Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, United
Roundtrip price
$198
Distance
404 mi

Knoxville to Cleveland Flights

The cheapest times to fly from Knoxville to Cleveland

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Knoxville to Cleveland are during the month of May. You can find some of the cheapest flights from Knoxville to Cleveland with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Knoxville to Cleveland

Sunday is one of the best days to book for cheap flights from Knoxville to Cleveland: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Knoxville to Cleveland

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Knoxville to Cleveland in 2025. You can also book with separate airlines for your outbound and return journeys, from $100 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Knoxville to Cleveland flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Knoxville to Cleveland airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

Is it cheaper to buy a plane ticket from TYS to CLE last minute?
When it comes to booking your flights, it’s always better to be prepared. While it may be possible to pick up a deal on a Knoxville Airport to Hopkins Intl. Airport (CLE) flight at the last minute, fares usually don’t get cheaper as the departure date nears. Based on flight pricing and demand studies in 2022, we have found that the sweet spot to lock in a domestic flight is between 28 – 35 days in advance. For international flights it’s between three and four months.
What airports do you fly into for Cleveland from Knoxville?
From Knoxville, you can journey to Cleveland via Hopkins Intl. Airport (CLE), Akron-Canton Airport (CAK) and Burke Lakefront Airport (BKL). Find out which airport is best for you before you make a decision. If you pick Hopkins Intl. Airport (CLE), it’s around 10 mi southwest of the city center. Use the dollars you save when booking your fare with Expedia to check out the city’s awesome attractions, such as Progressive Field and Cleveland Browns Stadium.
Can I change the date of my flight from McGhee Tyson Airport (TYS) to Hopkins Intl. Airport (CLE)?
We know life happens and plans change, so Expedia is here to help make amending your journey easy. First, access your Knoxville Airport to Hopkins Intl. Airport (CLE) itinerary through the Expedia Trips portal and check the fare rules regarding changes. If you booked your fare in the last 24 hours, some airlines will allow you to cancel for free and book new flights. If you booked your fare more than 24 hours ago, contact us via our Customer Service portal to see how we can help.

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*Available to One Key members.