$219 Cheap Flights from Tri-Cities (TRI) to San Diego (SAN)

View $219 flight on Fri, May 30, 2025Opens in a new window

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Find available prices by choosing your travel dates.

Cheap Flights from Tri-Cities to San Diego (TRI-SAN)

Prices were available within the past 7 days and start at $219 for one-way flights and $425 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Sat, May 31 - Sat, Jun 7
TRI
Tri-Cities
SAN
San Diego
$425 Roundtrip, just found
$425
Roundtrip
just found
Select Delta flight, departing Sat, May 31 from Tri-Cities to San Diego, returning Sat, Jun 7, priced at $425 just found
Delta
Thu, May 29 - Sat, Jun 7
TRI
Tri-Cities
SAN
San Diego
$431 Roundtrip, just found
$431
Roundtrip
just found
Select Delta flight, departing Thu, May 29 from Tri-Cities to San Diego, returning Sat, Jun 7, priced at $431 just found
American Airlines
Wed, May 28 - Sat, May 31
TRI
Tri-Cities
SAN
San Diego
$431 Roundtrip, found 5 days ago
$431
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, May 28 from Tri-Cities to San Diego, returning Sat, May 31, priced at $431 found 5 days ago
Delta
Tue, Jul 1 - Sat, Jul 5
TRI
Tri-Cities
SAN
San Diego
$437 Roundtrip, found 1 day ago
$437
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Jul 1 from Tri-Cities to San Diego, returning Sat, Jul 5, priced at $437 found 1 day ago
American Airlines
Wed, May 28 - Sat, May 31
TRI
Tri-Cities
SAN
San Diego
$444 Roundtrip, found 5 days ago
$444
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, May 28 from Tri-Cities to San Diego, returning Sat, May 31, priced at $444 found 5 days ago
Delta
Wed, May 28 - Sat, May 31
TRI
Tri-Cities
SAN
San Diego
$444 Roundtrip, found 5 days ago
$444
Roundtrip
found 5 days ago
Select Delta flight, departing Wed, May 28 from Tri-Cities to San Diego, returning Sat, May 31, priced at $444 found 5 days ago
Delta
Sat, May 31 - Mon, Jun 9
TRI
Tri-Cities
SAN
San Diego
$445 Roundtrip, just found
$445
Roundtrip
just found
Select Delta flight, departing Sat, May 31 from Tri-Cities to San Diego, returning Mon, Jun 9, priced at $445 just found
Delta
Sat, Jul 5 - Sat, Jul 26
TRI
Tri-Cities
SAN
San Diego
$451 Roundtrip, found 1 day ago
$451
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Jul 5 from Tri-Cities to San Diego, returning Sat, Jul 26, priced at $451 found 1 day ago
Delta
Tue, Jun 17 - Sat, Jun 21
TRI
Tri-Cities
SAN
San Diego
$455 Roundtrip, found 17 hours ago
$455
Roundtrip
found 17 hours ago
Select Delta flight, departing Tue, Jun 17 from Tri-Cities to San Diego, returning Sat, Jun 21, priced at $455 found 17 hours ago
Delta
Fri, May 30 - Sat, Jun 7
TRI
Tri-Cities
SAN
San Diego
$461 Roundtrip, just found
$461
Roundtrip
just found
Select Delta flight, departing Fri, May 30 from Tri-Cities to San Diego, returning Sat, Jun 7, priced at $461 just found
Flights from Tri-Cities (TRI) to San Diego (SAN)
Origin airport
Tri-Cities Regional
Destination airport
San Diego Intl.
Airlines serving
American Airlines, Delta
Roundtrip price
$425
Distance
1984 mi

Tri-Cities to San Diego Flights

The cheapest times to fly from Tri-Cities to San Diego

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Tri-Cities to San Diego are during the month of May. You can find some of the cheapest flights from Tri-Cities to San Diego with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Tri-Cities to San Diego

Sunday is one of the best days to book for cheap flights from Tri-Cities to San Diego: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Tri-Cities to San Diego

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Tri-Cities to San Diego in 2025. You can also book with separate airlines for your outbound and return journeys, from $219 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Tri-Cities to San Diego flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Tri-Cities to San Diego airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Tri-Cities Regional Airport (TRI) to San Diego Intl. Airport (SAN) cost?
Discover the latest flight deals from TRI to SAN by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from TRI to SAN?
The cheapest flights from TRI to SAN are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from TRI to SAN?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from TRI to SAN. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Tri-Cities Regional Airport (TRI) to San Diego Intl. Airport (SAN)?
There are no daily nonstop flights from Tri-Cities Regional Airport (TRI) to San Diego Intl. Airport (SAN). But you can book flights with layovers. Filter your search results on Expedia to include one or two stops, and you’ll be soaring above the clouds in no time.
What day of the week has the most flights from TRI to SAN?
You’ll generally find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Tri-Cities Regional Airport (TRI) to San Diego Intl. Airport (SAN)?
To avoid possible delays on the Tri-Cities Regional Airport (TRI) to San Diego Intl. Airport (SAN) route, aim to travel before 3 PM. Later flights have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Tri-Cities Regional Airport (TRI) to San Diego Intl. Airport (SAN) last-minute?
Booking your flight from TRI to SAN just before your trip is generally more expensive. However, if there’s some wiggle room with your travel times and dates, you could snag a cheap last-minute fare.
Is it cheaper to book a TRI to SAN flight and hotel package?
Securing a TRI to SAN flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip all in one place. Choose from our impressive range of accommodations and then add activities, flights and car rentals to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Tri-Cities Regional Airport (TRI) to San Diego Intl. Airport (SAN)?
If you booked your TRI to SAN flight in the last 24 hours, you may be able to modify or cancel it without fees. Depending on the airline and the ticket type you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for further details.

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*Available to One Key members.