Popular airlines from Tri-Cities, TN (TRI-Tri-Cities Regional) to Chicago O'Hare Intl. Airport (ORD)
American AirlinesAmerican Airlines
DeltaDelta
- Plan, book, fly with confidence
- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 30% on select hotels after you book a flight*
Cheap Flights from Tri-Cities to Chicago (TRI-ORD)
Prices were available within the past 7 days and start at $105 for one-way flights and $209 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Frequently asked questions
Travel information
Travel information
Origin airport | Tri-Cities Regional |
Destination airport | O'Hare Intl. |
Airlines serving | American Airlines, Delta |
Roundtrip price | $208 |
Distance | 480 mi |
Book with confidence
Book with confidence
The cheapest times to fly from Tri-Cities to Chicago
On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Tri-Cities to Chicago are during the month of May. You can find some of the cheapest flights from Tri-Cities to Chicago with Expedia's search tool and vast selection of airlines.
The best time to book a flight from Tri-Cities to Chicago
Sunday is one of the best days to book for cheap flights from Tri-Cities to Chicago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.
How to find cheap round-trip tickets from Tri-Cities to Chicago
Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Tri-Cities to Chicago in 2025. You can also book with separate airlines for your outbound and return journeys, from $105 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.
Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Tri-Cities to Chicago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.
You could also save big by booking one of Expedia's vacation packages. Bundling together your Tri-Cities to Chicago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.
*Terms apply.
Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.
Be inspired and discover more with Expedia
Be inspired and discover more with Expedia
Flights
- Flights from Asheville Regional
- Flights from Pike County - Hatcher Field
- Flights from Tri-State
- Flights from Greenville-Spartanburg Intl.
- Flights from Smith Reynolds
- Flights from Raleigh County Memorial
- Flights from Virginia Highlands
- Flights from Concord Regional
- Flights from McGhee Tyson
- Flights from Charlotte-Douglas Intl.
- American Airlines Tri-Cities (TRI) to Tucson (TUS) flights
- American Airlines Tri-Cities (TRI) to New York (LGA) flights
- Delta Tri-Cities (TRI) to Fort Lauderdale (FLL) flights
- Delta Tri-Cities (TRI) to Portland (PDX) flights
- Delta Tri-Cities (TRI) to Los Angeles (LAX) flights
- American Airlines Tri-Cities (TRI) to Newark Liberty Intl. Airport (EWR) flights
- Spirit Airlines New York (LGA) to Chicago (ORD) flights
- JetBlue Airways Boston (BOS) to Chicago (ORD) flights
- JetBlue Airways New York (JFK) to Chicago (ORD) flights
- Spirit Airlines Charlotte (CLT) to Chicago (ORD) flights
- Alaska Airlines Phoenix (PHX) to Chicago (ORD) flights
- Spirit Airlines Tampa (TPA) to Chicago (ORD) flights
- Frontier Airlines Denver (DEN) to Chicago (ORD) flights
- Alaska Airlines Los Angeles (LAX) to Chicago (ORD) flights
- American Airlines Miami (MIA) to Chicago (ORD) flights
- JetBlue Airways Fort Lauderdale (FLL) to Chicago (ORD) flights
- Delta Tri-Cities (TRI) to Tampa (TPA) flights
- American Airlines Tri-Cities (TRI) to Denver (DEN) flights
- Delta Tri-Cities (TRI) to Ontario (ONT) flights
- Flights to San Diego
- Flights to Nashville
- Flights to San Francisco
- Flights to Las Vegas
- Flights to San Antonio
- Flights to Boston
- Flights to Pigeon Forge
- Flights to Key West
- Flights to Fort Lauderdale
- Flights to Miami
- Flights to Atlanta
- Flights to Chicago
- Flights to Gatlinburg
- Flights to Washington
- Flights to Houston
- Flights to Los Angeles
- Flights to Honolulu
- Flights to New Orleans
- Flights to Orlando
- Flights to New York
- Delta
- KLM
- WestJet
- Qatar Airways
- Aeromexico
- Air France
- American Airlines
- Virgin Atlantic
- Korean Air
- Scandinavian Airlines
- Flights from Chicago (ORD) to New York (LGA)
- Flights from Tri-Cities (TRI) to New York (LGA)
- Flights from Tri-Cities (TRI) to Jacksonville (JAX)
- Flights from Chicago (ORD) to Atlanta (ATL)
- Flights from Tri-Cities (TRI) to New York (JFK)
- Flights from Chicago (ORD) to Houston (HOU)
- Flights from Tri-Cities (TRI) to Miami (MIA)
- Flights from Chicago (ORD) to Miami (MIA)
- Flights from Chicago (ORD) to San Juan (SJU)
- Flights from Tri-Cities (TRI) to Fort Lauderdale (FLL)
- Flights from Chicago (ORD) to Orlando (MCO)
- Flights from Nashville (BNA) to Orlando (MCO)
- Flights from Chicago (ORD) to Phoenix (PHX)
- Flights from Tri-Cities (TRI) to Dallas (DAL)
- Flights from Tri-Cities (TRI) to Portland (PDX)
- Flights from Chicago (ORD) to Los Angeles (LAX)
- Flights from Tri-Cities (TRI) to Los Angeles (LAX)
- Flights from Nashville (BNA) to Las Vegas (LAS)
- Flights from Chicago (ORD) to Las Vegas (LAS)
- Flights from Chicago (ORD) to San Francisco (SFO)
- Flights from Tri-Cities (TRI) to Newark Liberty Intl. Airport (EWR)
- Flights from Chicago (ORD) to Honolulu (HNL)
- Flights from Phoenix (PHX) to Chicago (ORD)
- Flights from Seattle (SEA) to Chicago (ORD)
- Flights from Fort Lauderdale (FLL) to Chicago (ORD)
- Flights from Miami (MIA) to Chicago (ORD)
- Flights from Houston (HOU) to Chicago (ORD)
- Flights from Dallas (DFW) to Chicago (ORD)
- Flights from Denver (DEN) to Chicago (ORD)
- Flights from Atlanta (ATL) to Chicago (ORD)
- Flights from Boston (BOS) to Chicago (ORD)
- Flights from Tampa (TPA) to Chicago (ORD)
- Flights from Los Angeles (LAX) to Chicago (ORD)
- Flights from Newark Liberty Intl. Airport (EWR) to Chicago (ORD)
- Flights from Dallas (DAL) to Chicago (ORD)
- Flights from New York (LGA) to Chicago (ORD)
- Flights from Minneapolis (MSP) to Chicago (ORD)
- Flights from Orlando (MCO) to Chicago (ORD)
- Flights from Charlotte (CLT) to Chicago (ORD)
- Flights from New York (JFK) to Chicago (ORD)
- Flights from Philadelphia (PHL) to Chicago (ORD)
- Flights from Los Angeles (LAX) to Nashville (BNA)
- Flights from Philadelphia (PHL) to Nashville (BNA)
- Flights from Chicago (ORD) to Dallas (DFW)
- Flights from Chicago (ORD) to Mexico City (MEX)
- Flights from Tri-Cities (TRI) to Houston (IAH)
- Flights from Chicago (ORD) to Seattle (SEA)
- Flights from Chicago (ORD) to San Diego (SAN)
- Flights from Chicago (ORD) to Tampa (TPA)
- Flights from Tri-Cities (TRI) to Tampa (TPA)
- Flights from Chicago (ORD) to Denver (DEN)
- Flights from Tri-Cities (TRI) to Denver (DEN)