
Popular airlines from Tri-Cities, TN (TRI-Tri-Cities Regional) to Greenville-Spartanburg Intl. Airport (GSP)
- American Airlines
American Airlines
- United
United
- Southwest Airlines
Southwest Airlines
- Delta
Delta
- Frontier Airlines
Frontier Airlines
- JetBlue Airways
JetBlue Airways
- Alaska Airlines
Alaska Airlines
Cheap Flights from Tri-Cities to Greenville (TRI-GSP)
Prices were available within the past 7 days and start at $239 for one-way flights and $407 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.










Frequently asked questions
Travel information
Travel information
Origin airport | Tri-Cities Regional |
Destination airport | Greenville-Spartanburg Intl. |
Roundtrip price | $406 |
Distance | 110 mi |
Book with confidence
Book with confidence
The cheapest times to fly from Tri-Cities to Greenville
On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Tri-Cities to Greenville are during the month of May. You can find some of the cheapest flights from Tri-Cities to Greenville with Expedia's search tool and vast selection of airlines.
The best time to book a flight from Tri-Cities to Greenville
Sunday is one of the best days to book for cheap flights from Tri-Cities to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.
How to find cheap round-trip tickets from Tri-Cities to Greenville
Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Tri-Cities to Greenville in 2025. You can also book with separate airlines for your outbound and return journeys, from $239 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.
Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Tri-Cities to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.
You could also save big by booking one of Expedia's vacation packages. Bundling together your Tri-Cities to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.
*Terms apply.
Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.
Be inspired and discover more with Expedia
Be inspired and discover more with Expedia
Flights
- Flights from Nashville (BNA) to Denver (DEN)
- Flights from Tri-Cities (TRI) to Denver (DEN)
- Flights from Tri-Cities (TRI) to Fort Lauderdale (FLL)
- Flights from Tri-Cities (TRI) to Miami (MIA)
- Flights from Nashville (BNA) to New York (JFK)
- Flights from Tri-Cities (TRI) to New York (JFK)
- Flights from Tri-Cities (TRI) to New York (LGA)
- Flights from Tri-Cities (TRI) to Newark Liberty Intl. Airport (EWR)
- Flights from Nashville (BNA) to Seattle (SEA)
- Flights from Philadelphia (PHL) to Charleston (CHS)
- Flights from Tri-Cities (TRI) to Jacksonville (JAX)
- Flights from Tri-Cities (TRI) to Portland (PDX)
- Flights from Nashville (BNA) to Dallas (DFW)
- Flights from Memphis (MEM) to Dallas (DFW)
- Flights from Nashville (BNA) to Las Vegas (LAS)
- Flights from Memphis (MEM) to Las Vegas (LAS)
- Flights from Nashville (BNA) to Los Angeles (LAX)
- Flights from Tri-Cities (TRI) to Los Angeles (LAX)
- Flights from Philadelphia (PHL) to Myrtle Beach (MYR)
- Flights from Newark Liberty Intl. Airport (EWR) to Myrtle Beach (MYR)
- Flights from Boston (BOS) to Myrtle Beach (MYR)
- Flights from Raleigh (RDU) to Nashville (BNA)
- Flights from Denver (DEN) to Nashville (BNA)
- Flights from New York (LGA) to Nashville (BNA)
- Flights from Newark Liberty Intl. Airport (EWR) to Nashville (BNA)
- Flights from Chicago (ORD) to Nashville (BNA)
- Flights from Phoenix (PHX) to Nashville (BNA)
- Flights from Los Angeles (LAX) to Nashville (BNA)
- Flights from Philadelphia (PHL) to Nashville (BNA)
- Flights from Seattle (SEA) to Nashville (BNA)
- Flights from Orlando (MCO) to Nashville (BNA)
- Flights from Minneapolis (MSP) to Nashville (BNA)
- Flights from Tampa (TPA) to Nashville (BNA)
- Flights from Detroit (DTW) to Nashville (BNA)
- Flights from Boston (BOS) to Nashville (BNA)
- Flights from Dallas (DFW) to Nashville (BNA)
- Flights from Nashville (BNA) to Orlando (MCO)
- Flights from Memphis (MEM) to Orlando (MCO)
- Flights from Tri-Cities (TRI) to Dallas (DAL)
- Flights from Nashville (BNA) to Chicago (ORD)
- Flights from Tri-Cities (TRI) to Tampa (TPA)
- Flights from Tri-Cities (TRI) to Houston (IAH)
- Flights from Denver (DEN) to Greenville (GSP)
- Flights from Miami (MIA) to Greenville (GSP)
- Flights from Los Angeles (LAX) to Greenville (GSP)
- Flights from New York (LGA) to Greenville (GSP)
- Flights from Newark Liberty Intl. Airport (EWR) to Greenville (GSP)
- Flights from Portland (PDX) to Greenville (GSP)
- Flights from Boston (BOS) to Greenville (GSP)
- Flights from Chicago (ORD) to Greenville (GSP)
- Flights from Detroit (DTW) to Greenville (GSP)
- Flights from Minneapolis (MSP) to Greenville (GSP)
- Flights from Tampa (TPA) to Greenville (GSP)
- Flights from Washington (DCA) to Greenville (GSP)
- Flights from Tri-State
- Flights from Pike County - Hatcher Field
- Flights from McGhee Tyson
- Flights from Asheville Regional
- Flights from Raleigh County Memorial
- Flights from Smith Reynolds
- Flights from Charlotte-Douglas Intl.
- Flights from Virginia Highlands
- Flights from Concord Regional
- Flights from Greenville-Spartanburg Intl.
- Flights to New York
- Flights to San Diego
- Flights to Gatlinburg
- Flights to San Antonio
- Flights to Nashville
- Flights to San Francisco
- Flights to Orlando
- Flights to Atlanta
- Flights to Pigeon Forge
- Flights to Key West
- Flights to Chicago
- Flights to Las Vegas
- Flights to Washington
- Flights to Boston
- Flights to Houston
- Flights to Los Angeles
- Flights to Honolulu
- Flights to New Orleans
- Flights to Fort Lauderdale
- Flights to Miami
- American Airlines Tri-Cities (TRI) to Denver (DEN) flights
- Delta Tri-Cities (TRI) to Ontario (ONT) flights
- Delta Tri-Cities (TRI) to Fort Lauderdale (FLL) flights
- American Airlines Tri-Cities (TRI) to Tucson (TUS) flights
- American Airlines Tri-Cities (TRI) to New York (LGA) flights
- American Airlines Tri-Cities (TRI) to Newark Liberty Intl. Airport (EWR) flights
- Delta Tri-Cities (TRI) to Portland (PDX) flights
- Delta Tri-Cities (TRI) to Los Angeles (LAX) flights
- Delta Tri-Cities (TRI) to Tampa (TPA) flights
- Delta Los Angeles (LAX) to Greenville (GSP) flights
- United Newark Liberty Intl. Airport (EWR) to Greenville (GSP) flights
- Delta New York (LGA) to Greenville (GSP) flights
- Delta Tampa (TPA) to Greenville (GSP) flights
- Delta Denver (DEN) to Greenville (GSP) flights
- United Chicago (ORD) to Greenville (GSP) flights
- American Airlines Washington (DCA) to Greenville (GSP) flights
- American Airlines Miami (MIA) to Greenville (GSP) flights
- United Portland (PDX) to Greenville (GSP) flights
- Delta Minneapolis (MSP) to Greenville (GSP) flights
- Virgin Atlantic
- Korean Air
- Scandinavian Airlines
- Delta
- KLM
- WestJet
- Qatar Airways
- Aeromexico
- Air France
- American Airlines