Cheap Flights from Syracuse (SYR) to St. Louis (CPS)

Popular airlines from Hancock Intl. Airport (SYR) to St. Louis, MO (CPS-St. Louis Downtown)

Find available prices by choosing your travel dates.
Flights from Syracuse (SYR) to St. Louis (CPS)
Origin airport
Hancock Intl.
Destination airport
St. Louis Downtown
Distance
796 mi

Syracuse to St. Louis Flights

The cheapest times to fly from Syracuse to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Syracuse to St. Louis are during the month of . You can find some of the cheapest flights from Syracuse to St. Louis with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Syracuse to St. Louis

Sunday is one of the best days to book for cheap flights from Syracuse to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Syracuse to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Syracuse to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Syracuse to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Syracuse to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Hancock Intl. Airport (SYR) to St. Louis Downtown Airport (CPS) cost?
Discover the latest flight deals from SYR to CPS by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from SYR to CPS?
The cheapest flights from SYR to CPS are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from SYR to CPS?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from SYR to CPS. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Hancock Intl. Airport (SYR) to St. Louis Downtown Airport (CPS)?
Direct flights from Hancock Intl. Airport (SYR) to St. Louis Downtown Airport (CPS) aren’t available daily, so you’ll need to take a flight with a layover. Explore your options with Expedia’s filters. Enter your travel details and choose either “1 Stop” or “2+ Stops.”
What day of the week has the most flights from SYR to CPS?
Typically you’ll find the largest variety of flight choices on a Friday. Tuesdays are often the quietest.* But this can change depending on the airline, season and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Hancock Intl. Airport (SYR) to St. Louis Downtown Airport (CPS)?
To reach St. Louis Downtown Airport (CPS) without delays, select a flight that takes off from Hancock Intl. Airport (SYR) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Hancock Intl. Airport (SYR) to St. Louis Downtown Airport (CPS) last-minute?
Last-minute fares from SYR to CPS are usually more expensive. To lock in the cheapest rates, start searching for flights as early as possible. That said, if your travel plans are flexible, you may score a cheap ticket right before your trip.
Is it cheaper to book a SYR to CPS flight and hotel package?
You’ll generally save money by securing a SYR to CPS flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it’s simple to manage it all in one convenient place. After choosing your ideal accommodations and flights, consider other add-ons like tours, car rentals and activities.
Can I cancel or change the date of my flight from Hancock Intl. Airport (SYR) to St. Louis Downtown Airport (CPS)?
In most instances, you can cancel or modify your SYR to CPS flight. However, additional charges may apply, especially if you made your booking over 24 hours ago. Double-check your itinerary for the airline’s fees and rules on flight changes, or if you’d like further information, visit our Customer Service portal.

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*Available to One Key members.