$104 Cheap Flights from St. Louis (STL) to San Francisco (SFO)

View $104 flight on Wed, Apr 30, 2025Opens in a new window

Popular airlines from St. Louis Lambert Intl. Airport (STL) to San Francisco Intl. Airport (SFO)

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Find available prices by choosing your travel dates.

Cheap Flights from St. Louis to San Francisco (STL-SFO)

Prices were available within the past 7 days and start at $104 for one-way flights and $198 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Sat, May 24 - Thu, May 29
STL
St. Louis
SFO
San Francisco
$198 Roundtrip, found 1 day ago
$198
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sat, May 24 from St. Louis to San Francisco, returning Thu, May 29, priced at $198 found 1 day ago
Frontier Airlines
Mon, Apr 28 - Fri, May 2
STL
St. Louis
SFO
San Francisco
$208 Roundtrip, found 4 hours ago
$208
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Mon, Apr 28 from St. Louis to San Francisco, returning Fri, May 2, priced at $208 found 4 hours ago
Frontier Airlines
Thu, May 8 - Sun, May 11
STL
St. Louis
SFO
San Francisco
$228 Roundtrip, just found
$228
Roundtrip
just found
Select Frontier Airlines flight, departing Thu, May 8 from St. Louis to San Francisco, returning Sun, May 11, priced at $228 just found
Frontier Airlines
Sat, Apr 26 - Sun, May 4
STL
St. Louis
SFO
San Francisco
$238 Roundtrip, found 3 hours ago
$238
Roundtrip
found 3 hours ago
Select Frontier Airlines flight, departing Sat, Apr 26 from St. Louis to San Francisco, returning Sun, May 4, priced at $238 found 3 hours ago
Frontier Airlines
Mon, Jun 2 - Fri, Jun 6
STL
St. Louis
SFO
San Francisco
$248 Roundtrip, found 1 hour ago
$248
Roundtrip
found 1 hour ago
Select Frontier Airlines flight, departing Mon, Jun 2 from St. Louis to San Francisco, returning Fri, Jun 6, priced at $248 found 1 hour ago
Frontier Airlines
Fri, May 23 - Wed, May 28
STL
St. Louis
SFO
San Francisco
$250 Roundtrip, found 1 day ago
$250
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Fri, May 23 from St. Louis to San Francisco, returning Wed, May 28, priced at $250 found 1 day ago
American Airlines
Wed, Aug 6 - Wed, Aug 20
STL
St. Louis
SFO
San Francisco
$277 Roundtrip, found 2 days ago
$277
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Aug 6 from St. Louis to San Francisco, returning Wed, Aug 20, priced at $277 found 2 days ago
Delta
Fri, Jun 6 - Mon, Jun 9
STL
St. Louis
SFO
San Francisco
$283 Roundtrip, found 6 days ago
$283
Roundtrip
found 6 days ago
Select Delta flight, departing Fri, Jun 6 from St. Louis to San Francisco, returning Mon, Jun 9, priced at $283 found 6 days ago
Alaska Airlines
Wed, May 7 - Tue, May 13
STL
St. Louis
SFO
San Francisco
$306 Roundtrip, found 1 day ago
$306
Roundtrip
found 1 day ago
Select Alaska Airlines flight, departing Wed, May 7 from St. Louis to San Francisco, returning Tue, May 13, priced at $306 found 1 day ago
United
Wed, May 28 - Tue, Jun 3
STL
St. Louis
SFO
San Francisco
$323 Roundtrip, found 7 hours ago
$323
Roundtrip
found 7 hours ago
Select United flight, departing Wed, May 28 from St. Louis to San Francisco, returning Tue, Jun 3, priced at $323 found 7 hours ago
Flights from St. Louis (STL) to San Francisco (SFO)
Origin airport
Lambert-St. Louis Intl.
Destination airport
San Francisco Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Roundtrip price
$198
Distance
1731 mi

St. Louis to San Francisco Flights

The cheapest times to fly from St. Louis to San Francisco

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from St. Louis to San Francisco are during the month of May. You can find some of the cheapest flights from St. Louis to San Francisco with Expedia's search tool and vast selection of airlines.

The best time to book a flight from St. Louis to San Francisco

Sunday is one of the best days to book for cheap flights from St. Louis to San Francisco: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from St. Louis to San Francisco

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from St. Louis to San Francisco in 2025. You can also book with separate airlines for your outbound and return journeys, from $104 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap St. Louis to San Francisco flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your St. Louis to San Francisco airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Lambert-St. Louis Intl. Airport (STL) to San Francisco Intl. Airport (SFO) cost?
Snag cheap return flights starting from $308 from Lambert-St. Louis Intl. Airport (STL) to San Francisco Intl. Airport (SFO). This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a United flight leaving STL on May 2 2025 and touching down at SFO. The price was last updated on April 23 2025 and has not changed since.
What is the cheapest month to fly from STL to SFO?
The cheapest flights from STL to SFO are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Lambert-St. Louis Intl. Airport (STL) to San Francisco Intl. Airport (SFO)?
Take a direct flight with United Airlines and journey straight from Lambert-St. Louis Intl. Airport (STL) to San Francisco Intl. Airport (SFO).
What is the cheapest airline that flies from STL to SFO?
With prices as low as $160 for a one-way flight from STL to SFO, United is currently the cheapest airline flying this route. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from STL on May 28 2025. Prices were last updated on April 23 2025 and have not changed since.
How many flights per day from Lambert-St. Louis Intl. Airport (STL) to San Francisco Intl. Airport (SFO)?
On average, only 1 direct flight departs daily from Lambert-St. Louis Intl. Airport (STL) to San Francisco Intl. Airport (SFO). Need other options? Use Expedia’s filter tool to discover flights with layovers and explore a new city along the way.
What are the most popular departure times for flights from Lambert-St. Louis Intl. Airport (STL) to San Francisco Intl. Airport (SFO)?
Flights between STL and SFO are their busiest at 7 AM. If you’d like a more relaxed atmosphere and possibly cheaper fares, look for a departure that’s outside typical rush times.
What day of the week has the most flights from STL to SFO?
Friday offers the most flights from Lambert-St. Louis Intl. Airport (STL) to San Francisco Intl. Airport (SFO). Consider jetting off on this day and you’ll have a greater chance of finding a departure that fits your itinerary.
What is the earliest flight from Lambert-St. Louis Intl. Airport (STL) to San Francisco Intl. Airport (SFO)?
Lambert-St. Louis Intl. Airport (STL)’s earliest flight to San Francisco Intl. Airport (SFO) takes off at approximately 7:00AM UTC-6. With a flight time of 4h 45m, you’ll arrive at around 9:45AM UTC-8.
How long does it take to fly from Lambert-St. Louis Intl. Airport (STL) to San Francisco Intl. Airport (SFO)?
It takes approximately 4 hours and 39 minutes to cover the 1,750 mi from STL to SFO.
What is the best time to fly from Lambert-St. Louis Intl. Airport (STL) to San Francisco Intl. Airport (SFO)?
Book a flight from Lambert-St. Louis Intl. Airport (STL) to San Francisco Intl. Airport (SFO) that leaves before 3 PM to reduce the risk of cancellations. Later departures have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
What airports do you fly into for San Francisco from Lambert-St. Louis Intl. Airport (STL)?
If you’re on a direct flight from Lambert-St. Louis Intl. Airport (STL) to San Francisco, San Francisco Intl. Airport (SFO) is the only airport you can land at.
Is it cheaper to buy a plane ticket from Lambert-St. Louis Intl. Airport (STL) to San Francisco Intl. Airport (SFO) last-minute?
Booking your flight from STL to SFO right before your journey is typically more expensive. However, if you’re flexible with your departure times and dates, you could score a cheap last-minute fare.
Is it cheaper to book a STL to SFO flight and hotel package?
Compared with arranging hotels and flights separately, booking a STL to SFO flight and hotel package with Expedia could result in significant savings. Better still, having it all in one place will take the stress out of planning your trip. Simply pick your flights and select from our wide range of stays, then customize your trip with extras like activities, tours and car rentals.
Can I cancel or change the date of my flight from Lambert-St. Louis Intl. Airport (STL) to San Francisco Intl. Airport (SFO)?
If you reserved your STL to SFO flight in the last 24 hours, you may be able to modify or cancel it at no cost. Depending on the airline and the type of fare you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal for more details.

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*Available to One Key members.