$100 Cheap Flights from St. Louis (STL) to Key West (EYW)

View $100 flight on Tue, Jul 1, 2025Opens in a new window

Popular airlines from St. Louis Lambert Intl. Airport (STL) to Key West Intl. Airport (EYW)

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Find available prices by choosing your travel dates.

Cheap Flights from St. Louis to Key West (STL-EYW)

Prices were available within the past 7 days and start at $100 for one-way flights and $204 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sun, May 25 - Thu, May 29
STL
St. Louis
EYW
Key West
$204 Roundtrip, found 5 hours ago
$204
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Sun, May 25 from St. Louis to Key West, returning Thu, May 29, priced at $204 found 5 hours ago
Delta
Sun, May 25 - Thu, May 29
STL
St. Louis
EYW
Key West
$211 Roundtrip, found 5 hours ago
$211
Roundtrip
found 5 hours ago
Select Delta flight, departing Sun, May 25 from St. Louis to Key West, returning Thu, May 29, priced at $211 found 5 hours ago
American Airlines
Sun, May 25 - Thu, May 29
STL
St. Louis
EYW
Key West
$216 Roundtrip, found 5 hours ago
$216
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Sun, May 25 from St. Louis to Key West, returning Thu, May 29, priced at $216 found 5 hours ago
Delta
Sun, May 25 - Thu, May 29
STL
St. Louis
EYW
Key West
$217 Roundtrip, found 5 hours ago
$217
Roundtrip
found 5 hours ago
Select Delta flight, departing Sun, May 25 from St. Louis to Key West, returning Thu, May 29, priced at $217 found 5 hours ago
American Airlines
Wed, May 21 - Thu, May 29
STL
St. Louis
EYW
Key West
$225 Roundtrip, found 1 day ago
$225
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, May 21 from St. Louis to Key West, returning Thu, May 29, priced at $225 found 1 day ago
American Airlines
Tue, Jul 1 - Tue, Jul 8
STL
St. Louis
EYW
Key West
$228 Roundtrip, just found
$228
Roundtrip
just found
Select American Airlines flight, departing Tue, Jul 1 from St. Louis to Key West, returning Tue, Jul 8, priced at $228 just found
American Airlines
Thu, May 29 - Tue, Jun 3
STL
St. Louis
EYW
Key West
$230 Roundtrip, found 1 hour ago
$230
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Thu, May 29 from St. Louis to Key West, returning Tue, Jun 3, priced at $230 found 1 hour ago
American Airlines
Fri, May 30 - Tue, Jun 3
STL
St. Louis
EYW
Key West
$232 Roundtrip, found 4 hours ago
$232
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Fri, May 30 from St. Louis to Key West, returning Tue, Jun 3, priced at $232 found 4 hours ago
American Airlines
Thu, May 29 - Tue, Jun 3
STL
St. Louis
EYW
Key West
$233 Roundtrip, found 1 hour ago
$233
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Thu, May 29 from St. Louis to Key West, returning Tue, Jun 3, priced at $233 found 1 hour ago
United
Sat, Apr 26 - Tue, Apr 29
STL
St. Louis
EYW
Key West
$379 Roundtrip, found 2 days ago
$379
Roundtrip
found 2 days ago
Select United flight, departing Sat, Apr 26 from St. Louis to Key West, returning Tue, Apr 29, priced at $379 found 2 days ago

Frequently asked questions

How much does a flight from Lambert-St. Louis Intl. Airport (STL) to Key West Intl. Airport (EYW) cost?
Discover the latest flight deals from STL to EYW by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from STL to EYW?
The cheapest flights from STL to EYW are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from STL to EYW?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from STL to EYW. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Lambert-St. Louis Intl. Airport (STL) to Key West Intl. Airport (EYW)?
Direct flights from Lambert-St. Louis Intl. Airport (STL) to Key West Intl. Airport (EYW) aren’t available daily, so you’ll need to take a flight with a layover. Explore your options with Expedia’s filters. Enter your travel dates and select either “1 Stop” or “2+ Stops.”
What day of the week has the most flights from STL to EYW?
Friday is typically the busiest day for flights, while Tuesday tends to be the quietest.* Keep in mind that flight schedules can change based on various factors, including the time of year and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Lambert-St. Louis Intl. Airport (STL) to Key West Intl. Airport (EYW)?
To land at Key West Intl. Airport (EYW) without delays, select a flight that takes off from Lambert-St. Louis Intl. Airport (STL) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Lambert-St. Louis Intl. Airport (STL) to Key West Intl. Airport (EYW) last-minute?
Waiting until just before your trip to book a ticket from STL to EYW generally means paying more. While you may find some last-minute deals, they aren’t always guaranteed. Allow some flexibility in your schedule to maximize your chances of scoring a bargain.
Is it cheaper to book a STL to EYW flight and hotel package?
Compared with arranging flights and hotels separately, booking a STL to EYW flight and hotel package with Expedia could result in significant savings. Better still, having everything in one convenient place takes the hassle out of travel planning. Just pick your flights and choose from our extensive range of stays, then personalize your trip with other add-ons like tours, car rentals and activities.
Can I cancel or change the date of my flight from Lambert-St. Louis Intl. Airport (STL) to Key West Intl. Airport (EYW)?
It’s generally possible to cancel or reschedule your STL to EYW flight. However, if it’s been more than 24 hours since booking, additional fees may apply. Check your airline’s policies in your itinerary to see what changes are allowed and if any costs are involved. You’ll also find more details on our Customer Service portal.
*Available to One Key members.