$595 Cheap Flights from Santiago (STI) to Madrid (MAD)

View $595 flight on Sat, Dec 20, 2025Opens in a new window

Popular airlines from Cibao Intl. Airport (STI) to Adolfo Suarez Madrid-Barajas Airport (MAD)

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Find available prices by choosing your travel dates.

Cheap Flights from Santiago to Madrid (STI-MAD)

Prices were available within the past 7 days and start at $595 for one-way flights and $851 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Air Europa
Sat, Oct 25 - Sat, Nov 8
STI
Santiago de los Caballeros
MAD
Madrid
$851 Roundtrip, found 1 day ago
$851
Roundtrip
found 1 day ago
Select Air Europa flight, departing Sat, Oct 25 from Santiago de los Caballeros to Madrid, returning Sat, Nov 8, priced at $851 found 1 day ago
Air Europa
Sat, May 24 - Sat, May 31
STI
Santiago de los Caballeros
MAD
Madrid
$887 Roundtrip, found 21 hours ago
$887
Roundtrip
found 21 hours ago
Select Air Europa flight, departing Sat, May 24 from Santiago de los Caballeros to Madrid, returning Sat, May 31, priced at $887 found 21 hours ago
Air Europa
Sat, May 10 - Sat, May 31
STI
Santiago de los Caballeros
MAD
Madrid
$935 Roundtrip, found 7 hours ago
$935
Roundtrip
found 7 hours ago
Select Air Europa flight, departing Sat, May 10 from Santiago de los Caballeros to Madrid, returning Sat, May 31, priced at $935 found 7 hours ago
JetBlue Airways
Sun, Oct 12 - Tue, Oct 21
STI
Santiago de los Caballeros
MAD
Madrid
$940 Roundtrip, found 23 hours ago
$940
Roundtrip
found 23 hours ago
Select JetBlue Airways flight, departing Sun, Oct 12 from Santiago de los Caballeros to Madrid, returning Tue, Oct 21, priced at $940 found 23 hours ago
JetBlue Airways
Wed, Oct 15 - Tue, Oct 21
STI
Santiago de los Caballeros
MAD
Madrid
$958 Roundtrip, found 23 hours ago
$958
Roundtrip
found 23 hours ago
Select JetBlue Airways flight, departing Wed, Oct 15 from Santiago de los Caballeros to Madrid, returning Tue, Oct 21, priced at $958 found 23 hours ago
Air Europa
Sat, Oct 11 - Sat, Oct 18
STI
Santiago de los Caballeros
MAD
Madrid
$965 Roundtrip, found 23 hours ago
$965
Roundtrip
found 23 hours ago
Select Air Europa flight, departing Sat, Oct 11 from Santiago de los Caballeros to Madrid, returning Sat, Oct 18, priced at $965 found 23 hours ago
Air Europa
Sat, May 10 - Sat, May 17
STI
Santiago de los Caballeros
MAD
Madrid
$971 Roundtrip, found 15 hours ago
$971
Roundtrip
found 15 hours ago
Select Air Europa flight, departing Sat, May 10 from Santiago de los Caballeros to Madrid, returning Sat, May 17, priced at $971 found 15 hours ago
United
Tue, Sep 23 - Wed, Oct 8
STI
Santiago de los Caballeros
MAD
Madrid
$1,150 Roundtrip, found 3 days ago
$1,150
Roundtrip
found 3 days ago
Select United flight, departing Tue, Sep 23 from Santiago de los Caballeros to Madrid, returning Wed, Oct 8, priced at $1,150 found 3 days ago
American Airlines
Tue, Nov 25 - Wed, Dec 10
STI
Santiago de los Caballeros
MAD
Madrid
$1,304 Roundtrip, found 1 day ago
$1,304
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Nov 25 from Santiago de los Caballeros to Madrid, returning Wed, Dec 10, priced at $1,304 found 1 day ago
Delta
Tue, Oct 14 - Sun, Oct 19
STI
Santiago de los Caballeros
MAD
Madrid
$2,026 Roundtrip, found 23 hours ago
$2,026
Roundtrip
found 23 hours ago
Select Delta flight, departing Tue, Oct 14 from Santiago de los Caballeros to Madrid, returning Sun, Oct 19, priced at $2,026 found 23 hours ago
Flights from Santiago (STI) to Madrid (MAD)
Origin airport
Cibao Intl.
Destination airport
Adolfo Suárez Madrid-Barajas
Airlines serving
Air Europa, American Airlines, Delta, JetBlue Airways, United
Roundtrip price
$851
Distance
4165 mi

Santiago to Madrid Flights

The cheapest times to fly from Santiago to Madrid

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santiago to Madrid are during the month of October. You can find some of the cheapest flights from Santiago to Madrid with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Santiago to Madrid

Sunday is one of the best days to book for cheap flights from Santiago to Madrid: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Santiago to Madrid

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santiago to Madrid in 2025. You can also book with separate airlines for your outbound and return journeys, from $595 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santiago to Madrid flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santiago to Madrid airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Cibao Intl. Airport (STI) to Adolfo Suarez Madrid-Barajas Airport (MAD) cost?
Score cheap return fares from Cibao Intl. Airport (STI) to Adolfo Suarez Madrid-Barajas Airport (MAD) starting from $1007. Grab a seat and set off on your next adventure. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Air Europa flight leaving STI on May 17 2025 and touching down at MAD. The price was last updated on April 23 2025 and has not changed since.
What is the cheapest month to fly from STI to MAD?
The cheapest flights from STI to MAD are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Cibao Intl. Airport (STI) to Adolfo Suarez Madrid-Barajas Airport (MAD)?
You can travel nonstop from Cibao Intl. Airport (STI) to Adolfo Suarez Madrid-Barajas Airport (MAD) on an Air Europa flight.
What is the cheapest airline that flies from STI to MAD?
Currently, the cheapest airline offering one-way flights from STI to MAD is Air Europa. You can take off on this route from $595. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from STI on July 5 2025. Prices were last updated on April 23 2025 and have not changed since.
How many flights per day from Cibao Intl. Airport (STI) to Adolfo Suarez Madrid-Barajas Airport (MAD)?
On average you can take your pick of 1 direct weekly flights from Cibao Intl. Airport (STI) to Adolfo Suarez Madrid-Barajas Airport (MAD). For more options, consider a flight with a layover. Just enter your dates on Expedia and then filter your search to show one stop or more.
What are the most popular departure times for flights from Cibao Intl. Airport (STI) to Adolfo Suarez Madrid-Barajas Airport (MAD)?
Flights between STI and MAD are their busiest at 10 PM. For a quieter experience and potentially cheaper tickets, look for a time outside the usual busy windows.
What day of the week has the most flights from STI to MAD?
Fly on a Saturday if you’re searching for the best choice of flights from Cibao Intl. Airport (STI) to Adolfo Suarez Madrid-Barajas Airport (MAD).
What is the earliest flight from Cibao Intl. Airport (STI) to Adolfo Suarez Madrid-Barajas Airport (MAD)?
Catch the earliest flight at around 10:35PM UTC-4, leaving from Cibao Intl. Airport (STI). You’ll be flying for approximately 8h 15m, touching down at Adolfo Suarez Madrid-Barajas Airport (MAD) at approximately 11:50AM UTC+1.
How long does it take to fly from Cibao Intl. Airport (STI) to Adolfo Suarez Madrid-Barajas Airport (MAD)?
The average flight time from STI to MAD is 8 hours and 15 minutes, covering a distance of 4,200 mi.
What airline has the least delays from STI to MAD?
With 94% of journeys generally landing on time, Air Europa has the best on-time performance for nonstop flights from Cibao Intl. Airport (STI) to Adolfo Suarez Madrid-Barajas Airport (MAD). To monitor your flight status and receive notifications if anything changes, simply head to the Expedia App.
What is the best time to fly from Cibao Intl. Airport (STI) to Adolfo Suarez Madrid-Barajas Airport (MAD)?
To avoid potential delays on the Cibao Intl. Airport (STI) to Adolfo Suarez Madrid-Barajas Airport (MAD) route, fly before 3 PM. Departures after this time are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
What airports do you fly into for Madrid from Cibao Intl. Airport (STI)?
If you’re traveling on a direct flight from Cibao Intl. Airport (STI) to Madrid, Adolfo Suarez Madrid-Barajas Airport (MAD) is the only airport you can touch down at.
Is it cheaper to buy a plane ticket from Cibao Intl. Airport (STI) to Adolfo Suarez Madrid-Barajas Airport (MAD) last-minute?
Booking your flight from STI to MAD right before your trip is typically more expensive. However, if there’s some wiggle room with your schedule, you could grab a cheap last-minute fare.
Is it cheaper to book a STI to MAD flight and hotel package?
Compared with arranging hotels and flights separately, booking a STI to MAD flight and hotel package with Expedia could result in significant savings. Better yet, having it all in one place will take the hassle out of planning your trip. Simply pick your flights and select from our extensive range of hotels, then tailor your trip with other add-ons like activities and car rentals.
Can I cancel or change the date of my flight from Cibao Intl. Airport (STI) to Adolfo Suarez Madrid-Barajas Airport (MAD)?
Typically, you can reschedule or cancel your STI to MAD flight. However, additional fees may apply, especially if you made your booking over 24 hours ago. Check your itinerary for the airline’s fees and policies on flight changes, or if you need further information, visit our Customer Service portal.

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*Available to One Key members.