$115 Cheap Flights from Orange County (SNA) to Knoxville (TYS)

Popular airlines from John Wayne Airport (SNA) to McGhee Tyson Airport (TYS)

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Find available prices by choosing your travel dates.

Cheap Flights from Orange County to Knoxville (SNA-TYS)

Prices were available within the past 7 days and start at $115 for one-way flights and $229 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
United
United
American Airlines
United
United
United
Delta
Alaska Airlines
Frontier Airlines
Flights from Orange County (SNA) to Knoxville (TYS)
Origin airport
John Wayne
Destination airport
McGhee Tyson
Airlines serving
Alaska Airlines, American Airlines, Delta, Frontier Airlines, United
Roundtrip price
$228
Distance
1919 mi

Orange County to Knoxville Flights

The cheapest times to fly from Orange County to Knoxville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Orange County to Knoxville are during the month of May. You can find some of the cheapest flights from Orange County to Knoxville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Orange County to Knoxville

Sunday is one of the best days to book for cheap flights from Orange County to Knoxville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Orange County to Knoxville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Orange County to Knoxville in 2025. You can also book with separate airlines for your outbound and return journeys, from $115 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Orange County to Knoxville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Orange County to Knoxville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

Is it cheaper to buy a plane ticket from John Wayne Airport to TYS last minute?
When it comes to booking your flights, being organized pays off. While it’s possible to pick up a deal on a John Wayne Airport (SNA) to TYS flight at the last minute, fares usually don’t get cheaper as the departure date nears. Based on flight pricing and demand studies in 2022, we have found that the sweet spot to book a domestic flight is between 28 – 35 days in advance. For international trips it’s three to four months.
What airports do you fly into for Knoxville from Santa Ana?
McGhee Tyson Airport (TYS), Gatlinburg, TN (GKT-Gatlinburg - Pigeon Forge) and Morristown, TN (MOR-Moore-Murrell) are your options when jetting from Santa Ana to Knoxville. Roughly 12 mi south of the heart of Knoxville, McGhee Tyson Airport (TYS) is the city’s major gateway. Consider things like flight schedules and the distance to your hotel before deciding where you fly into. Ijams Nature Center and Women’s Basketball Hall of Fame are two awesome attractions to check out when you reach your destination.
Can I change the date of my flight from John Wayne Airport to McGhee Tyson Airport (TYS)?
It’s a breeze to make changes to your John Wayne Airport to Knoxville Airport journey yourself. Just go to the Expedia Trips portal and hit “change flight.” Browse around for new flights and choose the one that better fits your plans. You’ll see an estimate of applicable flight change fees. You can also visit our Customer Service portal to chat to our Virtual Agent and quickly get answers to your questions.

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