Featured airlines
- Plan, book, fly with confidence
- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 30% on select hotels after you book a flight*
Cheap Flights from Santo Domingo to Mexico City (SDQ-MEX)
Prices were available within the past 7 days and start at $122 for one-way flights and $266 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Origin airport | Las Americas Intl. |
Destination airport | Felipe Ángeles Intl. |
Airlines serving | Aeromexico, American Airlines, Copa, Delta, Iberia, United, avianca |
Roundtrip price | $266 |
Distance | 1916 mi |
Santo Domingo to Mexico City Flights
The cheapest times to fly from Santo Domingo to Mexico City
On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santo Domingo to Mexico City are during the month of November. You can find some of the cheapest flights from Santo Domingo to Mexico City with Expedia's search tool and vast selection of airlines.
The best time to book a flight from Santo Domingo to Mexico City
Sunday is one of the best days to book for cheap flights from Santo Domingo to Mexico City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.
How to find cheap round-trip tickets from Santo Domingo to Mexico City
Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santo Domingo to Mexico City in 2025. You can also book with separate airlines for your outbound and return journeys, from $122 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.
Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santo Domingo to Mexico City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.
You could also save big by booking one of Expedia's vacation packages. Bundling together your Santo Domingo to Mexico City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.
*Terms apply.
Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.
Frequently asked questions
Explore a world of travel with Expedia
Flights
- JetBlue Airways Santo Domingo (SDQ) to Boston (BOS) flights
- American Airlines Santo Domingo (SDQ) to Philadelphia (PHL) flights
- Aeromexico Seattle (SEA) to Mexico City (MEX) flights
- Aeromexico Los Angeles (LAX) to Mexico City (MEX) flights
- Aeromexico Tijuana (TIJ) to Mexico City (MEX) flights
- Aeromexico Denver (DEN) to Mexico City (MEX) flights
- Aeromexico New York (JFK) to Mexico City (MEX) flights
- Aeromexico Miami (MIA) to Mexico City (MEX) flights
- JetBlue Airways Santo Domingo (SDQ) to Newark Liberty Intl. Airport (EWR) flights
- Air Europa Santo Domingo (SDQ) to Madrid (MAD) flights
- JetBlue Airways Santo Domingo (SDQ) to Fort Lauderdale (FLL) flights
- JetBlue Airways Santo Domingo (SDQ) to New York (JFK) flights
- Spirit Airlines
- avianca
- Delta
- KLM
- Iberia
- Copa
- Aeromexico
- JetBlue Airways
- Air France
- Arajet
- American Airlines
- Air Europa
- British Airways
- United
- Sky High Dominicana
- Frontier Airlines
- Flights from Gregorio Luperon Intl.
- Flights from Cibao Intl.
- Flights from Punta Cana Intl.
- Flights from La Isabela Intl.
- Flights from La Romana Intl.
- Flights from El Catey Intl.
- Flights from Santo Domingo (SDQ) to Chicago (ORD)
- Flights from New York (JFK) to Kingston (KIN)
- Flights from Santo Domingo (SDQ) to Washington (IAD)
- Flights from Santo Domingo (SDQ) to Washington (DCA)
- Flights from Santo Domingo (SDQ) to New York (LGA)
- Flights from Santo Domingo (SDQ) to Tampa (TPA)
- Flights from Santo Domingo (SDQ) to Boston (BOS)
- Flights from Hartford (BDL) to San Juan (SJU)
- Flights from New York (JFK) to San Juan (SJU)
- Flights from Chicago (ORD) to San Juan (SJU)
- Flights from Dallas (DFW) to San Juan (SJU)
- Flights from Baltimore (BWI) to San Juan (SJU)
- Flights from Detroit (DTW) to San Juan (SJU)
- Flights from Los Angeles (LAX) to San Juan (SJU)
- Flights from Raleigh (RDU) to San Juan (SJU)
- Flights from Minneapolis (MSP) to San Juan (SJU)
- Flights from Newark Liberty Intl. Airport (EWR) to San Juan (SJU)
- Flights from Philadelphia (PHL) to San Juan (SJU)
- Flights from Atlanta (ATL) to San Juan (SJU)
- Flights from New York (NYC) to San Juan (SJU)
- Flights from Orlando (MCO) to San Juan (SJU)
- Flights from Boston (BOS) to San Juan (SJU)
- Flights from Houston (IAH) to San Juan (SJU)
- Flights from Fort Lauderdale (FLL) to San Juan (SJU)
- Flights from Charlotte (CLT) to San Juan (SJU)
- Flights from Miami (MIA) to San Juan (SJU)
- Flights from Tampa (TPA) to San Juan (SJU)
- Flights from Washington (DCA) to San Juan (SJU)
- Flights from Miami (MIA) to Mexico City (MEX)
- Flights from Chicago (MDW) to Mexico City (MEX)
- Flights from New York (LGA) to Mexico City (MEX)
- Flights from Chicago (ORD) to Mexico City (MEX)
- Flights from San Antonio (SAT) to Mexico City (MEX)
- Flights from New York (JFK) to Mexico City (MEX)
- Flights from Dallas (DAL) to Mexico City (MEX)
- Flights from Los Angeles (LAX) to Mexico City (MEX)
- Flights from Charlotte (CLT) to Mexico City (MEX)
- Flights from Portland (PDX) to Mexico City (MEX)
- Flights from Denver (DEN) to Mexico City (MEX)
- Flights from Newark Liberty Intl. Airport (EWR) to Mexico City (MEX)
- Flights from San Juan (SJU) to St. Thomas (STT)
- Flights from San Juan (SJU) to Orlando (MCO)
- Flights from Santo Domingo (SDQ) to Newark Liberty Intl. Airport (EWR)
- Flights from Santo Domingo (SDQ) to Miami (MIA)
- Flights from Kingston (KIN) to Toronto (YYZ)
- Flights from Santo Domingo (SDQ) to Madrid (MAD)
- Flights from Santo Domingo (SDQ) to Medellín (MDE)
- Flights from Kingston (KIN) to Panama City (PTY)
- Flights from Santo Domingo (SDQ) to Fort Lauderdale (FLL)
- Flights from Kingston (KIN) to Fort Lauderdale (FLL)
- Flights from Houston (IAH) to Monterrey (MTY)
- Flights from New York (JFK) to Santo Domingo (SDQ)
- Flights from Kingston (KIN) to New York (JFK)
- Flights from Santo Domingo (SDQ) to New York (JFK)
- Flights to Cabo San Lucas
- Flights to Isla Mujeres
- Flights to Tijuana
- Flights to Mexico City
- Flights to Cozumel
- Flights to Guadalajara
- Flights to San José del Cabo
- Flights to Mazatlán
- Flights to Santa María Huatulco
- Flights to Playa del Carmen
- Flights to Acapulco
- Flights to Veracruz
- Flights to Nuevo Vallarta
- Flights to Puebla
- Flights to Tulum
- Flights to Mérida
- Flights to Puerto Morelos
- Flights to Puerto Vallarta
- Flights to Cancun
- Flights to Monterrey