$60 Cheap Flights from Louisville (SDF) to Myrtle Beach (MYR)

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Cheap Flights from Louisville to Myrtle Beach (SDF-MYR)

Prices were available within the past 7 days and start at $60 for one-way flights and $120 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Spirit Airlines
Spirit Airlines
Spirit Airlines
Spirit Airlines
Spirit Airlines
Spirit Airlines
Southwest Airlines
Delta
American Airlines
United
Flights from Louisville (SDF) to Myrtle Beach (MYR)
Origin airport
Louisville Intl.
Destination airport
Myrtle Beach Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, Spirit Airlines, United
Roundtrip price
$120
Distance
492 mi

Louisville to Myrtle Beach Flights

The cheapest times to fly from Louisville to Myrtle Beach

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Louisville to Myrtle Beach are during the month of May. You can find some of the cheapest flights from Louisville to Myrtle Beach with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Louisville to Myrtle Beach

Sunday is one of the best days to book for cheap flights from Louisville to Myrtle Beach: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Louisville to Myrtle Beach

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Louisville to Myrtle Beach in 2025. You can also book with separate airlines for your outbound and return journeys, from $60 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Louisville to Myrtle Beach flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Louisville to Myrtle Beach airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Louisville Intl. Airport (SDF) to Myrtle Beach Intl. Airport (MYR) cost?
Book cheap return fares starting at $120 from Louisville Intl. Airport (SDF) to Myrtle Beach Intl. Airport (MYR). This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Spirit Airlines flight leaving SDF on May 17 2025 and touching down at MYR. The price was last updated on April 22 2025 and has not changed since.
What is the cheapest month to fly from SDF to MYR?
The cheapest flights from SDF to MYR are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from SDF to MYR?
Currently, the cheapest airline operating one-way flights from SDF to MYR is Spirit Airlines. You can book a seat on this route from $60. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from SDF on June 8 2025. Prices were last updated on April 22 2025 and have not changed since.
How many flights per day from Louisville Intl. Airport (SDF) to Myrtle Beach Intl. Airport (MYR)?
There aren’t any daily direct flights departing from Louisville Intl. Airport (SDF) to Myrtle Beach Intl. Airport (MYR). But you can opt for flights with layovers. Filter your search on Expedia to include one or more stops, and you’ll be soaring above the clouds in no time at all.
What day of the week has the most flights from SDF to MYR?
Friday is generally the busiest day for flights, while Tuesday is often the quietest.* Remember that flight schedules can change based on various factors, including the season and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Louisville Intl. Airport (SDF) to Myrtle Beach Intl. Airport (MYR)?
To avoid potential delays on the Louisville Intl. Airport (SDF) to Myrtle Beach Intl. Airport (MYR) route, aim to fly before 3 PM. Departures after this time have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Louisville Intl. Airport (SDF) to Myrtle Beach Intl. Airport (MYR) last-minute?
Waiting until just before your trip to book a ticket from SDF to MYR generally means paying more. Although you may find some last-minute deals, they aren’t always guaranteed. Keep your travel schedule open for a better chance of snagging a bargain.
Is it cheaper to book a SDF to MYR flight and hotel package?
Compared with arranging hotels and flights separately, booking a SDF to MYR flight and hotel package with Expedia could result in significant savings. Better still, managing everything in one place will take the hassle out of planning your trip. Just secure your flights and choose from our extensive range of stays, then customize your trip with extras like activities and car rentals.
Can I cancel or change the date of my flight from Louisville Intl. Airport (SDF) to Myrtle Beach Intl. Airport (MYR)?
In most instances, you can reschedule or cancel your SDF to MYR flight. However, additional charges may apply, especially if you booked more than 24 hours ago. Double-check your itinerary for the airline’s fees and rules on flight changes, or if you’d like more details, go to our Customer Service portal.

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