$356 Cheap Flights from Santiago (SCL) to Houston (HOU)

View $356 flight on Sun, Jun 8, 2025Opens in a new window

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Find available prices by choosing your travel dates.

Cheap Flights from Santiago to Houston (SCL-HOU)

Prices were available within the past 7 days and start at $356 for one-way flights and $678 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
Wed, Jul 23 - Sun, Aug 24
SCL
Santiago
IAH
Houston
$678 Roundtrip, found 2 days ago
$678
Roundtrip
found 2 days ago
Select avianca flight, departing Wed, Jul 23 from Santiago to Houston, returning Sun, Aug 24, priced at $678 found 2 days ago
avianca
Tue, Jul 22 - Tue, Aug 12
SCL
Santiago
IAH
Houston
$682 Roundtrip, found 1 hour ago
$682
Roundtrip
found 1 hour ago
Select avianca flight, departing Tue, Jul 22 from Santiago to Houston, returning Tue, Aug 12, priced at $682 found 1 hour ago
avianca
Tue, Jul 22 - Tue, Aug 12
SCL
Santiago
IAH
Houston
$699 Roundtrip, found 1 hour ago
$699
Roundtrip
found 1 hour ago
Select avianca flight, departing Tue, Jul 22 from Santiago to Houston, returning Tue, Aug 12, priced at $699 found 1 hour ago
avianca
Tue, May 6 - Tue, May 13
SCL
Santiago
IAH
Houston
$702 Roundtrip, found 1 day ago
$702
Roundtrip
found 1 day ago
Select avianca flight, departing Tue, May 6 from Santiago to Houston, returning Tue, May 13, priced at $702 found 1 day ago
avianca
Mon, Jul 7 - Mon, Sep 8
SCL
Santiago
IAH
Houston
$711 Roundtrip, found 8 hours ago
$711
Roundtrip
found 8 hours ago
Select avianca flight, departing Mon, Jul 7 from Santiago to Houston, returning Mon, Sep 8, priced at $711 found 8 hours ago
avianca
Thu, May 8 - Mon, May 12
SCL
Santiago
IAH
Houston
$719 Roundtrip, found 2 days ago
$719
Roundtrip
found 2 days ago
Select avianca flight, departing Thu, May 8 from Santiago to Houston, returning Mon, May 12, priced at $719 found 2 days ago
Air Canada
Tue, Oct 28 - Tue, Nov 18
SCL
Santiago
IAH
Houston
$1,102 Roundtrip, found 1 day ago
$1,102
Roundtrip
found 1 day ago
Select Air Canada flight, departing Tue, Oct 28 from Santiago to Houston, returning Tue, Nov 18, priced at $1,102 found 1 day ago
American Airlines
Thu, Jun 26 - Tue, Nov 25
SCL
Santiago
IAH
Houston
$1,364 Roundtrip, just found
$1,364
Roundtrip
just found
Select American Airlines flight, departing Thu, Jun 26 from Santiago to Houston, returning Tue, Nov 25, priced at $1,364 just found
Delta
Thu, Jun 26 - Tue, Nov 25
SCL
Santiago
IAH
Houston
$1,364 Roundtrip, just found
$1,364
Roundtrip
just found
Select Delta flight, departing Thu, Jun 26 from Santiago to Houston, returning Tue, Nov 25, priced at $1,364 just found
LATAM Airlines Group
Thu, Jun 26 - Tue, Nov 25
SCL
Santiago
IAH
Houston
$1,416 Roundtrip, just found
$1,416
Roundtrip
just found
Select LATAM Airlines Group flight, departing Thu, Jun 26 from Santiago to Houston, returning Tue, Nov 25, priced at $1,416 just found
Flights from Santiago (SCL) to Houston (IAH)
Origin airport
Arturo Merino Benitez
Destination airport
George Bush Intercontinental
Airlines serving
American Airlines, Delta, LATAM Airlines Group
Roundtrip price
$678
Distance
4663 mi

Santiago to Houston Flights

The cheapest times to fly from Santiago to Houston

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santiago to Houston are during the month of July. You can find some of the cheapest flights from Santiago to Houston with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Santiago to Houston

Sunday is one of the best days to book for cheap flights from Santiago to Houston: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Santiago to Houston

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santiago to Houston in 2025. You can also book with separate airlines for your outbound and return journeys, from $356 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santiago to Houston flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santiago to Houston airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Arturo Merino Benitez Airport (SCL) to William P. Hobby Airport (HOU) cost?
Discover the latest flight deals from SCL to HOU by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from SCL to HOU?
The cheapest flights from SCL to HOU are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from SCL to HOU?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from SCL to HOU. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Arturo Merino Benitez Airport (SCL) to William P. Hobby Airport (HOU)?
There aren’t any daily nonstop flights available from Arturo Merino Benitez Airport (SCL) to William P. Hobby Airport (HOU). But you can book flights with layovers. Filter your search on Expedia to include one or more stops, and you’ll be on your way in no time.
What day of the week has the most flights from SCL to HOU?
You’ll generally find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Arturo Merino Benitez Airport (SCL) to William P. Hobby Airport (HOU)?
Choose a flight from Arturo Merino Benitez Airport (SCL) to William P. Hobby Airport (HOU) that leaves before 3 PM to reduce the likelihood of delays and cancellations. Departures after this time are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
What airports do you fly into for Houston from Arturo Merino Benitez Airport (SCL)?
Check out your flight options from Arturo Merino Benitez Airport (SCL) to George Bush Intercontinental Airport (IAH). This is the only airport in Houston you can jet into if you’re taking a direct flight.
Is it cheaper to buy a plane ticket from Arturo Merino Benitez Airport (SCL) to William P. Hobby Airport (HOU) last-minute?
Booking your flight from SCL to HOU just before your journey is generally more expensive. However, if there’s some wiggle room with your schedule, you could land a cheap last-minute fare.
Is it cheaper to book a SCL to HOU flight and hotel package?
Compared with arranging hotels and flights separately, booking a SCL to HOU flight and hotel package with Expedia could lead to significant savings. Better yet, having it all in one place takes the hassle out of planning your trip. Just pick your flights and select from our wide range of stays, then tailor your trip with other add-ons like activities and car rentals.
Can I cancel or change the date of my flight from Arturo Merino Benitez Airport (SCL) to William P. Hobby Airport (HOU)?
Generally, it’s possible to cancel or reschedule your SCL to HOU flight. However, for bookings made more than 24 hours ago, additional charges may apply. Check your airline’s policies in your itinerary to see what changes are allowed and whether any costs are involved. You’ll also find further details on our Customer Service portal.

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*Available to One Key members.