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Cheap Flights from Santiago to Rome (SCL-FCO)
Prices were available within the past 7 days and start at $501 for one-way flights and $832 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.










Origin airport | Arturo Merino Benitez |
Destination airport | Fiumicino - Leonardo da Vinci Intl. |
Airlines serving | Aerolineas Argentinas, Aeromexico, Air Canada, Air France, American Airlines, British Airways, Delta, Iberia, KLM, LATAM Airlines Group, Turkish Airlines, United |
Roundtrip price | $831 |
Distance | 7388 mi |
Santiago to Rome Flights
The cheapest times to fly from Santiago to Rome
On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santiago to Rome are during the month of November. You can find some of the cheapest flights from Santiago to Rome with Expedia's search tool and vast selection of airlines.
The best time to book a flight from Santiago to Rome
Sunday is one of the best days to book for cheap flights from Santiago to Rome: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.
How to find cheap round-trip tickets from Santiago to Rome
Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santiago to Rome in 2025. You can also book with separate airlines for your outbound and return journeys, from $501 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.
Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santiago to Rome flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.
You could also save big by booking one of Expedia's vacation packages. Bundling together your Santiago to Rome airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.
*Terms apply.
Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.
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Flights
- LATAM Airlines Group Santiago (SCL) to New York (JFK) flights
- LATAM Airlines Group Santiago (SCL) to Punta Arenas (PUQ) flights
- Swiss International Air Lines Chicago (ORD) to Rome (FCO) flights
- ITA Airways New York (JFK) to Rome (FCO) flights
- British Airways Denver (DEN) to Rome (FCO) flights
- TAP Portugal Miami (MIA) to Rome (FCO) flights
- LATAM Airlines Group Santiago (SCL) to Miami (MIA) flights
- Iberia Santiago (SCL) to Barcelona (BCN) flights
- Flights to Palermo
- Flights to Naples
- Flights to Positano
- Flights to Turin
- Flights to Lucca
- Flights to Cortina d'Ampezzo
- Flights to Amalfi
- Flights to Como
- Flights to Sorrento
- Flights to Bari
- Flights to Matera
- Flights to Verona
- Flights to Florence
- Flights to Catania
- Flights to Rome
- Flights to Genoa
- Flights to Bologna
- Flights to Milan
- Flights to Taormina
- Flights to Venice
- Flights from Santiago (SCL) to Rio de Janeiro (GIG)
- Flights from Rome (FCO) to Palermo (PMO)
- Flights from Santiago (SCL) to New York (LGA)
- Flights from Rome (FCO) to Paris (CDG)
- Flights from Rome (FCO) to New York (JFK)
- Flights from Santiago (SCL) to New York (JFK)
- Flights from Santiago (SCL) to Newark Liberty Intl. Airport (EWR)
- Flights from Santiago (SCL) to Punta Arenas (PUQ)
- Flights from Santiago (SCL) to Rio de Janeiro (SDU)
- Flights from Atlanta (ATL) to Rome (FCO)
- Flights from Washington (IAD) to Rome (FCO)
- Flights from Santiago (SCL) to Florianópolis (FLN)
- Flights from Washington (DCA) to Rome (FCO)
- Flights from Miami (MIA) to Rome (FCO)
- Flights from Houston (IAH) to Rome (FCO)
- Flights from Phoenix (PHX) to Rome (FCO)
- Flights from San Francisco (SFO) to Rome (FCO)
- Flights from London (LHR) to Rome (FCO)
- Flights from Los Angeles (LAX) to Rome (FCO)
- Flights from New York (LGA) to Rome (FCO)
- Flights from Beirut (BEY) to Rome (FCO)
- Flights from Orlando (MCO) to Rome (FCO)
- Flights from Seattle (SEA) to Rome (FCO)
- Flights from Chicago (ORD) to Rome (FCO)
- Flights from San Diego (SAN) to Rome (FCO)
- Flights from Dallas (DFW) to Rome (FCO)
- Flights from Fort Lauderdale (FLL) to Rome (FCO)
- Flights from New York (JFK) to Rome (FCO)
- Flights from Detroit (DTW) to Rome (FCO)
- Flights from Philadelphia (PHL) to Rome (FCO)
- Flights from Paris (CDG) to Rome (FCO)
- Flights from Athens (ATH) to Rome (FCO)
- Flights from Newark Liberty Intl. Airport (EWR) to Rome (FCO)
- Flights from Boston (BOS) to Rome (FCO)
- Flights from Raleigh (RDU) to Rome (FCO)
- Flights from Barcelona (BCN) to Rome (FCO)
- Flights from Denver (DEN) to Rome (FCO)
- Flights from Rome (FCO) to London (LHR)
- Flights from Santiago (SCL) to Los Angeles (LAX)
- Flights from Rome (FCO) to Los Angeles (LAX)
- Flights from Santiago (SCL) to Miami (MIA)
- Flights from Santiago (SCL) to Buenos Aires (AEP)
- Flights from Rome (FCO) to Venice (VCE)
- Flights from Rome (FCO) to Athens (ATH)
- Flights from Santiago (SCL) to Barcelona (BCN)
- Flights from Santiago (SCL) to Mexico City (MEX)
- Aerolineas Argentinas
- Air Canada
- avianca
- Delta
- LATAM Airlines Group
- KLM
- SKY AIRLINE
- Iberia
- Copa
- British Airways
- United
- GOL Linhas Aereas S.A.
- Aeromexico
- Air France
- American Airlines
- Turkish Airlines