
Popular airlines from Santiago Intl. Airport (SCL) to Antofagasta (ANF-Cerro Moreno Intl.)
- LATAM Airlines Group
LATAM Airlines Group
- Sky Airlines
Sky Airlines
- B & H Airlines
B & H Airlines
- Plan, book, fly with confidence
- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 30% on select hotels after you book a flight*
Cheap Flights from Santiago to Antofagasta (SCL-ANF)
Prices were available within the past 7 days and start at $35 for one-way flights and $70 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.










Frequently asked questions
Travel information
Travel information
Origin airport | Arturo Merino Benitez |
Destination airport | Cerro Moreno Intl. |
Airlines serving | Jetsmart SPA, LATAM Airlines Group, SKY AIRLINE |
Roundtrip price | $70 |
Distance | 687 mi |
Book with confidence
Book with confidence
The cheapest times to fly from Santiago to Antofagasta
On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santiago to Antofagasta are during the month of May. You can find some of the cheapest flights from Santiago to Antofagasta with Expedia's search tool and vast selection of airlines.
The best time to book a flight from Santiago to Antofagasta
Sunday is one of the best days to book for cheap flights from Santiago to Antofagasta: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.
How to find cheap round-trip tickets from Santiago to Antofagasta
Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santiago to Antofagasta in 2025. You can also book with separate airlines for your outbound and return journeys, from $35 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.
Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santiago to Antofagasta flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.
You could also save big by booking one of Expedia's vacation packages. Bundling together your Santiago to Antofagasta airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.
*Terms apply.
Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.
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Be inspired and discover more with Expedia
Lodging
- La Chimba Hotels
- Hotels with Hot Tubs in Antofagasta Region
- Hotels with Restaurants in Antofagasta Region
- Lodges in Antofagasta Region
- Antofagasta Region Hotels
- Antofagasta Province Hotels
- Resorts & Hotels with Spas in Antofagasta Region
- Hotels with smoking rooms in Antofagasta Region
- Cabin Rentals in Antofagasta Region
- Apartments in Antofagasta Region
- Casino Hotels in Antofagasta Region
- Aparthotels in Antofagasta Region
- Resorts in Antofagasta Region
- Hotels near Plaza Colon
- Antofagasta Hotels
- Apartments in Antofagasta
- Historic Hotels in Antofagasta
- Casino Hotels in Antofagasta
- 5 Star Hotels in Antofagasta
- Hotels & Resorts for Couples in Antofagasta
- Resorts & Hotels with Spas
- Pet-friendly Hotels in Antofagasta
- Hotel Wedding Venues Hotels in Antofagasta
- Hotels near El Tatio
- Hotels near Catholic University of the North
- Mejillones Hotels
- Apartments in Mejillones
- Hotel with a Concierge Hotels in Mejillones
- Hotels with Free Breakfast Hotels in Antofagasta Region
- Beach Hotels in Antofagasta Region
- Hotel Wedding Venues Hotels in Antofagasta Region
- B&B in Antofagasta
- Hotels with Suites Hotels in Antofagasta Region
- Historical District Hotels
- Hotels on the River Hotels in Antofagasta Region
- Hotels near University of Antofagasta
- 1 Star Hotels in La Chimba
- Hotels with smoking rooms in Antofagasta
- 3 Star Hotels in Antofagasta
- Hotels near Paseo del Mar Boardwalk
- Hotels near Huanchaca Ruins Cultural Park
- Hotels with Fireplaces Hotels in Antofagasta Region
- Hotels on the Lake Hotels in Antofagasta Region
- Waterpark Hotels in Antofagasta Region
- Oceanfront Hotels in Antofagasta Region
- Fishing Resorts & Hotels in Antofagasta Region
- Hotels near Central Market
- Hotels near Balneario Nocturno Beach
- Gay friendly Hotels in Antofagasta
- Hotels with a Swim-up Bar Hotels in Antofagasta Region
- Hotels with a Pool Hotels in Antofagasta
Packages
- Tropic of Capricorn Monument
- La Portada Natural Monument
- Visit La Chimba
- La Chimba Vacations
- Antofagasta Fish Market
- Historical Dock of Antofagasta
- Visit Antofagasta Region
- Plaza Colon
- Antofagasta Region Vacations
- Antofagasta Municipal Theater
- Visit Antofagasta
- Antofagasta Vacations
- El Tatio
- Paseo del Mar Boardwalk
- Huanchaca Ruins Cultural Park
- Visit Mejillones
- Mejillones Park
- Balneario Nocturno Beach
- Mejillones Stadium
- Antofagasta Regional Stadium
Cars
- Car rentals near Antofagasta
- Sixt Rental Cars in Antofagasta
- Hertz Rental Cars in Antofagasta
- Europcar Rental Cars in Antofagasta
- Alamo Rent A Car Rental Cars in Antofagasta
- Car rentals near Mejillones
- Ace Rental Cars in Antofagasta
- Car rentals near El Tatio
- Car rentals near La Portada Natural Monument
- Economy Car Rentals in Antofagasta
- Rhodium Rental Cars in Antofagasta
- Payless Rental Cars in Antofagasta
- Car rentals near Antofagasta Regional Stadium
- Budget Israel Rental Cars in Antofagasta
- Car rentals near Antofagasta Cathedral
- Owners Rental Cars in Antofagasta
- Mini Car Rentals in Antofagasta