$227 Cheap Flights from San Antonio (SAT) to Panama City (PTY)

View $227 flight on Sun, Jul 20, 2025Opens in a new window

Popular airlines from San Antonio International Airport (SAT) to Tocumen Intl. Airport (PTY)

Find available prices by choosing your travel dates.

Cheap Flights from San Antonio to Panama City (SAT-PTY)

Prices were available within the past 7 days and start at $227 for one-way flights and $479 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Jan 14 - Wed, Jan 21
SAT
San Antonio
PTY
Panama City
$479 Roundtrip, found 10 hours ago
$479
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Wed, Jan 14 from San Antonio to Panama City, returning Wed, Jan 21, priced at $479 found 10 hours ago
Delta
Tue, Jul 8 - Tue, Jul 22
SAT
San Antonio
PTY
Panama City
$479 Roundtrip, just found
$479
Roundtrip
just found
Select Delta flight, departing Tue, Jul 8 from San Antonio to Panama City, returning Tue, Jul 22, priced at $479 just found
United
Tue, Jul 8 - Tue, Jul 22
SAT
San Antonio
PTY
Panama City
$479 Roundtrip, just found
$479
Roundtrip
just found
Select United flight, departing Tue, Jul 8 from San Antonio to Panama City, returning Tue, Jul 22, priced at $479 just found
American Airlines
Tue, Jul 8 - Tue, Jul 22
SAT
San Antonio
PTY
Panama City
$484 Roundtrip, just found
$484
Roundtrip
just found
Select American Airlines flight, departing Tue, Jul 8 from San Antonio to Panama City, returning Tue, Jul 22, priced at $484 just found
United
Tue, Jul 8 - Tue, Jul 22
SAT
San Antonio
PTY
Panama City
$486 Roundtrip, just found
$486
Roundtrip
just found
Select United flight, departing Tue, Jul 8 from San Antonio to Panama City, returning Tue, Jul 22, priced at $486 just found
Delta
Tue, Jul 8 - Tue, Jul 22
SAT
San Antonio
PTY
Panama City
$489 Roundtrip, just found
$489
Roundtrip
just found
Select Delta flight, departing Tue, Jul 8 from San Antonio to Panama City, returning Tue, Jul 22, priced at $489 just found
American Airlines
Tue, Aug 19 - Thu, Sep 18
SAT
San Antonio
PTY
Panama City
$491 Roundtrip, found 2 days ago
$491
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Aug 19 from San Antonio to Panama City, returning Thu, Sep 18, priced at $491 found 2 days ago
American Airlines
Mon, Jun 23 - Thu, Jul 3
SAT
San Antonio
PTY
Panama City
$492 Roundtrip, found 12 hours ago
$492
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Mon, Jun 23 from San Antonio to Panama City, returning Thu, Jul 3, priced at $492 found 12 hours ago
United
Tue, Jul 8 - Tue, Jul 22
SAT
San Antonio
PTY
Panama City
$492 Roundtrip, just found
$492
Roundtrip
just found
Select United flight, departing Tue, Jul 8 from San Antonio to Panama City, returning Tue, Jul 22, priced at $492 just found
Copa
Thu, Jul 10 - Mon, Jul 21
SAT
San Antonio
PTY
Panama City
$1,571 Roundtrip, found 1 hour ago
$1,571
Roundtrip
found 1 hour ago
Select Copa flight, departing Thu, Jul 10 from San Antonio to Panama City, returning Mon, Jul 21, priced at $1,571 found 1 hour ago

Frequently asked questions

How much does a flight from San Antonio Intl. Airport (SAT) to Tocumen Intl. Airport (PTY) cost?
Discover the latest flight deals from SAT to PTY by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from SAT to PTY?
The cheapest flights from SAT to PTY are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from SAT to PTY?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from SAT to PTY. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from San Antonio Intl. Airport (SAT) to Tocumen Intl. Airport (PTY)?
You’ll need to hop on a flight with a layover if you’re traveling from San Antonio Intl. Airport (SAT) to Tocumen Intl. Airport (PTY). Direct flights don’t operate daily on this route. However, just filter your search to include one or two stops to find an option that works for you.
What day of the week has the most flights from SAT to PTY?
You’ll generally find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from San Antonio Intl. Airport (SAT) to Tocumen Intl. Airport (PTY)?
To avoid possible delays on the San Antonio Intl. Airport (SAT) to Tocumen Intl. Airport (PTY) route, aim to travel before 3 PM. Later flights are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from San Antonio Intl. Airport (SAT) to Tocumen Intl. Airport (PTY) last-minute?
Last-minute bookings from SAT to PTY are typically more expensive. To secure the cheapest rates, start looking for flights as early as possible. That said, if your travel plans are flexible, you may score a cheap fare right before your journey.
Is it cheaper to book a SAT to PTY flight and hotel package?
Compared with arranging flights and hotels separately, booking a SAT to PTY flight and hotel package with Expedia could lead to significant savings. Better yet, having it all in one place will take the hassle out of travel planning. Simply secure your flights and choose from our extensive range of hotels, then personalize your trip with extras like activities, tours and car rentals.
Can I cancel or change the date of my flight from San Antonio Intl. Airport (SAT) to Tocumen Intl. Airport (PTY)?
Generally, it’s possible to reschedule or cancel your SAT to PTY flight. However, for bookings made more than 24 hours ago, additional fees may apply. Check your airline’s policies in your itinerary to see what changes are allowed and if any costs are involved. You’ll also find more details on our Customer Service portal.
*Available to One Key members.