$95 Cheap Flights from San Diego (SAN) to Knoxville (TYS)

Bundle Your Flight + Hotel & Save!

Flight deals we found

These prices are lower than our typical predictions for similar flights.
65% less than typical
$382
Roundtrip per traveler
Wed, May 8 - Mon, May 13
UnitedUnited
8h 47m
10:29pm
10:16am
+1
SAN
1 stop • 3h in ORD
TYS
Found 14 hours ago
65% less than typical
$252
Roundtrip per traveler
Sat, Jun 1 - Tue, Jun 4
American AirlinesAmerican Airlines
9h 6m
10:31pm
10:37am
+1
SAN
1 stop • 3h 6m in CLT
TYS
Found 4 hours ago
55% less than typical
$302
Roundtrip per traveler
Wed, May 15 - Wed, May 22
UnitedUnited
10h 12m
9:14pm
10:26am
+1
SAN
1 stop • 3h 31m in IAD
TYS
Found 16 hours ago
45% less than typical
$387
Roundtrip per traveler
Thu, Jun 6 - Wed, Jun 12
DeltaDelta
7h 38m
11:15am
9:53pm
SAN
1 stop • 2h 28m in ATL
TYS
Found 17 hours ago
45% less than typical
$413
Roundtrip per traveler
Thu, May 2 - Thu, May 9
UnitedUnited
10h 12m
9:14pm
10:26am
+1
SAN
1 stop • 3h 31m in IAD
TYS
Found 11 hours ago

Featured airlines

Top nine airline logos for desktop

    Plan, book, fly with confidence
  • trending down icon
    Be in the know
    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon
    Book smarter
    Save up to 30% on select hotels after you book a flight*
  • one key icon
    Earn twice
    Earn your airline miles on top of our OneKeyCash

Cheap Flights from San Diego to Knoxville (SAN-TYS)

Prices were available within the past 7 days and start at $95 for one-way flights and $189 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Frontier Airlines
Frontier Airlines
American Airlines
American Airlines
American Airlines
Frontier Airlines
Frontier Airlines
Frontier Airlines
Frontier Airlines
Flights from San Diego (SAN) to Knoxville (TYS)
Origin airport
San Diego Intl.
Destination airport
McGhee Tyson
Airlines serving
Alaska Airlines, American Airlines, Delta, Frontier Airlines, United
Roundtrip price
$189
Distance
1898 mi

San Diego to Knoxville Flights

Whether you’re looking for a grand adventure or just want to get away for a last-minute break, flights from San Diego to Knoxville offer the perfect respite. Not only does exploring Knoxville provide the chance to make some magical memories, dip into delectable dishes, and tour the local landmarks, but the cheap airfare means you won’t bust your budget. So no matter whether your ideal itinerary involves flying one way, non-stop, or round trip, you’re bound to find flights that match your schedule on Expedia, and at prices that won’t shock your wallet.

Bagging a cheap flight from San Diego to Knoxville may mean more dollars to spend on for one-of-a-kind souvenirs when you arrive, but it doesn’t mean you have to skimp on your travel experience, as Expedia offers a sizzling selection of cheap airlines that’ll put you in your happy place on their planes, whether that’s getting lost in a hair-raising airport thriller, dreaming on the passing landscape over a glass of bubbly, or jotting down your vacation bucket list at 38,000 feet. There’s also bound to be plenty of opportunities to snap a few photos of the high life that will make your friends green with envy. After all, enjoying the journey is part of the fun.

With so many affordable flights and so many wonderful adventures awaiting you, there’s no reason to put off booking a fantastic flight from to today. So don’t leave it to the last minute to make your dream trip a reality: pack your bags with your go-to travel accessories, put together your list of must-see attractions and can’t-miss activities, and get ready to broaden your horizons – with Expedia, the wonders of Knoxville are only a plane trip away. Book your travel arrangements with us today!

If you would like to book flights to Knoxville more flexibly many prefer to purchase one-way tickets with options to take different airlines. A one way ticket to Knoxville is $95 now!

Frequently asked questions

How much is a one-way flight from San Diego Airport to TYS?
You can pick up one-way San Diego flights to Knoxville starting from just $101. This data is based on the lowest price found on Expedia for this journey leaving in the next three months and was updated on May 1 2024 and has not changed since. This airfare is for an American Airlines flight, setting off from San Diego Intl. Airport (SAN) on May 29 2024 and arriving at Knoxville Airport.
Is it cheaper to buy a plane ticket from San Diego Airport to Knoxville Airport last minute?
Being spontaneous is an awesome way to discover the world, but it isn’t necessarily the ideal way to find a bargain flight. Consider booking your San Diego Airport to Knoxville Airport trip in advance rather than waiting till the last minute. Based on flight pricing and demand studies in 2022, we have found that the best time to book domestic flights is between 28 – 35 days ahead of the departure date, and international flights three to four months in advance. Leave your spontaneous side for when you’re exploring Knoxville Airport!
What is the cheapest airline flying from SAN to TYS in the next 90 days?
The cheapest carrier flying from San Diego to Knoxville found on Expedia is American Airlines, with fares starting at $101. This price is based on fares found on Expedia with a departure date within the next 90 days. The flight leaves San Diego Airport on May 29 2024 and touches down at Knoxville Airport. Pricing information was updated on May 1 2024 and has not changed since.
What's the cheapest price for a flight from San Diego Airport to TYS next month?
With a one-way flight from San Diego to Knoxville on offer for just $138, you’ll have more moolah to splash on fun adventures. This fare was found after searching through all available flights on Expedia within the next 30 days. This particular service takes off from San Diego Airport on May 28 2024, lands at TYS and is with United. The price of this flight was last updated on May 1 2024 and has not changed since.
What airports do you fly into for Knoxville from San Diego County?
With McGhee Tyson Airport (TYS), Gatlinburg, TN (GKT-Gatlinburg - Pigeon Forge) and Morristown, TN (MOR-Moore-Murrell) to pick from, making your way from San Diego County to Knoxville is a cinch. The city’s main gateway, McGhee Tyson Airport (TYS), is approximately 12 mi south of the center. Apart from the price of tickets, consider things like public transportation options from the airport and the distance to your hotel when choosing where to fly into. Get your Knoxville vacation off to a terrific start by checking out Ijams Nature Center and Knoxville Zoological Gardens.
Can I change the date of my flight from San Diego Airport to McGhee Tyson Airport (TYS)?
You can easily make changes to your San Diego Airport to Knoxville Airport journey through the Expedia Trips portal. Before you make any amendments, look over the rules and restrictions in your itinerary to find out what the airline will let you do and what charges may apply. Some airlines have a change fee per person, plus any difference in fare prices. However, if you booked in the last 24 hours, you may be able to cancel for free and organize new flights. You can also visit our Customer Service portal for more info and to connect with our Virtual Agent.
*Available to One Key members.