$144 Cheap Flights from San Diego (SAN) to Panama City (ECP)

View $144 flight on Thu, May 29, 2025Opens in a new window

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Find available prices by choosing your travel dates.

Cheap Flights from San Diego to Panama City (SAN-ECP)

Prices were available within the past 7 days and start at $144 for one-way flights and $297 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, May 28 - Tue, Jun 10
SAN
San Diego
ECP
Panama City
$297 Roundtrip, just found
$297
Roundtrip
just found
Select American Airlines flight, departing Wed, May 28 from San Diego to Panama City, returning Tue, Jun 10, priced at $297 just found
American Airlines
Wed, May 28 - Tue, Jun 10
SAN
San Diego
ECP
Panama City
$301 Roundtrip, just found
$301
Roundtrip
just found
Select American Airlines flight, departing Wed, May 28 from San Diego to Panama City, returning Tue, Jun 10, priced at $301 just found
Delta
Wed, May 28 - Tue, Jun 10
SAN
San Diego
ECP
Panama City
$307 Roundtrip, just found
$307
Roundtrip
just found
Select Delta flight, departing Wed, May 28 from San Diego to Panama City, returning Tue, Jun 10, priced at $307 just found
United
Wed, May 28 - Tue, Jun 10
SAN
San Diego
ECP
Panama City
$307 Roundtrip, just found
$307
Roundtrip
just found
Select United flight, departing Wed, May 28 from San Diego to Panama City, returning Tue, Jun 10, priced at $307 just found
Delta
Wed, May 28 - Tue, Jun 10
SAN
San Diego
ECP
Panama City
$312 Roundtrip, just found
$312
Roundtrip
just found
Select Delta flight, departing Wed, May 28 from San Diego to Panama City, returning Tue, Jun 10, priced at $312 just found
United
Wed, May 28 - Tue, Jun 10
SAN
San Diego
ECP
Panama City
$312 Roundtrip, just found
$312
Roundtrip
just found
Select United flight, departing Wed, May 28 from San Diego to Panama City, returning Tue, Jun 10, priced at $312 just found
United
Wed, May 28 - Tue, Jun 10
SAN
San Diego
ECP
Panama City
$317 Roundtrip, just found
$317
Roundtrip
just found
Select United flight, departing Wed, May 28 from San Diego to Panama City, returning Tue, Jun 10, priced at $317 just found
American Airlines
Wed, May 28 - Mon, Jun 2
SAN
San Diego
ECP
Panama City
$320 Roundtrip, found 3 hours ago
$320
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Wed, May 28 from San Diego to Panama City, returning Mon, Jun 2, priced at $320 found 3 hours ago
United
Wed, May 28 - Tue, Jun 10
SAN
San Diego
ECP
Panama City
$325 Roundtrip, just found
$325
Roundtrip
just found
Select United flight, departing Wed, May 28 from San Diego to Panama City, returning Tue, Jun 10, priced at $325 just found
Southwest Airlines
Wed, Jun 11 - Wed, Jun 18
SAN
San Diego
ECP
Panama City
$332 Roundtrip, found 7 hours ago
$332
Roundtrip
found 7 hours ago
Select Southwest Airlines flight, departing Wed, Jun 11 from San Diego to Panama City, returning Wed, Jun 18, priced at $332 found 7 hours ago
Flights from San Diego (SAN) to Panama City (ECP)
Origin airport
San Diego Intl.
Destination airport
Northwest Florida Beaches Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$296
Distance
1849 mi

San Diego to Panama City Flights

The cheapest times to fly from San Diego to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from San Diego to Panama City are during the month of May. You can find some of the cheapest flights from San Diego to Panama City with Expedia's search tool and vast selection of airlines.

The best time to book a flight from San Diego to Panama City

Sunday is one of the best days to book for cheap flights from San Diego to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from San Diego to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from San Diego to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $144 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap San Diego to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your San Diego to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from San Diego Intl. Airport (SAN) to Northwest Florida Beaches Intl. Airport (ECP) cost?
Discover the latest flight deals from SAN to ECP by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from SAN to ECP?
The cheapest flights from SAN to ECP are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from SAN to ECP?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from SAN to ECP. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from San Diego Intl. Airport (SAN) to Northwest Florida Beaches Intl. Airport (ECP)?
There aren’t any daily nonstop flights from San Diego Intl. Airport (SAN) to Northwest Florida Beaches Intl. Airport (ECP). But you can choose flights with layovers. Filter your search on Expedia to include one or more stops, and you’ll be cruising above the clouds in no time at all.
What day of the week has the most flights from SAN to ECP?
Usually you’ll find the most flight options available on a Friday. Tuesdays tend to be the quietest.* However, this can change based on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from San Diego Intl. Airport (SAN) to Northwest Florida Beaches Intl. Airport (ECP)?
To avoid potential delays on the San Diego Intl. Airport (SAN) to Northwest Florida Beaches Intl. Airport (ECP) route, aim to fly before 3 PM. Later flights are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from San Diego Intl. Airport (SAN) to Northwest Florida Beaches Intl. Airport (ECP) last-minute?
Booking your flight from SAN to ECP shortly before your trip is usually more expensive. But if you’re flexible with your schedule, you could bag a cheap last-minute fare.
Is it cheaper to book a SAN to ECP flight and hotel package?
Compared with arranging flights and hotels separately, booking a SAN to ECP flight and hotel package with Expedia could lead to significant savings. Better still, having everything in one convenient place will take the hassle out of travel planning. Simply secure your flights and select from our extensive range of hotels, then personalize your trip with extras like activities and car rentals.
Can I cancel or change the date of my flight from San Diego Intl. Airport (SAN) to Northwest Florida Beaches Intl. Airport (ECP)?
Usually, it’s possible to cancel or reschedule your SAN to ECP flight. However, if it’s been more than 24 hours since booking, additional charges may apply. Check your airline’s policies in your itinerary to see what changes are possible and if any costs are involved. You’ll also find more details on our Customer Service portal.

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*Available to One Key members.