$230 Cheap Flights from Fort Myers (RSW) to La Crosse (LSE)

View $230 flight on Tue, May 6, 2025Opens in a new window

Popular airlines from Southwest Florida Intl. Airport (RSW) to La Crosse, WI (LSE-La Crosse Municipal)

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Find available prices by choosing your travel dates.

Cheap Flights from Fort Myers to La Crosse (RSW-LSE)

Prices were available within the past 7 days and start at $230 for one-way flights and $492 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sun, Nov 23 - Thu, Nov 27
RSW
Fort Myers
LSE
La Crosse
$492 Roundtrip, found 5 days ago
$492
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sun, Nov 23 from Fort Myers to La Crosse, returning Thu, Nov 27, priced at $492 found 5 days ago
American Airlines
Sun, Nov 23 - Thu, Nov 27
RSW
Fort Myers
LSE
La Crosse
$508 Roundtrip, found 5 days ago
$508
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sun, Nov 23 from Fort Myers to La Crosse, returning Thu, Nov 27, priced at $508 found 5 days ago
American Airlines
Wed, May 7 - Sat, May 10
RSW
Fort Myers
LSE
La Crosse
$510 Roundtrip, found 2 days ago
$510
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, May 7 from Fort Myers to La Crosse, returning Sat, May 10, priced at $510 found 2 days ago
American Airlines
Fri, Apr 25 - Sun, Apr 27
RSW
Fort Myers
LSE
La Crosse
$514 Roundtrip, found 4 days ago
$514
Roundtrip
found 4 days ago
Select American Airlines flight, departing Fri, Apr 25 from Fort Myers to La Crosse, returning Sun, Apr 27, priced at $514 found 4 days ago
American Airlines
Tue, May 6 - Sat, May 10
RSW
Fort Myers
LSE
La Crosse
$516 Roundtrip, found 2 days ago
$516
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, May 6 from Fort Myers to La Crosse, returning Sat, May 10, priced at $516 found 2 days ago
American Airlines
Mon, May 5 - Mon, May 12
RSW
Fort Myers
LSE
La Crosse
$528 Roundtrip, found 2 days ago
$528
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, May 5 from Fort Myers to La Crosse, returning Mon, May 12, priced at $528 found 2 days ago
American Airlines
Sun, Nov 23 - Thu, Nov 27
RSW
Fort Myers
LSE
La Crosse
$534 Roundtrip, found 5 days ago
$534
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sun, Nov 23 from Fort Myers to La Crosse, returning Thu, Nov 27, priced at $534 found 5 days ago
American Airlines
Mon, May 5 - Sat, May 10
RSW
Fort Myers
LSE
La Crosse
$549 Roundtrip, found 2 days ago
$549
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, May 5 from Fort Myers to La Crosse, returning Sat, May 10, priced at $549 found 2 days ago
American Airlines
Mon, May 5 - Mon, May 12
RSW
Fort Myers
LSE
La Crosse
$561 Roundtrip, found 2 days ago
$561
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, May 5 from Fort Myers to La Crosse, returning Mon, May 12, priced at $561 found 2 days ago
American Airlines
Mon, May 5 - Mon, May 12
RSW
Fort Myers
LSE
La Crosse
$567 Roundtrip, found 2 days ago
$567
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, May 5 from Fort Myers to La Crosse, returning Mon, May 12, priced at $567 found 2 days ago
Flights from Fort Myers (RSW) to La Crosse (LSE)
Origin airport
Southwest Florida Intl.
Destination airport
La Crosse Municipal
Roundtrip price
$491
Distance
1311 mi

Fort Myers to La Crosse Flights

The cheapest times to fly from Fort Myers to La Crosse

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Fort Myers to La Crosse are during the month of November. You can find some of the cheapest flights from Fort Myers to La Crosse with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Fort Myers to La Crosse

Sunday is one of the best days to book for cheap flights from Fort Myers to La Crosse: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Fort Myers to La Crosse

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Fort Myers to La Crosse in 2025. You can also book with separate airlines for your outbound and return journeys, from $230 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Fort Myers to La Crosse flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Fort Myers to La Crosse airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Southwest Florida Intl. Airport (RSW) to La Crosse Municipal Airport (LSE) cost?
Discover the latest flight deals from RSW to LSE by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from RSW to LSE?
The cheapest flights from RSW to LSE are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from RSW to LSE?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from RSW to LSE. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Southwest Florida Intl. Airport (RSW) to La Crosse Municipal Airport (LSE)?
You’ll need to catch a flight with a layover when traveling from Southwest Florida Intl. Airport (RSW) to La Crosse Municipal Airport (LSE). There are no daily direct flights on this route. However, just filter your search to include one or two stops to find an option that works for you.
What day of the week has the most flights from RSW to LSE?
Usually you’ll find the largest variety of flight choices on a Friday. Tuesdays are often the quietest.* However, this can vary depending on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Southwest Florida Intl. Airport (RSW) to La Crosse Municipal Airport (LSE)?
Choose a flight from Southwest Florida Intl. Airport (RSW) to La Crosse Municipal Airport (LSE) that leaves before 3 PM to reduce the risk of cancellations and delays. Departures after this hour have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Southwest Florida Intl. Airport (RSW) to La Crosse Municipal Airport (LSE) last-minute?
Last-minute fares from RSW to LSE are generally more expensive. For the cheapest rates, start searching for flights early. That said, if your travel plans are flexible, it’s possible to land a cheap fare right before you leave.
Is it cheaper to book a RSW to LSE flight and hotel package?
You can save money by booking a RSW to LSE flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it’s simple to manage it all in one place. Once you’ve selected your ideal flights and accommodations, you can add extras such as tours, car rentals and activities.
Can I cancel or change the date of my flight from Southwest Florida Intl. Airport (RSW) to La Crosse Municipal Airport (LSE)?
If you booked your RSW to LSE flight in the last 24 hours, you may be able to modify or cancel it at no cost. Depending on the airline and the fare type you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for more details.

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*Available to One Key members.