$89 Cheap Flights from Fort Myers (RSW) to Buffalo (BUF)

View $89 flight on Tue, Jun 24, 2025Opens in a new window

Popular airlines from Southwest Florida Intl. Airport (RSW) to Buffalo Niagara Intl. Airport (BUF)

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Find available prices by choosing your travel dates.

Cheap Flights from Fort Myers to Buffalo (RSW-BUF)

Prices were available within the past 7 days and start at $89 for one-way flights and $177 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

JetBlue Airways
Sat, May 24 - Wed, Jun 4
RSW
Fort Myers
BUF
Buffalo
$177 Roundtrip, found 2 hours ago
$177
Roundtrip
found 2 hours ago
Select JetBlue Airways flight, departing Sat, May 24 from Fort Myers to Buffalo, returning Wed, Jun 4, priced at $177 found 2 hours ago
JetBlue Airways
Tue, Jun 24 - Sat, Jul 5
RSW
Fort Myers
BUF
Buffalo
$181 Roundtrip, found 4 hours ago
$181
Roundtrip
found 4 hours ago
Select JetBlue Airways flight, departing Tue, Jun 24 from Fort Myers to Buffalo, returning Sat, Jul 5, priced at $181 found 4 hours ago
JetBlue Airways
Fri, Sep 5 - Tue, Sep 9
RSW
Fort Myers
BUF
Buffalo
$185 Roundtrip, found 6 hours ago
$185
Roundtrip
found 6 hours ago
Select JetBlue Airways flight, departing Fri, Sep 5 from Fort Myers to Buffalo, returning Tue, Sep 9, priced at $185 found 6 hours ago
JetBlue Airways
Sat, May 24 - Tue, Jun 10
RSW
Fort Myers
BUF
Buffalo
$194 Roundtrip, found 2 hours ago
$194
Roundtrip
found 2 hours ago
Select JetBlue Airways flight, departing Sat, May 24 from Fort Myers to Buffalo, returning Tue, Jun 10, priced at $194 found 2 hours ago
JetBlue Airways
Thu, Jun 12 - Fri, Jun 13
RSW
Fort Myers
BUF
Buffalo
$197 Roundtrip, found 3 hours ago
$197
Roundtrip
found 3 hours ago
Select JetBlue Airways flight, departing Thu, Jun 12 from Fort Myers to Buffalo, returning Fri, Jun 13, priced at $197 found 3 hours ago
JetBlue Airways
Tue, Sep 2 - Tue, Sep 9
RSW
Fort Myers
BUF
Buffalo
$198 Roundtrip, found 6 hours ago
$198
Roundtrip
found 6 hours ago
Select JetBlue Airways flight, departing Tue, Sep 2 from Fort Myers to Buffalo, returning Tue, Sep 9, priced at $198 found 6 hours ago
United
Thu, Sep 4 - Tue, Sep 9
RSW
Fort Myers
BUF
Buffalo
$206 Roundtrip, found 6 hours ago
$206
Roundtrip
found 6 hours ago
Select United flight, departing Thu, Sep 4 from Fort Myers to Buffalo, returning Tue, Sep 9, priced at $206 found 6 hours ago
American Airlines
Fri, Aug 8 - Mon, Aug 11
RSW
Fort Myers
BUF
Buffalo
$217 Roundtrip, found 2 hours ago
$217
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Fri, Aug 8 from Fort Myers to Buffalo, returning Mon, Aug 11, priced at $217 found 2 hours ago
Delta
Wed, Jul 9 - Sun, Jul 13
RSW
Fort Myers
BUF
Buffalo
$217 Roundtrip, found 2 hours ago
$217
Roundtrip
found 2 hours ago
Select Delta flight, departing Wed, Jul 9 from Fort Myers to Buffalo, returning Sun, Jul 13, priced at $217 found 2 hours ago
Southwest Airlines
Tue, Jun 10 - Tue, Jun 17
RSW
Fort Myers
BUF
Buffalo
$217 Roundtrip, found 1 day ago
$217
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Tue, Jun 10 from Fort Myers to Buffalo, returning Tue, Jun 17, priced at $217 found 1 day ago
Flights from Fort Myers (RSW) to Buffalo (BUF)
Origin airport
Southwest Florida Intl.
Destination airport
Buffalo Niagara Intl.
Airlines serving
American Airlines, Delta, JetBlue Airways, Southwest Airlines, United
Roundtrip price
$176
Distance
1146 mi

Fort Myers to Buffalo Flights

The cheapest times to fly from Fort Myers to Buffalo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Fort Myers to Buffalo are during the month of May. You can find some of the cheapest flights from Fort Myers to Buffalo with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Fort Myers to Buffalo

Sunday is one of the best days to book for cheap flights from Fort Myers to Buffalo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Fort Myers to Buffalo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Fort Myers to Buffalo in 2025. You can also book with separate airlines for your outbound and return journeys, from $89 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Fort Myers to Buffalo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Fort Myers to Buffalo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Southwest Florida Intl. Airport (RSW) to Buffalo Niagara Intl. Airport (BUF) cost?
Cheap return fares from Southwest Florida Intl. Airport (RSW) to Buffalo Niagara Intl. Airport (BUF) start from $265. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Southwest Airlines flight leaving RSW on May 14 2025 and touching down at BUF. The price was last updated on April 23 2025 and has not changed since.
What is the cheapest month to fly from RSW to BUF?
The cheapest flights from RSW to BUF are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Southwest Florida Intl. Airport (RSW) to Buffalo Niagara Intl. Airport (BUF)?
When jetting out of Southwest Florida Intl. Airport (RSW), you can get on a nonstop flight to Buffalo Niagara Intl. Airport (BUF) with Frontier Airlines.
What is the cheapest airline that flies from RSW to BUF?
Take off from RSW to BUF with Southwest Airlines. This carrier currently has the cheapest one-way fare for this route, starting at $133. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from RSW on June 4 2025. Prices were last updated on April 23 2025 and have not changed since.
How many flights per day from Southwest Florida Intl. Airport (RSW) to Buffalo Niagara Intl. Airport (BUF)?
On average, there’s only 1 direct flight taking off from Southwest Florida Intl. Airport (RSW) to Buffalo Niagara Intl. Airport (BUF) per day. If this isn’t convenient for you, check out flights with layovers. Simply filter your search results on Expedia to include one stop or more to find the next best option.
What are the most popular departure times for flights from Southwest Florida Intl. Airport (RSW) to Buffalo Niagara Intl. Airport (BUF)?
Flights between RSW and BUF tend to be busiest at 8 PM. If you’d like a more relaxed trip and possibly cheaper tickets, look for a departure that’s outside typical rush times.
What day of the week has the most flights from RSW to BUF?
Jet off on a Saturday if you’re after the biggest selection of flights from Southwest Florida Intl. Airport (RSW) to Buffalo Niagara Intl. Airport (BUF).
What is the earliest flight from Southwest Florida Intl. Airport (RSW) to Buffalo Niagara Intl. Airport (BUF)?
Southwest Florida Intl. Airport (RSW)’s first flight to Buffalo Niagara Intl. Airport (BUF) takes off at approximately 8:15AM UTC-5. With a total flight time of 2h 50m, you’ll arrive at around 11:05AM UTC-5.
How long does it take to fly from Southwest Florida Intl. Airport (RSW) to Buffalo Niagara Intl. Airport (BUF)?
The average flight time from RSW to BUF is 2 hours and 59 minutes, covering a total distance of 1,150 mi.
What is the best time to fly from Southwest Florida Intl. Airport (RSW) to Buffalo Niagara Intl. Airport (BUF)?
To avoid potential delays on the Southwest Florida Intl. Airport (RSW) to Buffalo Niagara Intl. Airport (BUF) route, aim to fly before 3 PM. Departures after this time have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
What airports do you fly into for Buffalo from Southwest Florida Intl. Airport (RSW)?
If you’re traveling on a direct flight from Southwest Florida Intl. Airport (RSW) to Buffalo, Buffalo Niagara Intl. Airport (BUF) is the only airport you can land at.
Is it cheaper to buy a plane ticket from Southwest Florida Intl. Airport (RSW) to Buffalo Niagara Intl. Airport (BUF) last-minute?
Last-minute bookings from RSW to BUF are usually more expensive. For the best prices, start searching for flights early. That said, if your travel plans are flexible, you may find a cheap fare right before your journey.
Is it cheaper to book a RSW to BUF flight and hotel package?
Compared with arranging flights and hotels separately, booking a RSW to BUF flight and hotel package with Expedia could result in significant savings. Better yet, having it all in one place will take the hassle out of travel planning. Simply secure your flights and choose from our wide range of stays, then personalize your trip with extras like car rentals and activities.
Can I cancel or change the date of my flight from Southwest Florida Intl. Airport (RSW) to Buffalo Niagara Intl. Airport (BUF)?
If you reserved your RSW to BUF flight in the last 24 hours, you may be able to cancel or modify it without fees. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for more information.

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*Available to One Key members.