$100 Cheap Flights from Rochester (ROC) to Knoxville (TYS)

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Find available prices by choosing your travel dates.

Cheap Flights from Rochester to Knoxville (ROC-TYS)

Prices were available within the past 7 days and start at $100 for one-way flights and $211 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Delta
Delta
Delta
Delta
United
American Airlines
United
United
Delta
Flights from Rochester (ROC) to Knoxville (TYS)
Origin airport
Greater Rochester Intl.
Destination airport
McGhee Tyson
Airlines serving
American Airlines, Delta, United
Roundtrip price
$210
Distance
607 mi

Rochester to Knoxville Flights

The cheapest times to fly from Rochester to Knoxville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Rochester to Knoxville are during the month of July. You can find some of the cheapest flights from Rochester to Knoxville with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Rochester to Knoxville

Sunday is one of the best days to book for cheap flights from Rochester to Knoxville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Rochester to Knoxville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Rochester to Knoxville in 2025. You can also book with separate airlines for your outbound and return journeys, from $100 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Rochester to Knoxville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Rochester to Knoxville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

Is it cheaper to buy a plane ticket from Greater Rochester Intl. Airport to Knoxville Airport last minute?
Being the spontaneous type is a fantastic way to travel, but it’s not necessarily the wisest way to grab a cheap airfare. Think about booking your ROC to Knoxville Airport trip in advance rather than leaving it till the last minute. Based on flight pricing and demand studies in 2022, we have found that the best time to book domestic flights is between 28 – 35 days ahead of the departure date, and international flights three to four months in advance. Save up that spontaneity for when you reach Knoxville Airport!
What airports do you fly into for Knoxville from Rochester?
McGhee Tyson Airport (TYS), Gatlinburg, TN (GKT-Gatlinburg - Pigeon Forge) and Morristown, TN (MOR-Moore-Murrell) are your options when traveling from Rochester to Knoxville. Around 12 mi south of the center of Knoxville, McGhee Tyson Airport (TYS) is the city’s principal hub. Keep in mind things such as flight schedules and the distance to your hotel before deciding on an airport. Ijams Nature Center and Women’s Basketball Hall of Fame are a couple of awesome attractions to put on your must-see list when you reach your destination.
Can I change the date of my flight from ROC to Knoxville Airport?
Plans don’t always work out, so Expedia is here to help make things easy. To start, find your Greater Rochester Intl. Airport to McGhee Tyson Airport (TYS) itinerary through the Expedia Trips portal and browse the fare rules and conditions about change fees or other charges. If you booked your fare in the last 24 hours, some carriers will let you cancel without charge and organize new flights. If you booked more than 24 hours ago, contact us via our Customer Service portal to run through your options.

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*Available to One Key members.