$100 Cheap Flights from Roanoke (ROA) to Milwaukee (MKE)

View $100 flight on Sun, Aug 31, 2025Opens in a new window

  • Plan, book, fly with confidence

  • trending down icon
    Be in the know
    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon
    Book smarter
    Save up to 30% on select hotels after you book a flight*
  • one key icon
    Earn twice
    Earn your airline miles on top of our OneKeyCash
    Learn about One Key
Find available prices by choosing your travel dates.

Cheap Flights from Roanoke to Milwaukee (ROA-MKE)

Prices were available within the past 7 days and start at $100 for one-way flights and $199 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sat, May 24 - Wed, May 28
ROA
Roanoke
MKE
Milwaukee
$199 Roundtrip, found 2 days ago
$199
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, May 24 from Roanoke to Milwaukee, returning Wed, May 28, priced at $199 found 2 days ago
American Airlines
Sat, May 24 - Wed, May 28
ROA
Roanoke
MKE
Milwaukee
$221 Roundtrip, found 2 days ago
$221
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, May 24 from Roanoke to Milwaukee, returning Wed, May 28, priced at $221 found 2 days ago
Delta
Fri, Jul 4 - Fri, Jul 11
ROA
Roanoke
MKE
Milwaukee
$223 Roundtrip, found 4 hours ago
$223
Roundtrip
found 4 hours ago
Select Delta flight, departing Fri, Jul 4 from Roanoke to Milwaukee, returning Fri, Jul 11, priced at $223 found 4 hours ago
Delta
Tue, Jul 8 - Mon, Jul 14
ROA
Roanoke
MKE
Milwaukee
$229 Roundtrip, found 3 hours ago
$229
Roundtrip
found 3 hours ago
Select Delta flight, departing Tue, Jul 8 from Roanoke to Milwaukee, returning Mon, Jul 14, priced at $229 found 3 hours ago
Delta
Tue, Jul 1 - Fri, Jul 4
ROA
Roanoke
MKE
Milwaukee
$233 Roundtrip, found 4 hours ago
$233
Roundtrip
found 4 hours ago
Select Delta flight, departing Tue, Jul 1 from Roanoke to Milwaukee, returning Fri, Jul 4, priced at $233 found 4 hours ago
American Airlines
Tue, May 13 - Sat, May 17
ROA
Roanoke
MKE
Milwaukee
$234 Roundtrip, found 3 days ago
$234
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, May 13 from Roanoke to Milwaukee, returning Sat, May 17, priced at $234 found 3 days ago
Delta
Sun, May 25 - Thu, May 29
ROA
Roanoke
MKE
Milwaukee
$237 Roundtrip, found 3 days ago
$237
Roundtrip
found 3 days ago
Select Delta flight, departing Sun, May 25 from Roanoke to Milwaukee, returning Thu, May 29, priced at $237 found 3 days ago
Delta
Fri, Jun 13 - Mon, Jun 16
ROA
Roanoke
MKE
Milwaukee
$239 Roundtrip, found 6 hours ago
$239
Roundtrip
found 6 hours ago
Select Delta flight, departing Fri, Jun 13 from Roanoke to Milwaukee, returning Mon, Jun 16, priced at $239 found 6 hours ago
Delta
Wed, May 7 - Sun, May 11
ROA
Roanoke
MKE
Milwaukee
$249 Roundtrip, found 2 hours ago
$249
Roundtrip
found 2 hours ago
Select Delta flight, departing Wed, May 7 from Roanoke to Milwaukee, returning Sun, May 11, priced at $249 found 2 hours ago
United
Mon, Jun 30 - Sat, Jul 19
ROA
Roanoke
MKE
Milwaukee
$299 Roundtrip, found 1 day ago
$299
Roundtrip
found 1 day ago
Select United flight, departing Mon, Jun 30 from Roanoke to Milwaukee, returning Sat, Jul 19, priced at $299 found 1 day ago

Frequently asked questions

How much does a flight from Roanoke Regional Airport (ROA) to General Mitchell Intl. Airport (MKE) cost?
Discover the latest flight deals from ROA to MKE by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from ROA to MKE?
The cheapest flights from ROA to MKE are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from ROA to MKE?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from ROA to MKE. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Roanoke Regional Airport (ROA) to General Mitchell Intl. Airport (MKE)?
Nonstop flights from Roanoke Regional Airport (ROA) to General Mitchell Intl. Airport (MKE) aren’t available daily, so you’ll have to take a flight with a layover. Explore your options with Expedia’s filter tool. Enter your travel dates and click on either “1 Stop” or “2+ Stops.”
What day of the week has the most flights from ROA to MKE?
Typically you’ll have the most choice when it comes to flights on a Friday. Tuesdays tend to be the quietest.* However, this can change based on the airline, season and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Roanoke Regional Airport (ROA) to General Mitchell Intl. Airport (MKE)?
Book a flight from Roanoke Regional Airport (ROA) to General Mitchell Intl. Airport (MKE) that leaves before 3 PM to reduce the risk of cancellations and delays. Departures later than this are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Roanoke Regional Airport (ROA) to General Mitchell Intl. Airport (MKE) last-minute?
Holding off until just before your trip to book a flight from ROA to MKE generally means paying more. Although you may find some last-minute offers, there’s no guarantee. Allow some flexibility in your schedule to boost your chances of scoring a bargain.
Is it cheaper to book a ROA to MKE flight and hotel package?
Compared with arranging hotels and flights separately, booking a ROA to MKE flight and hotel package with Expedia could result in significant savings. Better yet, having it all in one place will take the hassle out of travel planning. Just secure your flights and choose from our extensive range of stays, then customize your trip with other add-ons like car rentals and activities.
Can I cancel or change the date of my flight from Roanoke Regional Airport (ROA) to General Mitchell Intl. Airport (MKE)?
Typically, you’re able to reschedule or cancel your ROA to MKE flight. However, additional fees may apply, especially if your booking was made more than 24 hours ago. Check your itinerary for the airline’s fees and rules on flight changes, or if you’d like more information, visit our Customer Service portal.
*Available to One Key members.