$150 Cheap Flights from Reno (RNO) to Des Moines (DSM)

View $150 flight on Wed, Aug 20, 2025Opens in a new window

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Find available prices by choosing your travel dates.

Cheap Flights from Reno to Des Moines (RNO-DSM)

Prices were available within the past 7 days and start at $150 for one-way flights and $299 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Southwest Airlines
Wed, Aug 20 - Wed, Aug 27
RNO
Reno
DSM
Des Moines
$299 Roundtrip, found 1 hour ago
$299
Roundtrip
found 1 hour ago
Select Southwest Airlines flight, departing Wed, Aug 20 from Reno to Des Moines, returning Wed, Aug 27, priced at $299 found 1 hour ago
American Airlines
Wed, Aug 20 - Wed, Aug 27
RNO
Reno
DSM
Des Moines
$299 Roundtrip, found 1 hour ago
$299
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Wed, Aug 20 from Reno to Des Moines, returning Wed, Aug 27, priced at $299 found 1 hour ago
Delta
Wed, Aug 20 - Wed, Aug 27
RNO
Reno
DSM
Des Moines
$299 Roundtrip, found 1 hour ago
$299
Roundtrip
found 1 hour ago
Select Delta flight, departing Wed, Aug 20 from Reno to Des Moines, returning Wed, Aug 27, priced at $299 found 1 hour ago
United
Wed, Aug 20 - Wed, Aug 27
RNO
Reno
DSM
Des Moines
$299 Roundtrip, found 1 hour ago
$299
Roundtrip
found 1 hour ago
Select United flight, departing Wed, Aug 20 from Reno to Des Moines, returning Wed, Aug 27, priced at $299 found 1 hour ago
Southwest Airlines
Wed, Aug 20 - Wed, Aug 27
RNO
Reno
DSM
Des Moines
$299 Roundtrip, found 1 hour ago
$299
Roundtrip
found 1 hour ago
Select Southwest Airlines flight, departing Wed, Aug 20 from Reno to Des Moines, returning Wed, Aug 27, priced at $299 found 1 hour ago
American Airlines
Wed, Aug 20 - Wed, Aug 27
RNO
Reno
DSM
Des Moines
$303 Roundtrip, found 1 hour ago
$303
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Wed, Aug 20 from Reno to Des Moines, returning Wed, Aug 27, priced at $303 found 1 hour ago
United
Wed, Aug 20 - Wed, Aug 27
RNO
Reno
DSM
Des Moines
$304 Roundtrip, found 1 hour ago
$304
Roundtrip
found 1 hour ago
Select United flight, departing Wed, Aug 20 from Reno to Des Moines, returning Wed, Aug 27, priced at $304 found 1 hour ago
United
Wed, Aug 20 - Wed, Aug 27
RNO
Reno
DSM
Des Moines
$309 Roundtrip, found 1 hour ago
$309
Roundtrip
found 1 hour ago
Select United flight, departing Wed, Aug 20 from Reno to Des Moines, returning Wed, Aug 27, priced at $309 found 1 hour ago
Delta
Sun, May 11 - Sat, May 24
RNO
Reno
DSM
Des Moines
$309 Roundtrip, found 6 days ago
$309
Roundtrip
found 6 days ago
Select Delta flight, departing Sun, May 11 from Reno to Des Moines, returning Sat, May 24, priced at $309 found 6 days ago
Alaska Airlines
Wed, May 28 - Sat, May 31
RNO
Reno
DSM
Des Moines
$439 Roundtrip, found 5 days ago
$439
Roundtrip
found 5 days ago
Select Alaska Airlines flight, departing Wed, May 28 from Reno to Des Moines, returning Sat, May 31, priced at $439 found 5 days ago
Flights from Reno (RNO) to Des Moines (DSM)
Origin airport
Reno-Tahoe Intl.
Destination airport
Des Moines Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$298
Distance
1374 mi

Reno to Des Moines Flights

The cheapest times to fly from Reno to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Reno to Des Moines are during the month of August. You can find some of the cheapest flights from Reno to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Reno to Des Moines

Sunday is one of the best days to book for cheap flights from Reno to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Reno to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Reno to Des Moines in 2025. You can also book with separate airlines for your outbound and return journeys, from $150 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Reno to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Reno to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Reno-Tahoe Intl. Airport (RNO) to Des Moines Intl. Airport (DSM) cost?
Discover the latest flight deals from RNO to DSM by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from RNO to DSM?
The cheapest flights from RNO to DSM are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from RNO to DSM?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from RNO to DSM. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Reno-Tahoe Intl. Airport (RNO) to Des Moines Intl. Airport (DSM)?
There are no daily nonstop flights departing from Reno-Tahoe Intl. Airport (RNO) to Des Moines Intl. Airport (DSM). But you can choose flights with layovers. Filter your search on Expedia to include one or more stops, and you’ll be cruising above the clouds before you know it.
What day of the week has the most flights from RNO to DSM?
Friday is usually the busiest day for flights, while Tuesday is often the quietest.* Remember that flight schedules can change depending on various factors, such as the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Reno-Tahoe Intl. Airport (RNO) to Des Moines Intl. Airport (DSM)?
To touch down at Des Moines Intl. Airport (DSM) on schedule, opt for a flight that leaves Reno-Tahoe Intl. Airport (RNO) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Reno-Tahoe Intl. Airport (RNO) to Des Moines Intl. Airport (DSM) last-minute?
Waiting until just before your departure to book a ticket from RNO to DSM generally means paying more. While it’s possible to find some last-minute discounts, they’re not always guaranteed. Keep your travel plans flexible for a better chance of getting a bargain.
Is it cheaper to book a RNO to DSM flight and hotel package?
Opting for a RNO to DSM flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip in one place. Choose from our wide range of accommodations and then add activities, flights and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Reno-Tahoe Intl. Airport (RNO) to Des Moines Intl. Airport (DSM)?
In most cases, you can cancel or modify your RNO to DSM flight. However, additional charges may apply, especially if you made your booking more than 24 hours ago. Check your itinerary for the airline’s rules and fees on flight changes, or if you’d like further information, visit our Customer Service portal.

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*Available to One Key members.