
Featured airlines
- Plan, book, fly with confidence
- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 30% on select hotels after you book a flight*
Cheap Flights from Portland to Santa Cruz (PWM-VVI)
Prices were available within the past 7 days and start at $309 for one-way flights and $683 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.










Origin airport | Portland Intl. Jetport |
Destination airport | Viru Viru Intl. |
Roundtrip price | $682 |
Distance | 4259 mi |
Portland to Santa Cruz Flights
The cheapest times to fly from Portland to Santa Cruz
On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Portland to Santa Cruz are during the month of May. You can find some of the cheapest flights from Portland to Santa Cruz with Expedia's search tool and vast selection of airlines.
The best time to book a flight from Portland to Santa Cruz
Sunday is one of the best days to book for cheap flights from Portland to Santa Cruz: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.
How to find cheap round-trip tickets from Portland to Santa Cruz
Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Portland to Santa Cruz in 2025. You can also book with separate airlines for your outbound and return journeys, from $309 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.
Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Portland to Santa Cruz flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.
You could also save big by booking one of Expedia's vacation packages. Bundling together your Portland to Santa Cruz airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.
*Terms apply.
Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.
Frequently asked questions
Explore a world of travel with Expedia
Flights
- Flights to Colcha K
- Flights to Uyuni
- Flights to Tiahuanaco
- Flights to Tupiza
- Flights to Copacabana
- Flights to Samaipata
- Flights to Villa Tunari
- Flights to Isla del Sol
- Flights to Rurrenabaque
- Flights to La Paz
- Flights to Warnes
- Flights to Tarija
- Flights to Oruro
- Flights to Santa Cruz
- Flights to Colchani
- Flights to Sucre
- Flights to Potosi
- Flights to Trinidad
- Flights to Cochabamba
- Flights to Coroico
- Flights from Portsmouth Intl.
- Flights from Concord Municipal
- Flights from Augusta State
- Flights from Sanford Seacoast Regional
- Flights from Auburn - Lewiston Municipal
- Flights from Knox County Regional
- Flights from Wiscasset
- Flights from Eastern Slopes Regional
- Flights from Laconia Municipal
- Flights from Robert Lafleur
- American Airlines Portland (PWM) to Charleston (CHS) flights
- Delta Portland (PWM) to Denver (DEN) flights
- United Portland (PWM) to Newark Liberty Intl. Airport (EWR) flights
- United Portland (PWM) to Phoenix (PHX) flights
- American Airlines Portland (PWM) to Washington (DCA) flights
- avianca New York (JFK) to Santa Cruz (VVI) flights
- avianca Washington (IAD) to Santa Cruz (VVI) flights
- avianca Miami (MIA) to Santa Cruz (VVI) flights
- Copa Phoenix (PHX) to Santa Cruz (VVI) flights
- United Boston (BOS) to Santa Cruz (VVI) flights
- Delta Portland (PWM) to Charlotte (CLT) flights
- Delta Portland (PWM) to New York (JFK) flights
- Delta Portland (PWM) to New York (LGA) flights
- United Portland (PWM) to Tampa (TPA) flights
- American Airlines Portland (PWM) to Fort Lauderdale (FLL) flights
- Austrian Airlines
- United
- Frontier Airlines
- Scandinavian Airlines
- Aeromexico
- JetBlue Airways
- American Airlines
- Breeze Airways
- Alaska Airlines
- Air Canada
- Delta
- LATAM Airlines Group
- KLM
- WestJet
- Qatar Airways
- Copa
- Flights from Portland (PWM) to Miami (MIA)
- Flights from Sanford (SFM) to Miami (MIA)
- Flights from Bangor (BGR) to Atlanta (ATL)
- Flights from Portland (PWM) to Charleston (CHS)
- Flights from Bangor (BGR) to Chicago (ORD)
- Flights from Portland (PWM) to Denver (DEN)
- Flights from Bangor (BGR) to Philadelphia (PHL)
- Flights from Washington (DCA) to Bangor (BGR)
- Flights from Charlotte (CLT) to Bangor (BGR)
- Flights from Detroit (DTW) to Bangor (BGR)
- Flights from Nashville (BNA) to Bangor (BGR)
- Flights from Philadelphia (PHL) to Bangor (BGR)
- Flights from Dallas (DFW) to Bangor (BGR)
- Flights from Newark Liberty Intl. Airport (EWR) to Bangor (BGR)
- Flights from Boston (BOS) to Bangor (BGR)
- Flights from Atlanta (ATL) to Bangor (BGR)
- Flights from Baltimore (BWI) to Bangor (BGR)
- Flights from Raleigh (RDU) to Bangor (BGR)
- Flights from Los Angeles (LAX) to Bangor (BGR)
- Flights from Tampa (TPA) to Bangor (BGR)
- Flights from Portland (PWM) to Newark Liberty Intl. Airport (EWR)
- Flights from Bangor (BGR) to Honolulu (HNL)
- Flights from Bangor (BGR) to Las Vegas (LAS)
- Flights from Bangor (BGR) to Nashville (BNA)
- Flights from Portland (PWM) to Phoenix (PHX)
- Flights from Bangor (BGR) to Phoenix (PHX)
- Flights from Bangor (BGR) to Seattle (SEA)
- Flights from New York (JFK) to Bar Harbor (BHB)
- Flights from Philadelphia (PHL) to Bar Harbor (BHB)
- Flights from Bangor (BGR) to Washington (DCA)
- Flights from Portland (PWM) to Washington (DCA)
- Flights from Bangor (BGR) to Orlando (MCO)
- Flights from New York (LGA) to Santa Cruz (VVI)
- Flights from Denver (DEN) to Santa Cruz (VVI)
- Flights from Newark Liberty Intl. Airport (EWR) to Santa Cruz (VVI)
- Flights from Miami (MIA) to Santa Cruz (VVI)
- Flights from Chicago (ORD) to Santa Cruz (VVI)
- Flights from Boston (BOS) to Santa Cruz (VVI)
- Flights from Los Angeles (LAX) to Santa Cruz (VVI)
- Flights from Fort Lauderdale (FLL) to Santa Cruz (VVI)
- Flights from Washington (DCA) to Santa Cruz (VVI)
- Flights from São Paulo (GRU) to Santa Cruz (VVI)
- Flights from Phoenix (PHX) to Santa Cruz (VVI)
- Flights from Managua (MGA) to Santa Cruz (VVI)
- Flights from Bangor (BGR) to Boston (BOS)
- Flights from Portland (PWM) to Charlotte (CLT)
- Flights from Portland (PWM) to New York (JFK)
- Flights from Portland (PWM) to Houston (IAH)
- Flights from Portland (PWM) to New York (LGA)
- Flights from Bangor (BGR) to Fort Myers (RSW)
- Flights from Portland (PWM) to Tampa (TPA)
- Flights from Bangor (BGR) to Tampa (TPA)
- Flights from Portland (PWM) to Fort Lauderdale (FLL)
- Flights from Bangor (BGR) to Fort Lauderdale (FLL)