$94 Cheap Flights from Portland (PWM) to St. Louis (STL)

View $94 flight on Sat, May 24, 2025Opens in a new window

Popular airlines from Portland Intl. Jetport Airport (PWM) to St. Louis Lambert Intl. Airport (STL)

  • Plan, book, fly with confidence

  • trending down icon
    Be in the know
    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon
    Book smarter
    Save up to 30% on select hotels after you book a flight*
  • one key icon
    Earn twice
    Earn your airline miles on top of our OneKeyCash
    Learn about One Key
Find available prices by choosing your travel dates.

Cheap Flights from Portland to St. Louis (PWM-STL)

Prices were available within the past 7 days and start at $94 for one-way flights and $188 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Sat, Apr 26 - Wed, Apr 30
PWM
Portland
STL
St. Louis
$188 Roundtrip, found 8 hours ago
$188
Roundtrip
found 8 hours ago
Select Frontier Airlines flight, departing Sat, Apr 26 from Portland to St. Louis, returning Wed, Apr 30, priced at $188 found 8 hours ago
Frontier Airlines
Sat, Apr 26 - Sat, May 10
PWM
Portland
STL
St. Louis
$208 Roundtrip, just found
$208
Roundtrip
just found
Select Frontier Airlines flight, departing Sat, Apr 26 from Portland to St. Louis, returning Sat, May 10, priced at $208 just found
Frontier Airlines
Thu, May 1 - Fri, May 9
PWM
Portland
STL
St. Louis
$228 Roundtrip, just found
$228
Roundtrip
just found
Select Frontier Airlines flight, departing Thu, May 1 from Portland to St. Louis, returning Fri, May 9, priced at $228 just found
Frontier Airlines
Sat, May 31 - Fri, Jun 6
PWM
Portland
STL
St. Louis
$238 Roundtrip, found 3 hours ago
$238
Roundtrip
found 3 hours ago
Select Frontier Airlines flight, departing Sat, May 31 from Portland to St. Louis, returning Fri, Jun 6, priced at $238 found 3 hours ago
Frontier Airlines
Fri, May 2 - Sun, May 11
PWM
Portland
STL
St. Louis
$248 Roundtrip, just found
$248
Roundtrip
just found
Select Frontier Airlines flight, departing Fri, May 2 from Portland to St. Louis, returning Sun, May 11, priced at $248 just found
Frontier Airlines
Sat, Apr 26 - Sun, May 4
PWM
Portland
STL
St. Louis
$270 Roundtrip, just found
$270
Roundtrip
just found
Select Frontier Airlines flight, departing Sat, Apr 26 from Portland to St. Louis, returning Sun, May 4, priced at $270 just found
American Airlines
Wed, May 28 - Wed, Jun 4
PWM
Portland
STL
St. Louis
$272 Roundtrip, found 2 hours ago
$272
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Wed, May 28 from Portland to St. Louis, returning Wed, Jun 4, priced at $272 found 2 hours ago
Delta
Wed, May 28 - Wed, Jun 4
PWM
Portland
STL
St. Louis
$285 Roundtrip, found 2 hours ago
$285
Roundtrip
found 2 hours ago
Select Delta flight, departing Wed, May 28 from Portland to St. Louis, returning Wed, Jun 4, priced at $285 found 2 hours ago
United
Tue, May 20 - Wed, May 28
PWM
Portland
STL
St. Louis
$285 Roundtrip, found 1 day ago
$285
Roundtrip
found 1 day ago
Select United flight, departing Tue, May 20 from Portland to St. Louis, returning Wed, May 28, priced at $285 found 1 day ago
Southwest Airlines
Wed, May 28 - Wed, Jun 4
PWM
Portland
STL
St. Louis
$290 Roundtrip, found 2 hours ago
$290
Roundtrip
found 2 hours ago
Select Southwest Airlines flight, departing Wed, May 28 from Portland to St. Louis, returning Wed, Jun 4, priced at $290 found 2 hours ago

Frequently asked questions

How much does a flight from Portland Intl. Jetport Airport (PWM) to Lambert-St. Louis Intl. Airport (STL) cost?
Discover the latest flight deals from PWM to STL by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from PWM to STL?
The cheapest flights from PWM to STL are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from PWM to STL?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from PWM to STL. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Portland Intl. Jetport Airport (PWM) to Lambert-St. Louis Intl. Airport (STL)?
You’ll have to take a flight with a layover if you’re traveling from Portland Intl. Jetport Airport (PWM) to Lambert-St. Louis Intl. Airport (STL). Direct flights don’t operate daily on this route. However, just filter your search to include one or more stops to discover the best option for your trip.
What day of the week has the most flights from PWM to STL?
Friday is generally the busiest day for flights, while Tuesday tends to be the quietest.* Keep in mind that flight schedules can vary based on various factors, including the time of year and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Portland Intl. Jetport Airport (PWM) to Lambert-St. Louis Intl. Airport (STL)?
To avoid possible delays on the Portland Intl. Jetport Airport (PWM) to Lambert-St. Louis Intl. Airport (STL) route, aim to fly before 3 PM. Later departures have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Portland Intl. Jetport Airport (PWM) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Holding off until right before your break to book a flight from PWM to STL often results in higher prices. While you may come across some last-minute discounts, they aren’t always guaranteed. Be flexible with your itinerary for a better chance of snagging a bargain.
Is it cheaper to book a PWM to STL flight and hotel package?
Compared with arranging hotels and flights separately, booking a PWM to STL flight and hotel package with Expedia could result in significant savings. Better still, having everything in one place will take the hassle out of travel planning. Simply secure your flights and select from our wide range of hotels, then personalize your trip with other add-ons like tours, car rentals and activities.
Can I cancel or change the date of my flight from Portland Intl. Jetport Airport (PWM) to Lambert-St. Louis Intl. Airport (STL)?
In most instances, you can cancel or reschedule your PWM to STL flight. However, there may be additional charges, especially if you made your booking more than 24 hours ago. Check your itinerary for the airline’s fees and guidelines on flight changes, or if you’d like more information, go to our Customer Service portal.
*Available to One Key members.