$189 Cheap Flights from Panama City (PTY) to Santa Cruz (VVI)

View $189 flight on Fri, Jun 13, 2025Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to Santa Cruz (VVI-Viru Viru Intl.)

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Find available prices by choosing your travel dates.

Cheap Flights from Panama City to Santa Cruz (PTY-VVI)

Prices were available within the past 7 days and start at $189 for one-way flights and $365 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
Wed, Oct 1 - Wed, Oct 8
PTY
Panama City
VVI
Santa Cruz
$365 Roundtrip, found 7 hours ago
$365
Roundtrip
found 7 hours ago
Select avianca flight, departing Wed, Oct 1 from Panama City to Santa Cruz, returning Wed, Oct 8, priced at $365 found 7 hours ago
avianca
Fri, Jun 13 - Fri, Jun 20
PTY
Panama City
VVI
Santa Cruz
$393 Roundtrip, found 2 hours ago
$393
Roundtrip
found 2 hours ago
Select avianca flight, departing Fri, Jun 13 from Panama City to Santa Cruz, returning Fri, Jun 20, priced at $393 found 2 hours ago
avianca
Fri, May 23 - Mon, Jun 2
PTY
Panama City
VVI
Santa Cruz
$422 Roundtrip, found 2 days ago
$422
Roundtrip
found 2 days ago
Select avianca flight, departing Fri, May 23 from Panama City to Santa Cruz, returning Mon, Jun 2, priced at $422 found 2 days ago
avianca
Wed, Oct 1 - Wed, Oct 8
PTY
Panama City
VVI
Santa Cruz
$514 Roundtrip, found 7 hours ago
$514
Roundtrip
found 7 hours ago
Select avianca flight, departing Wed, Oct 1 from Panama City to Santa Cruz, returning Wed, Oct 8, priced at $514 found 7 hours ago
avianca
Tue, May 6 - Wed, May 14
PTY
Panama City
VVI
Santa Cruz
$530 Roundtrip, found 8 hours ago
$530
Roundtrip
found 8 hours ago
Select avianca flight, departing Tue, May 6 from Panama City to Santa Cruz, returning Wed, May 14, priced at $530 found 8 hours ago
avianca
Fri, Jun 13 - Fri, Jun 20
PTY
Panama City
VVI
Santa Cruz
$543 Roundtrip, found 2 hours ago
$543
Roundtrip
found 2 hours ago
Select avianca flight, departing Fri, Jun 13 from Panama City to Santa Cruz, returning Fri, Jun 20, priced at $543 found 2 hours ago
Copa
Tue, Nov 18 - Tue, Dec 2
PTY
Panama City
VVI
Santa Cruz
$544 Roundtrip, found 1 day ago
$544
Roundtrip
found 1 day ago
Select Copa flight, departing Tue, Nov 18 from Panama City to Santa Cruz, returning Tue, Dec 2, priced at $544 found 1 day ago
avianca
Tue, Jun 3 - Thu, Jun 5
PTY
Panama City
VVI
Santa Cruz
$559 Roundtrip, found 1 day ago
$559
Roundtrip
found 1 day ago
Select avianca flight, departing Tue, Jun 3 from Panama City to Santa Cruz, returning Thu, Jun 5, priced at $559 found 1 day ago
avianca
Fri, May 23 - Mon, Jun 2
PTY
Panama City
VVI
Santa Cruz
$572 Roundtrip, found 2 days ago
$572
Roundtrip
found 2 days ago
Select avianca flight, departing Fri, May 23 from Panama City to Santa Cruz, returning Mon, Jun 2, priced at $572 found 2 days ago
avianca
Fri, Jun 13 - Fri, Jun 20
PTY
Panama City
VVI
Santa Cruz
$593 Roundtrip, found 2 hours ago
$593
Roundtrip
found 2 hours ago
Select avianca flight, departing Fri, Jun 13 from Panama City to Santa Cruz, returning Fri, Jun 20, priced at $593 found 2 hours ago

Frequently asked questions

How much does a flight from Tocumen Intl. Airport (PTY) to Viru Viru Intl. Airport (VVI) cost?
You can find cheap return tickets from Tocumen Intl. Airport (PTY) to Viru Viru Intl. Airport (VVI) starting from $697. Book a seat and get ready for takeoff. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Copa flight leaving PTY on April 29 2025 and touching down at VVI. The price was last updated on April 24 2025 and has not changed since.
What is the cheapest month to fly from PTY to VVI?
The cheapest flights from PTY to VVI are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Tocumen Intl. Airport (PTY) to Viru Viru Intl. Airport (VVI)?
Jump on a direct flight with Copa Airlines and head straight from Tocumen Intl. Airport (PTY) to Viru Viru Intl. Airport (VVI).
What is the cheapest airline that flies from PTY to VVI?
Fly from PTY to VVI with Copa. This carrier currently offers the cheapest one-way ticket for this route, starting from $673. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from PTY on April 25 2025. Prices were last updated on April 24 2025 and have not changed since.
How many flights per day from Tocumen Intl. Airport (PTY) to Viru Viru Intl. Airport (VVI)?
On average, Tocumen Intl. Airport (PTY) only offers 1 direct flight to Viru Viru Intl. Airport (VVI) per day. For additional options, try our easy-to-use filters. Just enter your dates, then choose “1 Stop” or “2+ Stops” to discover flights with layovers.
What are the most popular departure times for flights from Tocumen Intl. Airport (PTY) to Viru Viru Intl. Airport (VVI)?
The 4 PM departures from PTY to VVI are the top choice for many travelers. They can also be more expensive. If you want to save on your fare, pick a less crowded time to fly.
What day of the week has the most flights from PTY to VVI?
Friday offers the most flights from Tocumen Intl. Airport (PTY) to Viru Viru Intl. Airport (VVI). Consider traveling on this day and you’ll have a greater chance of finding a departure that fits your schedule.
What is the earliest flight from Tocumen Intl. Airport (PTY) to Viru Viru Intl. Airport (VVI)?
Take the earliest flight at around 4:04PM UTC-5, leaving from Tocumen Intl. Airport (PTY). You’ll be flying for approximately 5h, coming in to land at Viru Viru Intl. Airport (VVI) at approximately 10:04PM UTC-4.
How long does it take to fly from Tocumen Intl. Airport (PTY) to Viru Viru Intl. Airport (VVI)?
It usually takes 5 hours to travel the 2,200 mi from PTY to VVI.
What is the best time to fly from Tocumen Intl. Airport (PTY) to Viru Viru Intl. Airport (VVI)?
Book a flight from Tocumen Intl. Airport (PTY) to Viru Viru Intl. Airport (VVI) that takes off before 3 PM to reduce the likelihood of delays. Later departures have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
What airports do you fly into for Santa Cruz from Tocumen Intl. Airport (PTY)?
Check out your flight options from Tocumen Intl. Airport (PTY) to Viru Viru Intl. Airport (VVI). This is the only airport in Santa Cruz you can jet into if you’re taking a direct flight.
Is it cheaper to buy a plane ticket from Tocumen Intl. Airport (PTY) to Viru Viru Intl. Airport (VVI) last-minute?
Booking your flight from PTY to VVI shortly before your journey is usually more expensive. However, if there’s some wiggle room with your departure times and dates, you could bag a cheap last-minute fare.
Is it cheaper to book a PTY to VVI flight and hotel package?
Compared with arranging hotels and flights separately, booking a PTY to VVI flight and hotel package with Expedia could result in significant savings. What’s more, having everything in one convenient place will take the stress out of planning your trip. Simply pick your flights and choose from our extensive range of hotels, then personalize your trip with extras like tours and car rentals.
Can I cancel or change the date of my flight from Tocumen Intl. Airport (PTY) to Viru Viru Intl. Airport (VVI)?
If you reserved your PTY to VVI flight within the last 24 hours, you may be able to cancel or modify it without fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for more details.
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