$364 Cheap Flights from Panama City (PTY) to Houston (IAH)

Popular airlines from Tocumen Intl. Airport (PTY) to George Bush Intercontinental Airport (IAH)

Find available prices by choosing your travel dates.

Cheap Flights from Panama City to Houston (PTY-IAH)

Prices were available within the past 7 days and start at $364 for one-way flights and $613 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

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United
American Airlines
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Aeromexico
Flights from Panama City (PTY) to Houston (IAH)
Origin airport
Tocumen Intl.
Destination airport
George Bush Intercontinental
Airlines serving
Aeromexico, American Airlines, Delta, United, avianca
Roundtrip price
$612
Distance
1775 mi

Panama City to Houston Flights

The cheapest times to fly from Panama City to Houston

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Houston are during the month of May. You can find some of the cheapest flights from Panama City to Houston with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Panama City to Houston

Sunday is one of the best days to book for cheap flights from Panama City to Houston: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Panama City to Houston

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Houston in 2025. You can also book with separate airlines for your outbound and return journeys, from $364 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Houston flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Houston airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Tocumen Intl. Airport (PTY) to George Bush Intercontinental Airport (IAH) cost?
You can score cheap return fares from Tocumen Intl. Airport (PTY) to George Bush Intercontinental Airport (IAH) starting from $782. Grab your seat and get ready to go. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a United flight leaving PTY on May 15 2025 and touching down at IAH. The price was last updated on April 24 2025 and has not changed since.
What is the cheapest month to fly from PTY to IAH?
The cheapest flights from PTY to IAH are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Tocumen Intl. Airport (PTY) to George Bush Intercontinental Airport (IAH)?
Catch a direct flight with United Airlines and journey straight from Tocumen Intl. Airport (PTY) to George Bush Intercontinental Airport (IAH).
What is the cheapest airline that flies from PTY to IAH?
Currently, the cheapest airline operating one-way flights from PTY to IAH is United. You can take off on this route from $737. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from PTY on June 2 2025. Prices were last updated on April 24 2025 and have not changed since.
How many flights per day from Tocumen Intl. Airport (PTY) to George Bush Intercontinental Airport (IAH)?
When taking off from Tocumen Intl. Airport (PTY), you can choose from an average of 3 daily nonstop flights to George Bush Intercontinental Airport (IAH).
What are the most popular departure times for flights from Tocumen Intl. Airport (PTY) to George Bush Intercontinental Airport (IAH)?
Flights between PTY and IAH are their busiest at 8 AM. If you’re after a more relaxed experience and potentially cheaper fares, look for a time outside the usual busy windows.
What day of the week has the most flights from PTY to IAH?
If you fly on a Friday, you’ll get the biggest range of choices for flights from Tocumen Intl. Airport (PTY) to George Bush Intercontinental Airport (IAH).
What is the earliest flight from Tocumen Intl. Airport (PTY) to George Bush Intercontinental Airport (IAH)?
The first flight of the day out of Tocumen Intl. Airport (PTY) is at around 8:55AM UTC-5. Board this plane and you’ll reach George Bush Intercontinental Airport (IAH) at approximately 12:19PM UTC-6. The total travel time is 4h 24m.
How long does it take to fly from Tocumen Intl. Airport (PTY) to George Bush Intercontinental Airport (IAH)?
The average flight time from PTY to IAH is 4 hours and 24 minutes, covering a distance of 1,800 mi.
What airline has the least delays from PTY to IAH?
Consider traveling with Copa Airlines if you’d like to go straight from Tocumen Intl. Airport (PTY) to George Bush Intercontinental Airport (IAH) without any delays. This carrier has the strongest track record for punctuality, with an on-time score of 85%. Want real-time updates? You can keep an eye on your flight status using the Expedia App.
What is the best time to fly from Tocumen Intl. Airport (PTY) to George Bush Intercontinental Airport (IAH)?
Book a flight from Tocumen Intl. Airport (PTY) to George Bush Intercontinental Airport (IAH) that leaves before 3 PM to reduce the risk of cancellations and delays. Departures after this time have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
What airports do you fly into for Houston from Tocumen Intl. Airport (PTY)?
If you’re traveling on a direct flight from Tocumen Intl. Airport (PTY) to Houston, George Bush Intercontinental Airport (IAH) is the only airport you can touch down at.
Is it cheaper to buy a plane ticket from Tocumen Intl. Airport (PTY) to George Bush Intercontinental Airport (IAH) last-minute?
Booking your ticket from PTY to IAH shortly before your getaway is generally more expensive. However, if there’s some wiggle room with your departure dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a PTY to IAH flight and hotel package?
Securing a PTY to IAH flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels in one place. Choose from our wide range of stays and then add activities, car rentals and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Tocumen Intl. Airport (PTY) to George Bush Intercontinental Airport (IAH)?
Typically, you can modify or cancel your PTY to IAH flight. However, there may be additional fees, especially if your booking was made over 24 hours ago. Double-check your itinerary for the airline’s guidelines and fees on flight changes, or if you’d like further details, head to our Customer Service portal.

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*Available to One Key members.