
Featured airlines
- Plan, book, fly with confidence
- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 30% on select hotels after you book a flight*
Cheap Flights from Panama City to Guatemala City (PTY-GUA)
Prices were available within the past 7 days and start at $107 for one-way flights and $195 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.










Origin airport | Tocumen Intl. |
Destination airport | La Aurora Intl. |
Airlines serving | Aeromexico, Copa, avianca |
Roundtrip price | $194 |
Distance | 844 mi |
Panama City to Guatemala City Flights
The cheapest times to fly from Panama City to Guatemala City
On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Guatemala City are during the month of May. You can find some of the cheapest flights from Panama City to Guatemala City with Expedia's search tool and vast selection of airlines.
The best time to book a flight from Panama City to Guatemala City
Sunday is one of the best days to book for cheap flights from Panama City to Guatemala City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.
How to find cheap round-trip tickets from Panama City to Guatemala City
Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Guatemala City in 2025. You can also book with separate airlines for your outbound and return journeys, from $107 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.
Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Guatemala City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.
You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Guatemala City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.
*Terms apply.
Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.
Frequently asked questions
Explore a world of travel with Expedia
Lodging
- Best Western Plus Hotel Stofella
- AC Hotel by Marriott Guatemala City
- Hyatt Centric Guatemala City
- Barceló Guatemala City
- Meraki Boutique Hotel
- Holiday Inn Guatemala City by IHG
- Aurora Express
- Real InterContinental Guatemala by IHG
- Tikal Futura Hotel & Convention Center
- The Westin Camino Real, Guatemala
- Wyndham Garden Guatemala City
- Hotel Fontabella
- Suites Terraza Imperial
- In & Out Hotel
- Hotels near Zona 10
- Hotels near Paseo Cayala
- Hotels near U.S. Embassy in Guatemala
Flights
- Air France
- American Airlines
- Air Europa
- Turkish Airlines
- EVA Airways
- Asiana Airlines
- avianca
- Delta
- Emirates
- KLM
- Etihad Airways
- Qatar Airways
- Iberia
- Copa
- British Airways
- United
- Flights to Antigua Guatemala
- Flights to San Marcos La Laguna
- Flights to San Pedro La Laguna
- Flights to Esquipulas
- Flights to Flores
- Flights to Quetzaltenango
- Flights to Santiago Atitlán
- Flights to Taxisco
- Flights to Cobán
- Flights to Puerto Barrios
- Flights to San Juan La Laguna
- Flights to Puerto San Jose
- Flights to Santa Cruz La Laguna
- Flights to Santa Catarina Palopo
- Flights to Guatemala City
- Flights to Sololá
- Flights to El Paredon
- Flights to Livingston
- Flights to Retalhuleu
- Flights to Panajachel
- Flights from Scarlett Martinez Intl.
- Flights from Bocas del Toro Intl.
- Flights from Marcos A. Gelabert Intl.
- Flights from Contadora Island
- Flights from Alonso Valderrama
- Flights from Panama Pacifico Intl.
- avianca New York (JFK) to Guatemala City (GUA) flights
- avianca Washington (IAD) to Guatemala City (GUA) flights
- American Airlines Boston (BOS) to Guatemala City (GUA) flights
- American Airlines Miami (MIA) to Guatemala City (GUA) flights
- Copa Panama City (PTY) to Managua (MGA) flights
- United Panama City (PTY) to Newark Liberty Intl. Airport (EWR) flights
- Flights from Miami (MIA) to Guatemala City (GUA)
- Flights from Orange County (SNA) to Guatemala City (GUA)
- Flights from New York (JFK) to Guatemala City (GUA)
- Flights from Fort Lauderdale (FLL) to Guatemala City (GUA)
- Flights from Chicago (ORD) to Guatemala City (GUA)
- Flights from Washington (DCA) to Guatemala City (GUA)
- Flights from Washington (IAD) to Guatemala City (GUA)
- Flights from Newark Liberty Intl. Airport (EWR) to Guatemala City (GUA)
- Flights from Los Angeles (LAX) to Guatemala City (GUA)
- Flights from New York (LGA) to Guatemala City (GUA)
- Flights from Boston (BOS) to Guatemala City (GUA)
- Flights from Seattle (SEA) to Guatemala City (GUA)
- Flights from Panama City (PTY) to Rio de Janeiro (GIG)
- Flights from Panama City (PTY) to Managua (MGA)
- Flights from Panama City (PTY) to Miami (MIA)
- Flights from Panama City (PAC) to David (DAV)
- Flights from Panama City (PAC) to Bocas del Toro (BOC)
- Flights from Miami (MIA) to Panama City (PAC)
- Flights from Philadelphia (PHL) to Panama City (PAC)
- Flights from Bocas del Toro (BOC) to Panama City (PAC)
- Flights from Panama City (PTY) to Fort Lauderdale (FLL)
- Flights from Panama City (PTY) to New York (JFK)
- Flights from Panama City (PTY) to Contadora Island (OTD)
- Flights from Panama City (PTY) to Los Angeles (LAX)
- Flights from Panama City (PTY) to Newark Liberty Intl. Airport (EWR)
- Flights from Panama City (PTY) to Mumbai (BOM)
- Flights from Panama City (PTY) to Santo Domingo (SDQ)
- Flights from Panama City (PTY) to New York (LGA)
- Flights from Panama City (PTY) to Mexico City (MEX)
- Flights from Panama City (PTY) to Medellín (MDE)