$289 Cheap Flights from Panama City (PTY) to Charlotte (CLT)

View $289 flight on Mon, Jul 28, 2025Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to Charlotte-Douglas Intl. Airport (CLT)

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Find available prices by choosing your travel dates.

Cheap Flights from Panama City to Charlotte (PTY-CLT)

Prices were available within the past 7 days and start at $289 for one-way flights and $469 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Thu, Jul 24 - Sun, Jul 27
PTY
Panama City
CLT
Charlotte
$469 Roundtrip, found 8 hours ago
$469
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Thu, Jul 24 from Panama City to Charlotte, returning Sun, Jul 27, priced at $469 found 8 hours ago
United
Mon, Jul 14 - Tue, Jul 29
PTY
Panama City
CLT
Charlotte
$469 Roundtrip, found 8 hours ago
$469
Roundtrip
found 8 hours ago
Select United flight, departing Mon, Jul 14 from Panama City to Charlotte, returning Tue, Jul 29, priced at $469 found 8 hours ago
American Airlines
Mon, Sep 15 - Wed, Sep 24
PTY
Panama City
CLT
Charlotte
$473 Roundtrip, found 11 hours ago
$473
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Mon, Sep 15 from Panama City to Charlotte, returning Wed, Sep 24, priced at $473 found 11 hours ago
Delta
Thu, Jul 24 - Sun, Jul 27
PTY
Panama City
CLT
Charlotte
$475 Roundtrip, found 8 hours ago
$475
Roundtrip
found 8 hours ago
Select Delta flight, departing Thu, Jul 24 from Panama City to Charlotte, returning Sun, Jul 27, priced at $475 found 8 hours ago
United
Tue, Jul 1 - Tue, Jul 8
PTY
Panama City
CLT
Charlotte
$476 Roundtrip, found 16 hours ago
$476
Roundtrip
found 16 hours ago
Select United flight, departing Tue, Jul 1 from Panama City to Charlotte, returning Tue, Jul 8, priced at $476 found 16 hours ago
United
Tue, Jul 1 - Tue, Jul 8
PTY
Panama City
CLT
Charlotte
$478 Roundtrip, found 16 hours ago
$478
Roundtrip
found 16 hours ago
Select United flight, departing Tue, Jul 1 from Panama City to Charlotte, returning Tue, Jul 8, priced at $478 found 16 hours ago
American Airlines
Thu, Jul 24 - Sun, Jul 27
PTY
Panama City
CLT
Charlotte
$478 Roundtrip, found 8 hours ago
$478
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Thu, Jul 24 from Panama City to Charlotte, returning Sun, Jul 27, priced at $478 found 8 hours ago
American Airlines
Thu, Sep 25 - Tue, Sep 30
PTY
Panama City
CLT
Charlotte
$481 Roundtrip, found 1 day ago
$481
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Sep 25 from Panama City to Charlotte, returning Tue, Sep 30, priced at $481 found 1 day ago
Delta
Tue, Aug 5 - Sun, Aug 24
PTY
Panama City
CLT
Charlotte
$482 Roundtrip, found 8 hours ago
$482
Roundtrip
found 8 hours ago
Select Delta flight, departing Tue, Aug 5 from Panama City to Charlotte, returning Sun, Aug 24, priced at $482 found 8 hours ago
Copa
Tue, Jul 1 - Tue, Jul 8
PTY
Panama City
CLT
Charlotte
$1,286 Roundtrip, found 16 hours ago
$1,286
Roundtrip
found 16 hours ago
Select Copa flight, departing Tue, Jul 1 from Panama City to Charlotte, returning Tue, Jul 8, priced at $1,286 found 16 hours ago

Frequently asked questions

How much does a flight from Tocumen Intl. Airport (PTY) to Charlotte-Douglas Intl. Airport (CLT) cost?
Discover the latest flight deals from PTY to CLT by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from PTY to CLT?
The cheapest flights from PTY to CLT are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from PTY to CLT?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from PTY to CLT. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Tocumen Intl. Airport (PTY) to Charlotte-Douglas Intl. Airport (CLT)?
You’ll need to catch a flight with a layover when traveling from Tocumen Intl. Airport (PTY) to Charlotte-Douglas Intl. Airport (CLT). There are no daily direct flights on this route. However, just filter your search to include one or two stops to find an option that works for you.
What day of the week has the most flights from PTY to CLT?
You’ll typically find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Tocumen Intl. Airport (PTY) to Charlotte-Douglas Intl. Airport (CLT)?
Opt for a flight from Tocumen Intl. Airport (PTY) to Charlotte-Douglas Intl. Airport (CLT) that takes off before 3 PM to reduce the risk of delays and cancellations. Departures after this time are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Tocumen Intl. Airport (PTY) to Charlotte-Douglas Intl. Airport (CLT) last-minute?
Last-minute bookings from PTY to CLT are typically more expensive. For the lowest rates, start looking for flights ahead of time. That said, if you’re flexible with your travel plans, it’s possible to find a cheap ticket right before your journey.
Is it cheaper to book a PTY to CLT flight and hotel package?
You’ll generally save money by securing a PTY to CLT flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it’s easy to manage everything in one place. After selecting your preferred accommodations and flights, consider adding extras like activities, tours and car rentals.
Can I cancel or change the date of my flight from Tocumen Intl. Airport (PTY) to Charlotte-Douglas Intl. Airport (CLT)?
In most cases, you can cancel or reschedule your PTY to CLT flight. However, additional charges may apply, especially if your booking was made more than 24 hours ago. Check your itinerary for the airline’s fees and rules on flight changes, or if you want more details, head to our Customer Service portal.
*Available to One Key members.