$129 Cheap Flights from Pittsburgh (PIT) to Des Moines (DSM)

View $129 flight on Tue, Jun 10, 2025Opens in a new window

Popular airlines from Pittsburgh Intl. Airport (PIT) to Des Moines International Airport (DSM)

  • Plan, book, fly with confidence

  • trending down icon
    Be in the know
    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon
    Book smarter
    Save up to 30% on select hotels after you book a flight*
  • one key icon
    Earn twice
    Earn your airline miles on top of our OneKeyCash
    Learn about One Key
Find available prices by choosing your travel dates.

Cheap Flights from Pittsburgh to Des Moines (PIT-DSM)

Prices were available within the past 7 days and start at $129 for one-way flights and $257 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Southwest Airlines
Tue, Jun 10 - Wed, Jun 11
PIT
Pittsburgh
DSM
Des Moines
$257 Roundtrip, found 6 days ago
$257
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Tue, Jun 10 from Pittsburgh to Des Moines, returning Wed, Jun 11, priced at $257 found 6 days ago
American Airlines
Tue, Jun 10 - Wed, Jun 11
PIT
Pittsburgh
DSM
Des Moines
$257 Roundtrip, found 6 days ago
$257
Roundtrip
found 6 days ago
Select American Airlines flight, departing Tue, Jun 10 from Pittsburgh to Des Moines, returning Wed, Jun 11, priced at $257 found 6 days ago
Delta
Wed, May 28 - Tue, Jun 10
PIT
Pittsburgh
DSM
Des Moines
$257 Roundtrip, found 7 hours ago
$257
Roundtrip
found 7 hours ago
Select Delta flight, departing Wed, May 28 from Pittsburgh to Des Moines, returning Tue, Jun 10, priced at $257 found 7 hours ago
United
Wed, May 14 - Tue, May 20
PIT
Pittsburgh
DSM
Des Moines
$257 Roundtrip, found 3 days ago
$257
Roundtrip
found 3 days ago
Select United flight, departing Wed, May 14 from Pittsburgh to Des Moines, returning Tue, May 20, priced at $257 found 3 days ago
Delta
Wed, May 14 - Tue, May 20
PIT
Pittsburgh
DSM
Des Moines
$261 Roundtrip, found 3 days ago
$261
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, May 14 from Pittsburgh to Des Moines, returning Tue, May 20, priced at $261 found 3 days ago
Southwest Airlines
Tue, Jun 10 - Wed, Jun 11
PIT
Pittsburgh
DSM
Des Moines
$262 Roundtrip, found 6 days ago
$262
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Tue, Jun 10 from Pittsburgh to Des Moines, returning Wed, Jun 11, priced at $262 found 6 days ago
Southwest Airlines
Wed, May 14 - Tue, May 20
PIT
Pittsburgh
DSM
Des Moines
$272 Roundtrip, found 3 days ago
$272
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Wed, May 14 from Pittsburgh to Des Moines, returning Tue, May 20, priced at $272 found 3 days ago
Southwest Airlines
Wed, Jul 9 - Wed, Jul 16
PIT
Pittsburgh
DSM
Des Moines
$273 Roundtrip, found 9 hours ago
$273
Roundtrip
found 9 hours ago
Select Southwest Airlines flight, departing Wed, Jul 9 from Pittsburgh to Des Moines, returning Wed, Jul 16, priced at $273 found 9 hours ago
United
Sat, May 17 - Tue, May 20
PIT
Pittsburgh
DSM
Des Moines
$276 Roundtrip, found 9 hours ago
$276
Roundtrip
found 9 hours ago
Select United flight, departing Sat, May 17 from Pittsburgh to Des Moines, returning Tue, May 20, priced at $276 found 9 hours ago
Southwest Airlines
Tue, Jun 10 - Wed, Jun 11
PIT
Pittsburgh
DSM
Des Moines
$277 Roundtrip, found 6 days ago
$277
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Tue, Jun 10 from Pittsburgh to Des Moines, returning Wed, Jun 11, priced at $277 found 6 days ago
Flights from Pittsburgh (PIT) to Des Moines (DSM)
Origin airport
Pittsburgh Intl.
Destination airport
Des Moines Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$256
Distance
701 mi

Pittsburgh to Des Moines Flights

The cheapest times to fly from Pittsburgh to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Pittsburgh to Des Moines are during the month of June. You can find some of the cheapest flights from Pittsburgh to Des Moines with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Pittsburgh to Des Moines

Sunday is one of the best days to book for cheap flights from Pittsburgh to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Pittsburgh to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Pittsburgh to Des Moines in 2025. You can also book with separate airlines for your outbound and return journeys, from $129 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Pittsburgh to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Pittsburgh to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Pittsburgh Intl. Airport (PIT) to Des Moines Intl. Airport (DSM) cost?
Discover the latest flight deals from PIT to DSM by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from PIT to DSM?
The cheapest flights from PIT to DSM are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from PIT to DSM?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from PIT to DSM. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Pittsburgh Intl. Airport (PIT) to Des Moines Intl. Airport (DSM)?
You’ll have to book a flight with a layover if you’re traveling from Pittsburgh Intl. Airport (PIT) to Des Moines Intl. Airport (DSM). Direct flights don’t operate daily on this route. However, just filter your search to include one or more stops to find the best option for your trip.
What day of the week has the most flights from PIT to DSM?
Generally you’ll have the most choice when it comes to flights on a Friday. Tuesdays tend to be the quietest.* However, this can vary depending on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Pittsburgh Intl. Airport (PIT) to Des Moines Intl. Airport (DSM)?
Book a flight from Pittsburgh Intl. Airport (PIT) to Des Moines Intl. Airport (DSM) that leaves before 3 PM to reduce the risk of cancellations. Departures later than this are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Pittsburgh Intl. Airport (PIT) to Des Moines Intl. Airport (DSM) last-minute?
Booking your ticket from PIT to DSM just before your journey is typically more expensive. But if you’re flexible with your itinerary, you could score a cheap last-minute fare.
Is it cheaper to book a PIT to DSM flight and hotel package?
Compared with arranging hotels and flights separately, booking a PIT to DSM flight and hotel package with Expedia could result in significant savings. What’s more, having everything in one convenient place will take the stress out of travel planning. Just pick your flights and choose from our extensive range of stays, then personalize your trip with extras like tours and car rentals.
Can I cancel or change the date of my flight from Pittsburgh Intl. Airport (PIT) to Des Moines Intl. Airport (DSM)?
In most cases, you can modify or cancel your PIT to DSM flight. However, additional charges may apply, especially if your booking was made over 24 hours ago. Double-check your itinerary for the airline’s rules and fees on flight changes, or if you need further details, go to our Customer Service portal.

Explore a world of travel with Expedia

*Available to One Key members.