$222 Cheap Flights from Portland (PDX) to Panama City (PTY)

View $222 flight on Wed, Jun 11, 2025Opens in a new window
Find available prices by choosing your travel dates.

Cheap Flights from Portland to Panama City (PDX-PTY)

Prices were available within the past 7 days and start at $222 for one-way flights and $480 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Mon, Jul 21 - Wed, Aug 6
PDX
Portland
PTY
Panama City
$480 Roundtrip, found 8 hours ago
$480
Roundtrip
found 8 hours ago
Select Delta flight, departing Mon, Jul 21 from Portland to Panama City, returning Wed, Aug 6, priced at $480 found 8 hours ago
United
Tue, Jul 15 - Tue, Jul 29
PDX
Portland
PTY
Panama City
$480 Roundtrip, found 1 hour ago
$480
Roundtrip
found 1 hour ago
Select United flight, departing Tue, Jul 15 from Portland to Panama City, returning Tue, Jul 29, priced at $480 found 1 hour ago
American Airlines
Tue, Jul 15 - Tue, Jul 29
PDX
Portland
PTY
Panama City
$485 Roundtrip, found 1 hour ago
$485
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Tue, Jul 15 from Portland to Panama City, returning Tue, Jul 29, priced at $485 found 1 hour ago
United
Wed, Jul 16 - Thu, Jul 24
PDX
Portland
PTY
Panama City
$486 Roundtrip, found 2 days ago
$486
Roundtrip
found 2 days ago
Select United flight, departing Wed, Jul 16 from Portland to Panama City, returning Thu, Jul 24, priced at $486 found 2 days ago
United
Mon, Jul 7 - Mon, Jul 14
PDX
Portland
PTY
Panama City
$487 Roundtrip, found 1 hour ago
$487
Roundtrip
found 1 hour ago
Select United flight, departing Mon, Jul 7 from Portland to Panama City, returning Mon, Jul 14, priced at $487 found 1 hour ago
United
Tue, Jul 15 - Tue, Jul 29
PDX
Portland
PTY
Panama City
$490 Roundtrip, found 1 hour ago
$490
Roundtrip
found 1 hour ago
Select United flight, departing Tue, Jul 15 from Portland to Panama City, returning Tue, Jul 29, priced at $490 found 1 hour ago
United
Wed, Jul 23 - Thu, Aug 7
PDX
Portland
PTY
Panama City
$492 Roundtrip, found 8 hours ago
$492
Roundtrip
found 8 hours ago
Select United flight, departing Wed, Jul 23 from Portland to Panama City, returning Thu, Aug 7, priced at $492 found 8 hours ago
United
Mon, Aug 11 - Wed, Aug 20
PDX
Portland
PTY
Panama City
$494 Roundtrip, found 4 hours ago
$494
Roundtrip
found 4 hours ago
Select United flight, departing Mon, Aug 11 from Portland to Panama City, returning Wed, Aug 20, priced at $494 found 4 hours ago
avianca
Wed, Apr 30 - Thu, May 1
PDX
Portland
PTY
Panama City
$984 Roundtrip, found 16 hours ago
$984
Roundtrip
found 16 hours ago
Select avianca flight, departing Wed, Apr 30 from Portland to Panama City, returning Thu, May 1, priced at $984 found 16 hours ago
Copa
Thu, May 8 - Thu, May 15
PDX
Portland
PTY
Panama City
$1,371 Roundtrip, found 2 hours ago
$1,371
Roundtrip
found 2 hours ago
Select Copa flight, departing Thu, May 8 from Portland to Panama City, returning Thu, May 15, priced at $1,371 found 2 hours ago

Frequently asked questions

How much does a flight from Portland Intl. Airport (PDX) to Tocumen Intl. Airport (PTY) cost?
Discover the latest flight deals from PDX to PTY by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from PDX to PTY?
The cheapest flights from PDX to PTY are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from PDX to PTY?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from PDX to PTY. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Portland Intl. Airport (PDX) to Tocumen Intl. Airport (PTY)?
You’ll need to catch a flight with a layover when traveling from Portland Intl. Airport (PDX) to Tocumen Intl. Airport (PTY). There are no daily direct flights on this route. However, just filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from PDX to PTY?
You’ll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Portland Intl. Airport (PDX) to Tocumen Intl. Airport (PTY)?
To reach Tocumen Intl. Airport (PTY) without delays, select a flight that leaves Portland Intl. Airport (PDX) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Portland Intl. Airport (PDX) to Tocumen Intl. Airport (PTY) last-minute?
Last-minute bookings from PDX to PTY are usually more expensive. To secure the lowest rates, start searching for flights early. That being said, if you’re flexible with your travel plans, it’s possible to land a cheap fare right before your trip.
Is it cheaper to book a PDX to PTY flight and hotel package?
You’ll generally save money by securing a PDX to PTY flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it’s easy to manage it all in one place. After choosing your ideal flights and accommodations, consider other add-ons like activities, tours and car rentals.
Can I cancel or change the date of my flight from Portland Intl. Airport (PDX) to Tocumen Intl. Airport (PTY)?
You can usually reschedule or cancel your PDX to PTY flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Check your airline’s policies in your itinerary to see what changes are possible and if any costs are involved. You’ll also find more details on our Customer Service portal.
*Available to One Key members.