$224 Cheap Flights from Chicago (ORD) to Muscle Shoals (MSL)

View $224 flight on Sat, May 10, 2025Opens in a new window

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Find available prices by choosing your travel dates.

Cheap Flights from Chicago to Muscle Shoals (ORD-MSL)

Prices were available within the past 7 days and start at $224 for one-way flights and $327 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, May 27 - Sun, Jun 1
ORD
Chicago
MSL
Muscle Shoals
$327 Roundtrip, found 3 days ago
$327
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, May 27 from Chicago to Muscle Shoals, returning Sun, Jun 1, priced at $327 found 3 days ago
Contour Airlines
Sun, Jun 15 - Thu, Jun 19
ORD
Chicago
MSL
Muscle Shoals
$356 Roundtrip, found 18 hours ago
$356
Roundtrip
found 18 hours ago
Select Contour Airlines flight, departing Sun, Jun 15 from Chicago to Muscle Shoals, returning Thu, Jun 19, priced at $356 found 18 hours ago
American Airlines
Sun, May 25 - Sun, Jun 1
ORD
Chicago
MSL
Muscle Shoals
$362 Roundtrip, found 3 days ago
$362
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sun, May 25 from Chicago to Muscle Shoals, returning Sun, Jun 1, priced at $362 found 3 days ago
Contour Airlines
Sun, Jun 15 - Fri, Jun 20
ORD
Chicago
MSL
Muscle Shoals
$366 Roundtrip, found 18 hours ago
$366
Roundtrip
found 18 hours ago
Select Contour Airlines flight, departing Sun, Jun 15 from Chicago to Muscle Shoals, returning Fri, Jun 20, priced at $366 found 18 hours ago
American Airlines
Sat, May 24 - Sun, May 25
ORD
Chicago
MSL
Muscle Shoals
$368 Roundtrip, found 1 day ago
$368
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, May 24 from Chicago to Muscle Shoals, returning Sun, May 25, priced at $368 found 1 day ago
Contour Airlines
Thu, Jun 12 - Thu, Jun 19
ORD
Chicago
MSL
Muscle Shoals
$380 Roundtrip, found 18 hours ago
$380
Roundtrip
found 18 hours ago
Select Contour Airlines flight, departing Thu, Jun 12 from Chicago to Muscle Shoals, returning Thu, Jun 19, priced at $380 found 18 hours ago
Contour Airlines
Mon, Jun 16 - Thu, Jun 19
ORD
Chicago
MSL
Muscle Shoals
$385 Roundtrip, found 18 hours ago
$385
Roundtrip
found 18 hours ago
Select Contour Airlines flight, departing Mon, Jun 16 from Chicago to Muscle Shoals, returning Thu, Jun 19, priced at $385 found 18 hours ago
American Airlines
Wed, Jun 11 - Thu, Jun 19
ORD
Chicago
MSL
Muscle Shoals
$386 Roundtrip, found 18 hours ago
$386
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Wed, Jun 11 from Chicago to Muscle Shoals, returning Thu, Jun 19, priced at $386 found 18 hours ago
American Airlines
Tue, May 20 - Sat, May 24
ORD
Chicago
MSL
Muscle Shoals
$387 Roundtrip, found 1 day ago
$387
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, May 20 from Chicago to Muscle Shoals, returning Sat, May 24, priced at $387 found 1 day ago
Contour Airlines
Thu, Jun 12 - Fri, Jun 20
ORD
Chicago
MSL
Muscle Shoals
$390 Roundtrip, found 18 hours ago
$390
Roundtrip
found 18 hours ago
Select Contour Airlines flight, departing Thu, Jun 12 from Chicago to Muscle Shoals, returning Fri, Jun 20, priced at $390 found 18 hours ago
Flights from Chicago (ORD) to Muscle Shoals (MSL)
Origin airport
O'Hare Intl.
Destination airport
Northwest Alabama Regional
Roundtrip price
$327
Distance
499 mi

Chicago to Muscle Shoals Flights

The cheapest times to fly from Chicago to Muscle Shoals

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Chicago to Muscle Shoals are during the month of May. You can find some of the cheapest flights from Chicago to Muscle Shoals with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Chicago to Muscle Shoals

Sunday is one of the best days to book for cheap flights from Chicago to Muscle Shoals: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Chicago to Muscle Shoals

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Chicago to Muscle Shoals in 2025. You can also book with separate airlines for your outbound and return journeys, from $224 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Chicago to Muscle Shoals flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Chicago to Muscle Shoals airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from O'Hare Intl. Airport (ORD) to Northwest Alabama Regional Airport (MSL) cost?
Discover the latest flight deals from ORD to MSL by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from ORD to MSL?
The cheapest flights from ORD to MSL are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from ORD to MSL?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from ORD to MSL. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from O'Hare Intl. Airport (ORD) to Northwest Alabama Regional Airport (MSL)?
There are no daily nonstop flights departing from O’Hare Intl. Airport (ORD) to Northwest Alabama Regional Airport (MSL). But you can opt for flights with layovers. Filter your search results on Expedia to include one or more stops, and you’ll be cruising above the clouds in no time at all.
What day of the week has the most flights from ORD to MSL?
You’ll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from O'Hare Intl. Airport (ORD) to Northwest Alabama Regional Airport (MSL)?
To arrive at Northwest Alabama Regional Airport (MSL) without delays, book a flight that leaves O’Hare Intl. Airport (ORD) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
What airports do you fly into for Muscle Shoals from O'Hare Intl. Airport (ORD)?
If you’re taking a direct flight from O’Hare Intl. Airport (ORD) to Muscle Shoals, Huntsville Intl. Airport (HSV) is the only airport you can land at.
Is it cheaper to buy a plane ticket from O'Hare Intl. Airport (ORD) to Northwest Alabama Regional Airport (MSL) last-minute?
Last-minute bookings from ORD to MSL are usually more expensive. To lock in the lowest rates, start searching for flights well ahead of time. That being said, if your travel plans are flexible, it’s possible to find a cheap fare right before you leave.
Is it cheaper to book an ORD to MSL flight and hotel package?
You’ll typically save money by securing an ORD to MSL flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it’s simple to manage everything in one convenient place. Once you’ve chosen your ideal accommodations and flights, consider adding extras including activities, car rentals and tours.
Can I cancel or change the date of my flight from O'Hare Intl. Airport (ORD) to Northwest Alabama Regional Airport (MSL)?
In most instances, you’re able to cancel or reschedule your ORD to MSL flight. However, additional charges may apply, especially if your booking was made over 24 hours ago. Check your itinerary for the airline’s policies and fees on flight changes, or if you want further information, head to our Customer Service portal.

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*Available to One Key members.