Cheap Flights from Chicago (ORD) to Greenville (GMU)

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Find available prices by choosing your travel dates.
Flights from Chicago (ORD) to Greenville (GMU)
Origin airport
O'Hare Intl.
Destination airport
Greenville Downtown
Distance
576 mi

Chicago to Greenville Flights

The cheapest times to fly from Chicago to Greenville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Chicago to Greenville are during the month of . You can find some of the cheapest flights from Chicago to Greenville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Chicago to Greenville

Sunday is one of the best days to book for cheap flights from Chicago to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Chicago to Greenville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Chicago to Greenville in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Chicago to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Chicago to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from O'Hare Intl. Airport (ORD) to Greenville, SC (GMU-Greenville Downtown) cost?
Discover the latest flight deals from ORD to GMU by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from ORD to GMU?
The cheapest flights from ORD to GMU are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from ORD to GMU?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from ORD to GMU. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from O'Hare Intl. Airport (ORD) to Greenville, SC (GMU-Greenville Downtown)?
Direct flights from O’Hare Intl. Airport (ORD) to Greenville, SC (GMU-Greenville Downtown) aren’t available daily, so you’ll have to take a flight with a layover. Explore your options with Expedia’s filter tool. Enter your travel details and click on either “1 Stop” or “2+ Stops.”
What day of the week has the most flights from ORD to GMU?
Generally you’ll find the largest variety of flight choices on a Friday. Tuesdays are often the quietest.* However, this can change based on the time of year, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from O'Hare Intl. Airport (ORD) to Greenville, SC (GMU-Greenville Downtown)?
To avoid possible delays on the O’Hare Intl. Airport (ORD) to Greenville, SC (GMU-Greenville Downtown) route, travel before 3 PM. Departures after this time are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
What airports do you fly into for Greenville from O'Hare Intl. Airport (ORD)?
Take a direct flight from O’Hare Intl. Airport (ORD) to Greenville and touch down at Greenville-Spartanburg Intl. Airport (GSP). Another convenient gateway to this destination is Asheville Regional Airport (AVL).
Is it cheaper to buy a plane ticket from O'Hare Intl. Airport (ORD) to Greenville, SC (GMU-Greenville Downtown) last-minute?
Last-minute fares from ORD to GMU are typically more expensive. For the lowest prices, start searching for flights well in advance. That being said, if you can play around with your travel dates, you may land a cheap ticket right before your trip.
Is it cheaper to book an ORD to GMU flight and hotel package?
Compared with arranging flights and hotels separately, booking an ORD to GMU flight and hotel package with Expedia could lead to significant savings. Better still, having it all in one place will take the stress out of planning your trip. Simply secure your flights and select from our extensive range of hotels, then tailor your trip with extras like tours and car rentals.
Can I cancel or change the date of my flight from O'Hare Intl. Airport (ORD) to Greenville, SC (GMU-Greenville Downtown)?
In most cases, you’re able to reschedule or cancel your ORD to GMU flight. However, additional charges may apply, especially if you booked more than 24 hours ago. Double-check your itinerary for the airline’s fees and policies on flight changes, or if you need further information, head to our Customer Service portal.

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*Available to One Key members.