$330 Cheap Flights from Chicago (ORD) to Brussels (BRU)

View $330 flight on Mon, Jul 21, 2025Opens in a new window

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Find available prices by choosing your travel dates.

Cheap Flights from Chicago to Brussels (ORD-BRU)

Prices were available within the past 7 days and start at $330 for one-way flights and $379 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Scandinavian Airlines
Tue, Oct 14 - Wed, Oct 22
ORD
Chicago
BRU
Brussels
$379 Roundtrip, just found
$379
Roundtrip
just found
Select Scandinavian Airlines flight, departing Tue, Oct 14 from Chicago to Brussels, returning Wed, Oct 22, priced at $379 just found
Aer Lingus
Wed, Apr 30 - Fri, May 9
ORD
Chicago
BRU
Brussels
$562 Roundtrip, found 2 days ago
$562
Roundtrip
found 2 days ago
Select Aer Lingus flight, departing Wed, Apr 30 from Chicago to Brussels, returning Fri, May 9, priced at $562 found 2 days ago
TAP Portugal
Fri, Oct 17 - Thu, Oct 23
ORD
Chicago
BRU
Brussels
$600 Roundtrip, just found
$600
Roundtrip
just found
Select TAP Portugal flight, departing Fri, Oct 17 from Chicago to Brussels, returning Thu, Oct 23, priced at $600 just found
Turkish Airlines
Wed, Oct 15 - Tue, Oct 21
ORD
Chicago
BRU
Brussels
$616 Roundtrip, just found
$616
Roundtrip
just found
Select Turkish Airlines flight, departing Wed, Oct 15 from Chicago to Brussels, returning Tue, Oct 21, priced at $616 just found
Iberia
Tue, Sep 9 - Wed, Sep 17
ORD
Chicago
BRU
Brussels
$700 Roundtrip, found 3 days ago
$700
Roundtrip
found 3 days ago
Select Iberia flight, departing Tue, Sep 9 from Chicago to Brussels, returning Wed, Sep 17, priced at $700 found 3 days ago
Icelandair
Thu, Dec 4 - Fri, Dec 12
ORD
Chicago
BRU
Brussels
$754 Roundtrip, found 3 days ago
$754
Roundtrip
found 3 days ago
Select Icelandair flight, departing Thu, Dec 4 from Chicago to Brussels, returning Fri, Dec 12, priced at $754 found 3 days ago
JetBlue Airways
Mon, Aug 25 - Wed, Sep 3
ORD
Chicago
ZYR
Brussels
$780 Roundtrip, found 3 hours ago
$780
Roundtrip
found 3 hours ago
Select JetBlue Airways flight, departing Mon, Aug 25 from Chicago to Brussels, returning Wed, Sep 3, priced at $780 found 3 hours ago
United
Mon, Dec 8 - Tue, Dec 16
ORD
Chicago
BRU
Brussels
$789 Roundtrip, found 2 days ago
$789
Roundtrip
found 2 days ago
Select United flight, departing Mon, Dec 8 from Chicago to Brussels, returning Tue, Dec 16, priced at $789 found 2 days ago
Air Canada
Wed, Jul 30 - Wed, Aug 20
ORD
Chicago
BRU
Brussels
$790 Roundtrip, found 1 hour ago
$790
Roundtrip
found 1 hour ago
Select Air Canada flight, departing Wed, Jul 30 from Chicago to Brussels, returning Wed, Aug 20, priced at $790 found 1 hour ago
Virgin Atlantic
Mon, Dec 8 - Tue, Dec 16
ORD
Chicago
BRU
Brussels
$804 Roundtrip, found 2 days ago
$804
Roundtrip
found 2 days ago
Select Virgin Atlantic flight, departing Mon, Dec 8 from Chicago to Brussels, returning Tue, Dec 16, priced at $804 found 2 days ago
Flights from Chicago (ORD) to Brussels (BRU)
Origin airport
O'Hare Intl.
Destination airport
Brussels - National
Airlines serving
Aer Lingus, Air Canada, American Airlines, Austrian Airlines, British Airways, Brussels Airlines, Delta, Finnair, ITA Airways, Iberia, Icelandair, KLM, LOT-Polish Airlines, Lufthansa, Scandinavian Airlines, Swiss International Air Lines, TAP Portugal, Turkish Airlines, United, Virgin Atlantic
Roundtrip price
$378
Distance
4147 mi

Chicago to Brussels Flights

The cheapest times to fly from Chicago to Brussels

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Chicago to Brussels are during the month of October. You can find some of the cheapest flights from Chicago to Brussels with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Chicago to Brussels

Sunday is one of the best days to book for cheap flights from Chicago to Brussels: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Chicago to Brussels

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Chicago to Brussels in 2025. You can also book with separate airlines for your outbound and return journeys, from $330 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Chicago to Brussels flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Chicago to Brussels airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How long does it take to fly from O'Hare Airport to BRU?
With United Airlines, a direct flight takes about 8 hours and 5 minutes. Step on board the 5:55PM flight from ORD and land at Brussels Airport at 9:00AM. Get your hands on a fantastic deal on this and other routes when you book your ticket with Expedia.
Is it cheaper to buy a plane ticket from O'Hare Airport to BRU last minute?
When it comes to booking your flights, it’s always better to be prepared. While it’s possible to pick up a last-minute deal on an O’Hare Airport to BRU flight, fares usually don’t get cheaper as the departure date nears. Based on flight pricing and demand studies in 2022, we have found that the sweet spot to book a domestic flight is between 28 – 35 days in advance. For international trips it’s three to four months.
What airline has the least delays from O'Hare Airport to BRU?
If you don’t want to be waiting around for hours — or worse, have your vacation ruined due to a flight delay — take off with United Airlines. Around 61% of its O’Hare Intl. Airport (ORD) to Brussels Airport services touch down on time. You can look up your flight status before leaving for the airport through the Expedia App. It also delivers real-time notifications about other vital info, such as any gate changes, luggage carousel numbers and how to reach your hotel. Keep all the details in your pocket with this all-in-one travel companion.
What airports do you fly into for Brussels from Chicago?
With Brussels - National Airport (BRU), Antwerp Intl. Airport (ANR) and Malle (OBL-Zoersel-Oostmalle Airfield) to pick from, making your way from Chicago to Brussels is a piece of cake. The city’s main gateway, Brussels - National Airport (BRU), is approximately 7 mi northeast of the center. Along with the price of fares, consider factors like the ease of getting from the airport and the distance to your hotel when choosing where to fly into. Get your Brussels vacation off to an exciting start by checking out La Grand Place and Atomium.
What are the most popular departure times for flights from O'Hare Airport to Brussels - National Airport (BRU)?
The most popular departure times for flights from ORD to Brussels Airport fall between 5:00 PM - 6:00 PM on United Airlines. One helpful tip is to depart in the morning. The earlier you take off, the greater your chances of a delay-free flight with lighter air traffic in the sky.
Can I change the date of my flight from O'Hare Airport to Brussels - National Airport (BRU)?
Make changes quickly to your ORD to BRU journey through the Expedia Trips portal. But before you begin, browse the rules in your itinerary to find out what the airline will let you do and what fees apply for changes. Some airlines charge a change fee per person, in addition to any difference in fares. But if you booked in the last 24 hours, you may be able to cancel for free and arrange new flights. You can also head to our Customer Service portal for more advice and to connect with our Virtual Agent.

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*Available to One Key members.