Cheap Flights from Colon (ONX) to Panama City (PTY)

Featured airlines

American Airlines
United
Southwest Airlines
Delta
Spirit Airlines
JetBlue Airways
Frontier Airlines
Air India
Hawaiian Airlines

  • Plan, book, fly with confidence

  • trending down icon
    Be in the know
    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon
    Book smarter
    Save up to 30% on select hotels after you book a flight*
  • one key icon
    Earn twice
    Earn your airline miles on top of our OneKeyCash
    Learn about One Key
Find available prices by choosing your travel dates.
Flights from Colon (ONX) to Panama City (PTY)
Origin airport
Enrique Adolfo Jimenez
Destination airport
Tocumen Intl.
Distance
38 mi

Colon to Panama City Flights

The cheapest times to fly from Colon to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Colon to Panama City are during the month of . You can find some of the cheapest flights from Colon to Panama City with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Colon to Panama City

Sunday is one of the best days to book for cheap flights from Colon to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Colon to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Colon to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Colon to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Colon to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

Is it cheaper to buy a plane ticket from ONX to PTY last minute?
When it comes to booking your flights, it’s better to be prepared. While it’s possible to pick up a deal on an ONX to Panama Airport flight at the last minute, fares usually don’t get cheaper as the date of departure nears. Based on flight pricing and demand studies in 2022, we have found that the sweet spot to book a domestic flight is between 28 – 35 days in advance. For international travel it’s between three and four months.
What airports do you fly into for Panama City from Colon?
From Colon, you can travel to Panama City via Tocumen Intl. Airport (PTY), Marcos A. Gelabert Intl. Airport (PAC) and Panama Pacifico Intl. Airport (BLB). It’s wise to check which hub is best for you before making your decision. If you go with Tocumen Intl. Airport (PTY), it’s around 11 mi northeast of downtown. Use the dough you save when booking your airfare with Expedia to experience the city’s popular sights, such as Miraflores Locks and Metropolitan Cathedral of Panama.
Can I change the date of my flight from ONX to Panama Airport?
Life can throw a spanner in your plans, so Expedia is here to help make things as easy as possible. First, find your ONX to Tocumen Intl. Airport (PTY) itinerary through the Expedia Trips portal and look up the fare conditions and rules about change fees or other charges. If you purchased your airfare in the last 24 hours, some airlines will let you cancel for free and organize new flights. If you booked your fare more than 24 hours ago, get in touch with us through our Customer Service portal so we can assist you further.

Explore a world of travel with Expedia

*Available to One Key members.