$488 Cheap Flights from Myrtle Beach (MYR) to Rome (FCO)

View $488 flight on Sun, Oct 19, 2025Opens in a new window

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Find available prices by choosing your travel dates.

Cheap Flights from Myrtle Beach to Rome (MYR-FCO)

Prices were available within the past 7 days and start at $488 for one-way flights and $650 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Mon, Oct 27 - Tue, Nov 4
MYR
Myrtle Beach
FCO
Rome
$650 Roundtrip, found 6 days ago
$650
Roundtrip
found 6 days ago
Select United flight, departing Mon, Oct 27 from Myrtle Beach to Rome, returning Tue, Nov 4, priced at $650 found 6 days ago
United
Sat, Oct 25 - Tue, Nov 4
MYR
Myrtle Beach
FCO
Rome
$655 Roundtrip, found 6 days ago
$655
Roundtrip
found 6 days ago
Select United flight, departing Sat, Oct 25 from Myrtle Beach to Rome, returning Tue, Nov 4, priced at $655 found 6 days ago
Delta
Tue, Oct 28 - Tue, Nov 4
MYR
Myrtle Beach
FCO
Rome
$668 Roundtrip, found 6 days ago
$668
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Oct 28 from Myrtle Beach to Rome, returning Tue, Nov 4, priced at $668 found 6 days ago
British Airways
Tue, Oct 21 - Tue, Nov 4
MYR
Myrtle Beach
FCO
Rome
$671 Roundtrip, found 2 days ago
$671
Roundtrip
found 2 days ago
Select British Airways flight, departing Tue, Oct 21 from Myrtle Beach to Rome, returning Tue, Nov 4, priced at $671 found 2 days ago
American Airlines
Mon, Nov 3 - Thu, Nov 13
MYR
Myrtle Beach
FCO
Rome
$673 Roundtrip, found 5 days ago
$673
Roundtrip
found 5 days ago
Select American Airlines flight, departing Mon, Nov 3 from Myrtle Beach to Rome, returning Thu, Nov 13, priced at $673 found 5 days ago
British Airways
Mon, Nov 3 - Thu, Nov 13
MYR
Myrtle Beach
FCO
Rome
$675 Roundtrip, found 5 days ago
$675
Roundtrip
found 5 days ago
Select British Airways flight, departing Mon, Nov 3 from Myrtle Beach to Rome, returning Thu, Nov 13, priced at $675 found 5 days ago
British Airways
Tue, Oct 21 - Tue, Nov 4
MYR
Myrtle Beach
FCO
Rome
$677 Roundtrip, found 2 days ago
$677
Roundtrip
found 2 days ago
Select British Airways flight, departing Tue, Oct 21 from Myrtle Beach to Rome, returning Tue, Nov 4, priced at $677 found 2 days ago
British Airways
Mon, Nov 3 - Thu, Nov 13
MYR
Myrtle Beach
FCO
Rome
$681 Roundtrip, found 5 days ago
$681
Roundtrip
found 5 days ago
Select British Airways flight, departing Mon, Nov 3 from Myrtle Beach to Rome, returning Thu, Nov 13, priced at $681 found 5 days ago
British Airways
Tue, Oct 21 - Tue, Nov 4
MYR
Myrtle Beach
FCO
Rome
$681 Roundtrip, found 2 days ago
$681
Roundtrip
found 2 days ago
Select British Airways flight, departing Tue, Oct 21 from Myrtle Beach to Rome, returning Tue, Nov 4, priced at $681 found 2 days ago
Air Canada
Wed, Feb 11 - Tue, Feb 17
MYR
Myrtle Beach
FCO
Rome
$719 Roundtrip, found 3 days ago
$719
Roundtrip
found 3 days ago
Select Air Canada flight, departing Wed, Feb 11 from Myrtle Beach to Rome, returning Tue, Feb 17, priced at $719 found 3 days ago
Flights from Myrtle Beach (MYR) to Rome (FCO)
Origin airport
Myrtle Beach Intl.
Destination airport
Fiumicino - Leonardo da Vinci Intl.
Airlines serving
Air Canada, Air France, American Airlines, British Airways, Delta, KLM, Scandinavian Airlines, United
Roundtrip price
$649
Distance
4773 mi

Myrtle Beach to Rome Flights

The cheapest times to fly from Myrtle Beach to Rome

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Myrtle Beach to Rome are during the month of October. You can find some of the cheapest flights from Myrtle Beach to Rome with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Myrtle Beach to Rome

Sunday is one of the best days to book for cheap flights from Myrtle Beach to Rome: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Myrtle Beach to Rome

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Myrtle Beach to Rome in 2025. You can also book with separate airlines for your outbound and return journeys, from $488 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Myrtle Beach to Rome flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Myrtle Beach to Rome airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Myrtle Beach Intl. Airport (MYR) to Fiumicino - Leonardo da Vinci Intl. Airport (FCO) cost?
Discover the latest flight deals from MYR to FCO by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from MYR to FCO?
The cheapest flights from MYR to FCO are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from MYR to FCO?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from MYR to FCO. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Myrtle Beach Intl. Airport (MYR) to Fiumicino - Leonardo da Vinci Intl. Airport (FCO)?
There are no daily nonstop flights from Myrtle Beach Intl. Airport (MYR) to Fiumicino - Leonardo da Vinci Intl. Airport (FCO). But you can choose flights with layovers. Filter your search on Expedia to include one or two stops, and you’ll be cruising above the clouds in no time.
What day of the week has the most flights from MYR to FCO?
Typically you’ll find the widest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* But this can change based on the time of year, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Myrtle Beach Intl. Airport (MYR) to Fiumicino - Leonardo da Vinci Intl. Airport (FCO)?
To land at Fiumicino - Leonardo da Vinci Intl. Airport (FCO) on schedule, choose a flight that leaves from Myrtle Beach Intl. Airport (MYR) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Myrtle Beach Intl. Airport (MYR) to Fiumicino - Leonardo da Vinci Intl. Airport (FCO) last-minute?
Booking your plane ticket from MYR to FCO shortly before your trip is typically more expensive. However, if you’re flexible with your departure times and dates, you could snag a cheap last-minute fare.
Is it cheaper to book a MYR to FCO flight and hotel package?
You can save money by securing a MYR to FCO flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it’s easy to manage everything in one place. After choosing your preferred flights and accommodations, you can add extras such as activities, car rentals and tours.
Can I cancel or change the date of my flight from Myrtle Beach Intl. Airport (MYR) to Fiumicino - Leonardo da Vinci Intl. Airport (FCO)?
If you reserved your MYR to FCO flight in the last 24 hours, you may be able to cancel or modify it without fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal if you’d like more information.

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*Available to One Key members.