$107 Cheap Flights from Myrtle Beach (MYR) to Charlotte (CLT)

View $107 flight on Tue, Jun 24, 2025Opens in a new window

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Find available prices by choosing your travel dates.

Cheap Flights from Myrtle Beach to Charlotte (MYR-CLT)

Prices were available within the past 7 days and start at $107 for one-way flights and $207 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Spirit Airlines
Sat, May 10 - Thu, May 15
MYR
Myrtle Beach
CLT
Charlotte
$207 Roundtrip, found 6 days ago
$207
Roundtrip
found 6 days ago
Select Spirit Airlines flight, departing Sat, May 10 from Myrtle Beach to Charlotte, returning Thu, May 15, priced at $207 found 6 days ago
Spirit Airlines
Wed, Jun 11 - Tue, Jun 17
MYR
Myrtle Beach
CLT
Charlotte
$229 Roundtrip, found 1 day ago
$229
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Wed, Jun 11 from Myrtle Beach to Charlotte, returning Tue, Jun 17, priced at $229 found 1 day ago
Spirit Airlines
Sat, May 17 - Sat, May 24
MYR
Myrtle Beach
CLT
Charlotte
$230 Roundtrip, found 1 day ago
$230
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Sat, May 17 from Myrtle Beach to Charlotte, returning Sat, May 24, priced at $230 found 1 day ago
Spirit Airlines
Tue, May 13 - Thu, May 15
MYR
Myrtle Beach
CLT
Charlotte
$231 Roundtrip, found 3 days ago
$231
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Tue, May 13 from Myrtle Beach to Charlotte, returning Thu, May 15, priced at $231 found 3 days ago
Spirit Airlines
Wed, Jun 11 - Sat, Jun 14
MYR
Myrtle Beach
CLT
Charlotte
$234 Roundtrip, found 1 day ago
$234
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Wed, Jun 11 from Myrtle Beach to Charlotte, returning Sat, Jun 14, priced at $234 found 1 day ago
Spirit Airlines
Thu, May 22 - Sat, May 24
MYR
Myrtle Beach
CLT
Charlotte
$237 Roundtrip, found 11 hours ago
$237
Roundtrip
found 11 hours ago
Select Spirit Airlines flight, departing Thu, May 22 from Myrtle Beach to Charlotte, returning Sat, May 24, priced at $237 found 11 hours ago
Southwest Airlines
Tue, Jun 10 - Tue, Jun 17
MYR
Myrtle Beach
CLT
Charlotte
$266 Roundtrip, found 16 hours ago
$266
Roundtrip
found 16 hours ago
Select Southwest Airlines flight, departing Tue, Jun 10 from Myrtle Beach to Charlotte, returning Tue, Jun 17, priced at $266 found 16 hours ago
American Airlines
Sat, Jun 21 - Sat, Jun 28
MYR
Myrtle Beach
CLT
Charlotte
$281 Roundtrip, found 7 hours ago
$281
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Sat, Jun 21 from Myrtle Beach to Charlotte, returning Sat, Jun 28, priced at $281 found 7 hours ago
United
Tue, Jun 24 - Tue, Jul 1
MYR
Myrtle Beach
CLT
Charlotte
$301 Roundtrip, found 4 days ago
$301
Roundtrip
found 4 days ago
Select United flight, departing Tue, Jun 24 from Myrtle Beach to Charlotte, returning Tue, Jul 1, priced at $301 found 4 days ago
Delta
Fri, Jun 27 - Sun, Jun 29
MYR
Myrtle Beach
CLT
Charlotte
$427 Roundtrip, found 4 days ago
$427
Roundtrip
found 4 days ago
Select Delta flight, departing Fri, Jun 27 from Myrtle Beach to Charlotte, returning Sun, Jun 29, priced at $427 found 4 days ago
Flights from Myrtle Beach (MYR) to Charlotte (CLT)
Origin airport
Myrtle Beach Intl.
Destination airport
Charlotte-Douglas Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, Spirit Airlines, United
Roundtrip price
$207
Distance
156 mi

Myrtle Beach to Charlotte Flights

The cheapest times to fly from Myrtle Beach to Charlotte

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Myrtle Beach to Charlotte are during the month of May. You can find some of the cheapest flights from Myrtle Beach to Charlotte with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Myrtle Beach to Charlotte

Sunday is one of the best days to book for cheap flights from Myrtle Beach to Charlotte: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Myrtle Beach to Charlotte

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Myrtle Beach to Charlotte in 2025. You can also book with separate airlines for your outbound and return journeys, from $107 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Myrtle Beach to Charlotte flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Myrtle Beach to Charlotte airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Myrtle Beach Intl. Airport (MYR) to Charlotte-Douglas Intl. Airport (CLT) cost?
Discover the latest flight deals from MYR to CLT by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from MYR to CLT?
The cheapest flights from MYR to CLT are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Myrtle Beach Intl. Airport (MYR) to Charlotte-Douglas Intl. Airport (CLT)?
If you’re departing from Myrtle Beach Intl. Airport (MYR), you can board a nonstop flight to Charlotte-Douglas Intl. Airport (CLT) with American Airlines.
What is the cheapest airline that flies from MYR to CLT?
Right now, the cheapest airline operating one-way flights from MYR to CLT is American Airlines. You can book a seat on this route from $141. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from MYR on June 25 2025. Prices were last updated on April 22 2025 and have not changed since.
How many flights per day from Myrtle Beach Intl. Airport (MYR) to Charlotte-Douglas Intl. Airport (CLT)?
When departing from Myrtle Beach Intl. Airport (MYR), you can pick from an average of 7 daily nonstop flights to Charlotte-Douglas Intl. Airport (CLT).
What are the most popular departure times for flights from Myrtle Beach Intl. Airport (MYR) to Charlotte-Douglas Intl. Airport (CLT)?
The 5 AM departures from MYR to CLT see the highest demand. They can also be more expensive. If you want to save money, choose a less crowded time to fly.
What day of the week has the most flights from MYR to CLT?
Fly on a Saturday if you’re looking for the biggest selection of flights from Myrtle Beach Intl. Airport (MYR) to Charlotte-Douglas Intl. Airport (CLT).
What is the earliest flight from Myrtle Beach Intl. Airport (MYR) to Charlotte-Douglas Intl. Airport (CLT)?
The earliest flight leaving from Myrtle Beach Intl. Airport (MYR) is at around 5:05AM UTC-5. Board this plane and you’ll touch down at Charlotte-Douglas Intl. Airport (CLT) at approximately 6:14AM UTC-5. The total flight duration is 1h 9m.
How long does it take to fly from Myrtle Beach Intl. Airport (MYR) to Charlotte-Douglas Intl. Airport (CLT)?
The average flight time from MYR to CLT is 1 hour and 14 minutes, covering a distance of 160 mi.
What airline has the least delays from MYR to CLT?
Consider traveling with American Airlines if you’d like to fly straight from Myrtle Beach Intl. Airport (MYR) to Charlotte-Douglas Intl. Airport (CLT) without any delays. This airline has the strongest track record for punctuality, with an on-time performance of 84%. Want to get notified of any changes? You can check your flight status using the Expedia App.
What is the best time to fly from Myrtle Beach Intl. Airport (MYR) to Charlotte-Douglas Intl. Airport (CLT)?
Choose a flight from Myrtle Beach Intl. Airport (MYR) to Charlotte-Douglas Intl. Airport (CLT) that leaves before 3 PM to reduce the risk of cancellations. Departures later than this have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
What airports do you fly into for Charlotte from Myrtle Beach Intl. Airport (MYR)?
Browse your flight options from Myrtle Beach Intl. Airport (MYR) to Charlotte-Douglas Intl. Airport (CLT). This is the only airport in Charlotte you can fly into if you’re taking a direct flight.
Is it cheaper to buy a plane ticket from Myrtle Beach Intl. Airport (MYR) to Charlotte-Douglas Intl. Airport (CLT) last-minute?
Booking your flight from MYR to CLT right before your journey is typically more expensive. But if you’re flexible with your travel times and dates, you could bag a cheap last-minute fare.
Is it cheaper to book a MYR to CLT flight and hotel package?
You’ll typically save money by securing a MYR to CLT flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it’s easy to manage it all in one convenient place. Once you’ve chosen your ideal flights and accommodations, consider other add-ons like car rentals, activities and tours.
Can I cancel or change the date of my flight from Myrtle Beach Intl. Airport (MYR) to Charlotte-Douglas Intl. Airport (CLT)?
If you reserved your MYR to CLT flight within the last 24 hours, you may be able to cancel or modify it without any fees. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you’d like more information.

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*Available to One Key members.