$110 Cheap Flights from New Orleans (MSY) to St. Louis (STL)

View $110 flight on Fri, May 16, 2025Opens in a new window

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Find available prices by choosing your travel dates.

Cheap Flights from New Orleans to St. Louis (MSY-STL)

Prices were available within the past 7 days and start at $110 for one-way flights and $198 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Fri, May 2 - Sat, May 3
MSY
New Orleans
STL
St. Louis
$198 Roundtrip, found 4 hours ago
$198
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Fri, May 2 from New Orleans to St. Louis, returning Sat, May 3, priced at $198 found 4 hours ago
Frontier Airlines
Fri, May 9 - Mon, May 12
MSY
New Orleans
STL
St. Louis
$208 Roundtrip, found 1 day ago
$208
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Fri, May 9 from New Orleans to St. Louis, returning Mon, May 12, priced at $208 found 1 day ago
Frontier Airlines
Sun, May 4 - Wed, May 7
MSY
New Orleans
STL
St. Louis
$218 Roundtrip, found 4 hours ago
$218
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Sun, May 4 from New Orleans to St. Louis, returning Wed, May 7, priced at $218 found 4 hours ago
Frontier Airlines
Fri, May 2 - Mon, May 5
MSY
New Orleans
STL
St. Louis
$228 Roundtrip, found 4 hours ago
$228
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Fri, May 2 from New Orleans to St. Louis, returning Mon, May 5, priced at $228 found 4 hours ago
Frontier Airlines
Tue, May 20 - Thu, May 22
MSY
New Orleans
STL
St. Louis
$230 Roundtrip, found 1 day ago
$230
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Tue, May 20 from New Orleans to St. Louis, returning Thu, May 22, priced at $230 found 1 day ago
Frontier Airlines
Thu, May 29 - Sat, Jun 14
MSY
New Orleans
STL
St. Louis
$231 Roundtrip, found 1 day ago
$231
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, May 29 from New Orleans to St. Louis, returning Sat, Jun 14, priced at $231 found 1 day ago
American Airlines
Wed, Jun 18 - Mon, Jun 23
MSY
New Orleans
STL
St. Louis
$236 Roundtrip, found 4 hours ago
$236
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Wed, Jun 18 from New Orleans to St. Louis, returning Mon, Jun 23, priced at $236 found 4 hours ago
Delta
Wed, May 14 - Sat, May 17
MSY
New Orleans
STL
St. Louis
$244 Roundtrip, found 1 day ago
$244
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, May 14 from New Orleans to St. Louis, returning Sat, May 17, priced at $244 found 1 day ago
Southwest Airlines
Wed, May 14 - Sat, May 17
MSY
New Orleans
STL
St. Louis
$251 Roundtrip, found 1 day ago
$251
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Wed, May 14 from New Orleans to St. Louis, returning Sat, May 17, priced at $251 found 1 day ago
United
Tue, May 20 - Wed, May 21
MSY
New Orleans
STL
St. Louis
$281 Roundtrip, found 2 days ago
$281
Roundtrip
found 2 days ago
Select United flight, departing Tue, May 20 from New Orleans to St. Louis, returning Wed, May 21, priced at $281 found 2 days ago

Frequently asked questions

How much does a flight from Louis Armstrong New Orleans Intl. Airport (MSY) to Lambert-St. Louis Intl. Airport (STL) cost?
Cheap round-trip flights from Louis Armstrong New Orleans Intl. Airport (MSY) to Lambert-St. Louis Intl. Airport (STL) start at $305. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Southwest Airlines flight leaving MSY on May 14 2025 and touching down at STL. The price was last updated on April 22 2025 and has not changed since.
What is the cheapest month to fly from MSY to STL?
The cheapest flights from MSY to STL are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Louis Armstrong New Orleans Intl. Airport (MSY) to Lambert-St. Louis Intl. Airport (STL)?
Jump on a direct flight with Southwest Airlines and go straight from Louis Armstrong New Orleans Intl. Airport (MSY) to Lambert-St. Louis Intl. Airport (STL).
What is the cheapest airline that flies from MSY to STL?
With fares starting at $136 for a one-way journey from MSY to STL, Southwest Airlines is currently the cheapest carrier operating this route. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from MSY on May 28 2025. Prices were last updated on April 22 2025 and have not changed since.
How many flights per day from Louis Armstrong New Orleans Intl. Airport (MSY) to Lambert-St. Louis Intl. Airport (STL)?
When departing from Louis Armstrong New Orleans Intl. Airport (MSY), you’ll have a choice from an average of 2 daily direct flights to Lambert-St. Louis Intl. Airport (STL).
What are the most popular departure times for flights from Louis Armstrong New Orleans Intl. Airport (MSY) to Lambert-St. Louis Intl. Airport (STL)?
The 7 AM departures from MSY to STL are typically the busiest. Greater demand means you’ll likely pay more for these departures. If you’re hoping to save money, book during off-peak hours.
What day of the week has the most flights from MSY to STL?
Friday offers the most flights from Louis Armstrong New Orleans Intl. Airport (MSY) to Lambert-St. Louis Intl. Airport (STL). Consider leaving on this day and you’ll have a greater chance of finding a departure that fits your itinerary.
What is the earliest flight from Louis Armstrong New Orleans Intl. Airport (MSY) to Lambert-St. Louis Intl. Airport (STL)?
Hop on the earliest flight at around 7:30AM UTC-6, heading out of Louis Armstrong New Orleans Intl. Airport (MSY). You’ll be traveling for around 1h 50m, coming in to land at Lambert-St. Louis Intl. Airport (STL) at approximately 9:20AM UTC-6.
How long does it take to fly from Louis Armstrong New Orleans Intl. Airport (MSY) to Lambert-St. Louis Intl. Airport (STL)?
It takes around 1 hour and 50 minutes to travel the 610 mi from MSY to STL.
What airline has the least delays from MSY to STL?
With 82% of journeys usually arriving on schedule, Southwest Airlines has the best on-time performance for nonstop flights from Louis Armstrong New Orleans Intl. Airport (MSY) to Lambert-St. Louis Intl. Airport (STL). To keep track of your flight status and get notified if anything changes, simply head to the Expedia App.
What is the best time to fly from Louis Armstrong New Orleans Intl. Airport (MSY) to Lambert-St. Louis Intl. Airport (STL)?
Choose a flight from Louis Armstrong New Orleans Intl. Airport (MSY) to Lambert-St. Louis Intl. Airport (STL) that takes off before 3 PM to reduce the likelihood of delays and cancellations. Departures later than this are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
What airports do you fly into for St. Louis from Louis Armstrong New Orleans Intl. Airport (MSY)?
Check out your flight options from Louis Armstrong New Orleans Intl. Airport (MSY) to Lambert-St. Louis Intl. Airport (STL). This is the only St. Louis airport you can touch down at if you’re taking a direct flight.
Is it cheaper to buy a plane ticket from Louis Armstrong New Orleans Intl. Airport (MSY) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Booking your flight from MSY to STL just before your trip is typically more expensive. But if you’re flexible with your departure dates and times, you could land a cheap last-minute fare.
Is it cheaper to book a MSY to STL flight and hotel package?
You’ll typically save money by securing a MSY to STL flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it’s simple to manage it all in one convenient place. Once you’ve selected your ideal accommodations and flights, consider adding extras such as tours, activities and car rentals.
Can I cancel or change the date of my flight from Louis Armstrong New Orleans Intl. Airport (MSY) to Lambert-St. Louis Intl. Airport (STL)?
In most instances, you can cancel or modify your MSY to STL flight. However, additional fees may apply, especially if you booked over 24 hours ago. Check your itinerary for the airline’s guidelines and fees on flight changes, or if you’d like more information, go to our Customer Service portal.
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