$130 Cheap Flights from Minneapolis (MSP) to Knoxville (TYS)

View $130 flight on Thu, Jun 5, 2025Opens in a new window

Popular airlines from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS)

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Find available prices by choosing your travel dates.

Cheap Flights from Minneapolis to Knoxville (MSP-TYS)

Prices were available within the past 7 days and start at $130 for one-way flights and $228 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Sun, May 25 - Thu, May 29
MSP
Minneapolis
TYS
Knoxville
$228 Roundtrip, found 1 day ago
$228
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sun, May 25 from Minneapolis to Knoxville, returning Thu, May 29, priced at $228 found 1 day ago
Frontier Airlines
Thu, Jun 5 - Sun, Jun 8
MSP
Minneapolis
TYS
Knoxville
$248 Roundtrip, found 8 hours ago
$248
Roundtrip
found 8 hours ago
Select Frontier Airlines flight, departing Thu, Jun 5 from Minneapolis to Knoxville, returning Sun, Jun 8, priced at $248 found 8 hours ago
American Airlines
Thu, Jul 10 - Tue, Jul 15
MSP
Minneapolis
TYS
Knoxville
$269 Roundtrip, found 2 hours ago
$269
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Thu, Jul 10 from Minneapolis to Knoxville, returning Tue, Jul 15, priced at $269 found 2 hours ago
Frontier Airlines
Sun, Jun 1 - Thu, Jun 12
MSP
Minneapolis
TYS
Knoxville
$271 Roundtrip, found 3 days ago
$271
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Sun, Jun 1 from Minneapolis to Knoxville, returning Thu, Jun 12, priced at $271 found 3 days ago
Frontier Airlines
Thu, May 22 - Sun, May 25
MSP
Minneapolis
TYS
Knoxville
$280 Roundtrip, just found
$280
Roundtrip
just found
Select Frontier Airlines flight, departing Thu, May 22 from Minneapolis to Knoxville, returning Sun, May 25, priced at $280 just found
Frontier Airlines
Thu, May 22 - Sun, Jun 1
MSP
Minneapolis
TYS
Knoxville
$290 Roundtrip, found 1 day ago
$290
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, May 22 from Minneapolis to Knoxville, returning Sun, Jun 1, priced at $290 found 1 day ago
Frontier Airlines
Thu, Aug 14 - Sun, Aug 17
MSP
Minneapolis
TYS
Knoxville
$292 Roundtrip, found 23 hours ago
$292
Roundtrip
found 23 hours ago
Select Frontier Airlines flight, departing Thu, Aug 14 from Minneapolis to Knoxville, returning Sun, Aug 17, priced at $292 found 23 hours ago
American Airlines
Mon, May 26 - Thu, May 29
MSP
Minneapolis
TYS
Knoxville
$293 Roundtrip, found 1 day ago
$293
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, May 26 from Minneapolis to Knoxville, returning Thu, May 29, priced at $293 found 1 day ago
Delta
Thu, Aug 14 - Fri, Aug 22
MSP
Minneapolis
TYS
Knoxville
$299 Roundtrip, just found
$299
Roundtrip
just found
Select Delta flight, departing Thu, Aug 14 from Minneapolis to Knoxville, returning Fri, Aug 22, priced at $299 just found
United
Fri, Jul 25 - Sat, Jul 26
MSP
Minneapolis
TYS
Knoxville
$317 Roundtrip, found 3 days ago
$317
Roundtrip
found 3 days ago
Select United flight, departing Fri, Jul 25 from Minneapolis to Knoxville, returning Sat, Jul 26, priced at $317 found 3 days ago

Frequently asked questions

How much does a flight from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS) cost?
Pick up cheap return fares starting at $299 from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS). This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Delta flight leaving MSP on May 14 2025 and touching down at TYS. The price was last updated on April 23 2025 and has not changed since.
What is the cheapest month to fly from MSP to TYS?
The cheapest flights from MSP to TYS are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS)?
Take a nonstop flight with Delta Air Lines and fly straight from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS).
What is the cheapest airline that flies from MSP to TYS?
Book a flight from MSP to TYS with Delta. This carrier currently offers the cheapest one-way fare for this route, starting at $249. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from MSP on June 29 2025. Prices were last updated on April 23 2025 and have not changed since.
How many flights per day from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS)?
On average, there are 6 direct flights taking off from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS) each week. If you don’t find one that fits your schedule, consider taking a flight that includes a layover. Filter your search results on Expedia to include one or more stops and choose the next best option.
What are the most popular departure times for flights from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS)?
More travelers fly between MSP and TYS at 7 PM than at any other point in the day. Prefer a quieter experience? Consider flying outside peak hours and it’s possible you’ll save on your fare as well.
What day of the week has the most flights from MSP to TYS?
If you travel on a Friday, you’ll get the largest range of options for flights from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS).
What is the earliest flight from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS)?
The earliest flight departing from Minneapolis - St. Paul Intl. Airport (MSP) is at around 7:50PM UTC-6. Hop on this flight and you’ll reach McGhee Tyson Airport (TYS) at approximately 11:04PM UTC-5. The entire trip takes 2h 14m.
How long does it take to fly from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS)?
Flights from MSP to TYS have an average travel time of 2 hours and 14 minutes. The distance between these two airports is 790 mi.
What airline has the least delays from MSP to TYS?
Delta Air Lines has the best performance for on-time direct flights from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS), with an on-time score of 85%. Use the Expedia App to look up your flight schedule before you take off and receive notifications about any changes.
What is the best time to fly from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS)?
To avoid possible delays on the Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS) route, aim to travel before 3 PM. Departures after this time have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
What airports do you fly into for Knoxville from Minneapolis - St. Paul Intl. Airport (MSP)?
Explore your flight options from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS). This is the only airport in Knoxville you can arrive at if you’re taking a direct flight.
Is it cheaper to buy a plane ticket from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS) last-minute?
Booking your flight from MSP to TYS shortly before your journey is usually more expensive. However, if there’s some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a MSP to TYS flight and hotel package?
Compared with arranging flights and hotels separately, booking a MSP to TYS flight and hotel package with Expedia could lead to significant savings. What’s more, having everything in one place will take the stress out of planning your trip. Just pick your flights and choose from our extensive range of stays, then personalize your trip with extras like tours, car rentals and activities.
Can I cancel or change the date of my flight from Minneapolis - St. Paul Intl. Airport (MSP) to McGhee Tyson Airport (TYS)?
In most cases, you can reschedule or cancel your MSP to TYS flight. However, there may be additional fees, especially if your booking was made more than 24 hours ago. Double-check your itinerary for the airline’s guidelines and fees on flight changes, or if you need more information, visit our Customer Service portal.
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